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By NASA
The International Space Station is pictured from the SpaceX Crew Dragon Endeavour during a fly around.NASA NASA astronaut Nick Hague and Roscosmos cosmonaut Aleksandr Gorbunov are headed to the International Space Station for the agency’s SpaceX Crew-9 mission in September. Once on station, these crew members will support scientific investigations that include studies of blood clotting, effects of moisture on plants grown in space, and vision changes in astronauts.
Here are details on some of the work scheduled during the Crew-9 expedition:
Blood cell development in space
Megakaryocytes Orbiting in Outer Space and Near Earth (MeF1) investigates how environmental conditions affect the development and function of megakaryocytes and platelets. Megakaryocytes, large cells found in bone marrow, and platelets, pieces of these cells, play important roles in blood clotting and immune response.
“Understanding the development and function of megakaryocytes and platelets during long-duration spaceflight is crucial to safeguarding the health of astronauts,” said Hansjorg Schwertz, principal investigator, at the University of Utah. “Sending megakaryocyte cell cultures into space offers a unique opportunity to explore their intricate differentiation process. Microgravity also may impact other blood cells, so the insights we gain are likely to enhance our overall comprehension of how spaceflight influences blood cell production.”
Results could provide critical knowledge about the risks of changes in inflammation, immune responses, and clot formation in spaceflight and on the ground.
Scanning electron-microscopy image of human platelets prior to launch to the International Space Station.University of Utah/Megakaryocytes PI Team Patches for NICER
The Neutron Star Interior Composition Explorer (NICER) telescope on the exterior of the space station measures X-rays emitted by neutron stars and other cosmic objects to help answer questions about matter and gravity.
In May 2023, NICER developed a “light leak” that allows sunlight to interfere with daytime measurements. Special patches designed to cover some of the damage will be installed during a future spacewalk, returning the instrument to around-the-clock operation.
“This will be the fourth science observatory and first X-ray telescope in orbit to be repaired by astronauts,” said principal investigator Keith Gendreau at NASA’s Goddard Space Flight Center in Greenbelt, Maryland. “In just a year, we diagnosed the problem, designed and tested a solution, and delivered it for launch. The space station team — from managers and safety experts to engineers and astronauts — helped us make it happen. We’re looking forward to getting back to normal science operations.”
This view shows NICER’s 56 X-ray concentrators. Astronauts plan to cover some of them with special patches on a future spacewalk. NASA Vitamins for vision
Some astronauts experience vision changes, a condition called Spaceflight-Associated Neuro-ocular Syndrome. The B Complex investigation tests whether a daily B vitamin supplement can prevent or mitigate this problem and assesses how genetics may influence individual response.
“We still do not know exactly what causes this syndrome, and not everyone gets it,” said Sara Zwart, principal investigator, at the University of Texas Medical Branch, Houston. “It is likely many factors, and biological variations that make some astronauts more susceptible than others.”
One such variation could be related to a metabolic pathway that requires B vitamins to function properly. Inefficiencies in this pathway can affect the inner lining of blood vessels, resulting in leaks that may contribute to vision changes. Providing B vitamins known to affect blood vessel function positively could minimize issues in genetically at-risk astronauts.
“The concept of this study is based on 13 years of flight and ground research,” Zwart said. “We are excited to finally flight test a low-risk countermeasure that could mitigate the risk on future missions, including those to Mars.”
NASA astronaut Mark Vande Hei conducts a vision exam on the International Space StationNASA Watering the space garden
As people travel farther from Earth for longer, growing food becomes increasingly important. Scientists conducted many plant growth experiments on the space station using its Veggie hardware, including Veg-01B, which demonstrated that ‘Outredgeous’ red romaine lettuce is suitable for crop production in space.
Plant Habitat-07 uses this lettuce to examine how moisture conditions affect the nutritional quality and microbial safety of plants. The Advanced Plant Habitat controls humidity, temperature, air, light, and soil moisture, creating the precise conditions needed for the experiment.
Using a plant known to grow well in space removes a challenging variable from the equation, explained Chad Vanden Bosch, principal investigator at Redwire, and this lettuce also has been proven to be safe to consume when grown in space.
