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By NASA
4 Min Read Vision Changes on Space Station
NASA astronaut Jonny Kim, assisted by JAXA astronaut Takuya Onishi, performs an eye ultrasound on the International Space Station. Credits: NASA Science in Space July 2025
When astronauts began spending six months and more aboard the International Space Station, they started to notice changes in their vision. For example, many found that, as their mission progressed, they needed stronger reading glasses. Researchers studying this phenomenon identified swelling in the optic disc, which is where the optic nerve enters the retina, and flattening of the eye shape. These symptoms became known as Space-Associated Neuro-Ocular Syndrome (SANS).
NASA astronaut Suni Williams wears a cuff on her left leg as she conducts an eye exam for the Thigh Cuff investigation.NASA Microgravity causes a person’s blood and cerebrospinal fluid to shift toward the head and studies have suggested that these fluid shifts may be an underlying cause of SANS. A current investigation, Thigh Cuff, examines whether tight leg cuffs change the way fluid moves around inside the body, especially around the eyes and in the heart and blood vessels. If so, the cuffs could serve as a countermeasure against the problems associated with fluid shifts, including SANS. A simple and easy-to-use tool to counter the headward shift of body fluids could help protect astronauts on future missions to the Moon and Mars. The cuffs also could treat conditions on Earth that cause fluid to build up in the head or upper body, such as long-term bed rest and certain diseases.
Following fluid shifts
NASA astronaut Shane Kimbrough sets up optical coherence tomography hardware.NASA The Fluid Shifts investigation, conducted from 2015 through 2020, was the first to reveal changes in how blood drains from the brain in microgravity. Vision Impairment and Intracranial Pressure (VIIP) began testing the role those fluid shifts and resulting increased brain fluid pressure might play in the development of SANS. This research used a variety of measures including clinical eye exams with and without dilatation, imaging of the retina and associated blood vessels and nerves, noninvasive imaging to measure the thickness of retinal structures, and magnetic resonance imaging of the eye and optic nerve. In addition, approximately 300 astronauts completed questionnaires to document vision changes during their missions.
In one paper published from the research, scientists described how these imaging techniques have improved the understanding of SANS. The authors summarized emerging research on developing a head-mounted virtual reality display that can conduct multimodal, noninvasive assessment to help diagnose SANS.
Other researchers determined that measuring the optic nerve sheath diameter shows promise as a way to identify and quantify eye and vision changes during spaceflight. The paper also makes recommendations for standardizing imaging tools, measurement techniques, and other aspects of study design.
Another paper reported on an individual astronaut who had more severe than usual changes after a six-month spaceflight and certain factors that may have contributed. Researchers also observed improvement in the individual’s symptoms that may have been due to B vitamin supplementation and lower cabin carbon dioxide levels following departure of some crew members. While a single case does not allow researchers to determine cause and effect, the magnitude of the improvements suggest this individual may be more affected by environmental conditions such as carbon dioxide. This may have been the first attempt to mitigate SANS with inflight B vitamin supplementation.
Eyeball tissue stiffness
Optical coherence tomography image of the back of the eyeball (top) and thickness of the middle wall of the eye (bottom) from the SANSORI investigation.University of Montreal SANSORI, a CSA (Canadian Space Agency) investigation, used an imaging technique called Optical Coherence Tomography to examine whether reduced stiffness of eye tissue contributes to SANS. On Earth, changes in stiffness of the tissue around the eyeball have been associated with aging and conditions such as glaucoma and myopia. Researchers found that long-duration spaceflight affected the mechanical properties of eye tissues, which could contribute to the development of SANS. This finding could improve understanding of eye changes during spaceflight and in aging patients on Earth.
Genetic changes, artificial gravity
The MHU-8 investigation from JAXA (Japan Aerospace Exploration Agency), which examined changes in DNA and gene expression in mice after spaceflight, found changes in the optic nerve and retinal tissue. Researchers also found that artificial gravity may reduce these changes and could serve as a countermeasure on future missions.
These and other studies ultimately could help researchers prevent, diagnose, and treat vision impairment in crew members and people on Earth.
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By European Space Agency
Image: This image from Copernicus Sentinel-1 shows circular agricultural structures near Tabarjal, in the barren desert of northern Saudi Arabia. View the full article
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By NASA
NASA/Jonny Kim In this June 13, 2025, photo, NASA astronaut Anne McClain shows off a hamburger-shaped cake to celebrate 200 cumulative days in space for JAXA (Japan Aerospace Exploration Agency) astronaut Takuya Onishi since his first spaceflight as an Expedition 48-49 Flight Engineer in 2016.
Onishi and McClain launched to the International Space Station along with NASA astronaut Nichole Ayers and Roscosmos cosmonaut Kirill Peskov on March 14, 2025, as part of the Crew-10 mission. Aboard the orbital laboratory, the Crew-10 members conduct scientific research to prepare for human exploration beyond low Earth orbit and benefit humanity on Earth. McClain and Ayers also performed a spacewalk on May 1, 2025 – McClain’s third and Ayers’ first.
Check out the International Space Station blog to follow the crew’s research and other activities.
Image credit: NASA/Jonny Kim
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By European Space Agency
Video: 00:01:51 Space weather ‘reporter’ Vigil will be the world’s first space weather mission to be permanently positioned at Lagrange point 5, a unique vantage point that allows us to see solar activity days before it reaches Earth. ESA’s Vigil mission will be a dedicated operational space weather mission, sending data 24/7 from deep space.
Vigil’s tools as a space weather reporter at its unique location in deep space will drastically improve forecasting abilities. From there, Vigil can see ‘around the corner’ of the Sun and observe activity on the surface of the Sun days before it rotates into view from Earth. It can also watch the Sun-Earth line side-on, giving an earlier and clearer picture of coronal mass ejections (CMEs) heading toward Earth.
Radiation, plasma and particles flung towards Earth by the Sun can pose a very real risk to critical infrastructure our society relies on. This includes satellites for navigation, communications and banking services as well as power grids and radio communication on the ground.
A report by Lloyd’s of London estimates that a severe space weather event, caused by such an outburst of solar activity, could cost the global economy 2.4 trillion dollars over five years.
ESA’s response to this growing threat is Vigil, a cornerstone mission of the Agency’s Space Safety Programme, planned for launch in 2031. Vigil’s data will give us drastically improved early warnings and forecasts, which in turn help protect satellites, astronauts and critical infrastructure on the ground that we all depend on.
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By Space Force
The inaugural event welcomed over 100 international vendors representing 13 countries looking to partner with the Department of Defense and other governmental agencies within the space domain.
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