“For crews building a base on the Moon or Mars, tending to plants may be low on their list of responsibilities, so plant growth systems need to be automated,” Bosch said. “Such systems may not always provide the perfect growing conditions, though, so we need to know if plants grown in suboptimal conditions are safe to consume.”
This preflight image shows lettuce grown under control (left) and flood (right) moisture treatments. Plant Habitat-07 team Melissa Gaskill
International Space Station Research Communications Team
NASA’s Johnson Space Center
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By NASA
The four-person crew of the Polaris Dawn mission pictured wearing their SpaceX extravehicular activity suits.Credit: SpaceX NASA researchers will soon benefit from a suite of experiments flying aboard a new fully-commercial human spaceflight mission, strengthening future agency science as we venture to the Moon, Mars and beyond.
The experiments are flying as part of the Polaris Dawn mission which launched aboard a SpaceX Dragon spacecraft and Falcon 9 rocket earlier today.
The four-person Polaris Dawn crew of Jared Isaacman, Scott “Kidd” Poteet, Sarah Gillis, and Anna Menon will conduct science during the mission including essential health and human performance research for NASA’s Human Research Program. The research will help NASA scientists better understand how exposure to space conditions affects the human body. The crew will test new medical approaches and technology on telemedicine capabilities, gather data on space motion sickness, and better characterize flight-associated injury risks.
“Each mission, whether the crew is comprised of commercial or NASA astronauts, provides a key opportunity to expand our knowledge about how spaceflight affects human health,” said Jancy McPhee, associate chief scientist for human research at NASA. “Information gathered from Polaris Dawn will give us critical insights to help NASA plan for deeper space travel to the Moon and Mars.”
The crew will test drive, a commercial device that can collect and integrate measurements of health, including blood pressure, heart rate, respiration rate, and temperature. The technology also provides ultrasound imaging and larynx and throat-focused video camera capabilities, and includes an experimental telemedicine feature that could help diagnose crew members in near-real time.
To test this technology during the mission, crew members will compare vital sign collection from the device with data gathered from standard periodic health status exams. The technology’s telemedicine feature, which relies on SpaceX’s Starlink communications system to connect with doctors and specialists on Earth, will also be tested during a simulation. During the test, the device will attempt to offer an appropriate diagnosis based on crew inputs and available documentation.
“Crew members will need to be more self-reliant during lengthy missions, and we hope that telemedicine can provide crews with assistance,” said McPhee.
Another research project aims to better understand and prevent the motion sickness symptoms that many astronauts experience in space. Participating crew members will describe their motion sickness symptoms, what interventions they tried to alleviate their symptoms, and whether any approaches helped.
A separate NASA-based research project will survey crew members after their mission to see whether they experienced any injuries or discomfort during re-entry to Earth.
“Our team will take the crew’s survey data and combine it with information gathered from sensors on the spacecraft. This will allow us to link crews’ reported experiences and health outcomes with the spacecraft’s dynamics and landing loads,” said Preston Greenhalgh, an injury biomechanist at NASA who is leading this work.
Crew members also will participate in a variety of other health studies on behalf of the NASA-funded TRISH (Translational Research Institute for Health), a consortium with various academic institutions. As part of that work, the Polaris Dawn mission will set a new baseline for collecting standard health data on commercial spaceflights, creating a complement to the datasets routinely collected from NASA astronauts and missions.
Polaris Dawn crew members participating in these TRISH studies will provide data about how spaceflight affects mental and physical health through a rigorous set of medical tests and scans completed before, after, and during the mission. The work will include assessments of behavior, sleep, bone density, eye health, cognitive function, and other factors, as well as analysis of blood, urine, and respiration.
“We’re so grateful to the crew members who volunteer to be part of NASA’s work. The insights that we gain from each study may trigger breakthroughs that will help ensure future mission success,” said McPhee.
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NASA’s Human Research Program pursues the best methods and technologies to support safe, productive human space travel. Through science conducted in laboratories, ground-based analogs, commercial missions, and the International Space Station, the program scrutinizes how spaceflight affects human bodies and behaviors. Such research continues to drive NASA’s mission to innovate ways that keep astronauts healthy and mission-ready as space exploration expands to the Moon, Mars, and beyond.
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