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By NASA
A host of scientific investigations await the crew of NASA’s SpaceX Crew-11 mission during their long-duration expedition aboard the International Space Station. NASA astronauts Zena Cardman and Mike Fincke, and JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui, are set to study plant cell division and microgravity’s effects on bacteria-killing viruses, as well as perform experiments to produce a higher volume of human stem cells and generate on-demand nutrients.
Here are details on some of the research scheduled during the Crew-11 mission:
Making more stem cells
Cultures of stem cells grown in 2D on Earth, left, and as 3D spheres in simulated microgravity on Earth.BioServe A stem cell investigation called StemCellEx-IP1 evaluates using microgravity to produce large numbers of induced pluripotent stem cells. Made by reprogramming skin or blood cells, these stem cells can transform into any type of cell in the body and are used in regenerative medicine therapies for many diseases. However, producing enough cells on the ground is a challenge.
Researchers plan to use the microgravity environment aboard the space station to demonstrate whether generating 1,000 times more cells is possible and whether these cells are of higher quality and better for clinical use than those made on Earth. If proven, this could significantly improve future patient outcomes.
“This type of stem cell research is a chance to find treatments and maybe even cures for diseases that currently have none,” said Tobias Niederwieser of BioServe Space Technologies, which developed the investigation. “This represents an incredible potential to make life here on Earth better for all of us. We can take skin or blood cells from a patient, convert them into stem cells, and produce custom cell-therapy with little risk for rejection, as they are the person’s own cells.”
Alternative to antibiotics
Genes in Space-12 student investigators Isabella Chuang, left, and Julia Gross, middle, with mentor Kayleigh Ingersoll Omdahl.Genes in Space Genes in Space is a series of competitions in which students in grades 7 through 12 design DNA experiments that are flown to the space station. Genes in Space-12 examines the effects of microgravity on interactions between certain bacteria and bacteriophages, which are viruses that infect and kill bacteria. Bacteriophages already are used to treat bacterial infections on Earth.
“Boeing and miniPCR bio co-founded this competition to bring real-world scientific experiences to the classroom and promote molecular biology investigations on the space station,” said Scott Copeland of Boeing, and co-founder of Genes in Space. “This
investigation could establish a foundation for using these viruses to treat bacterial infections in space, potentially decreasing the dependence on antibiotics.”
“Previous studies indicate that bacteria may display increased growth rates and virulence in space, while the antibiotics used to combat them may be less effective,” said Dr. Ally Huang, staff scientist at miniPCR bio. “Phages produced in space could have profound implications for human health, microbial control, and the sustainability of long-duration remote missions. Phage therapy tools also could revolutionize how we manage bacterial infections and microbial ecosystems on Earth.”
Edible organisms
A purple, pre-incubation BioNutrients-3 bag, left, and a pink bag, right, which has completed incubation, on a purple and pink board used for comparison.NASA Some vitamins and nutrients in foods and supplements lose their potency during prolonged storage, and insufficient intake of even a single nutrient can lead to serious diseases, such as a vitamin C deficiency, causing scurvy. The BioNutrients-3 experiment builds on previous investigations looking at ways to produce on-demand nutrients in space using genetically engineered organisms that remain viable for years. These include yogurt and a yeast-based beverage made from yeast strains previously tested aboard station, as well as a new, engineered co-culture that produces multiple nutrients in one sample bag.
“BioNutrients-3 includes multiple food safety features, including pasteurization to kill microorganisms in the sample and a demonstration of the feasibility of using a sensor called E-Nose that simulates an ultra-sensitive nose to detect pathogens,” said Kevin Sims, project manager at NASA’s Ames Research Center in California’s Silicon Valley.
Another food safety feature is a food-grade pH indicator to track bacterial growth.
“These pH indicators help the crew visualize the progress of the yogurt and kefir samples,” Sims said. “As the organisms grow, they generate lactic acid, which lowers the pH and turns the indicator pink.”
The research also features an investigation of yogurt passage, which seeds new cultures using a bit of yogurt from a finished bag, much like maintaining a sourdough bread starter. This method could sustain a culture over multiple generations, eliminating concerns about yogurt’s shelf life during a mission to the Moon or Mars while reducing launch mass.
Understanding cell division
Cells of green algae dividing.University of Toyama The JAXA Plant Cell Division investigation examines how microgravity affects cell division in green algae and a strain of cultured tobacco cells. Cell division is a fundamental element of plant growth, but few studies have examined it in microgravity.
“The tobacco cells divide frequently, making the process easy to observe,” said Junya Kirima of JAXA. “We are excited to reveal the effects of the space environment on plant cell division and look forward to performing time-lapse live imaging of it aboard the space station.”
Understanding this process could support the development of better methods for growing plants for food in space, including on the Moon and Mars. This investigation also could provide insight to help make plant production systems on Earth more efficient.
For nearly 25 years, people have lived and worked continuously aboard the International Space Station, advancing scientific knowledge and conducting critical research for the benefit of humanity and our home planet. Space station research supports the future of human spaceflight as NASA looks toward deep space missions to the Moon under the Artemis campaign and in preparation for future human missions to Mars, as well as expanding commercial opportunities in low Earth orbit and beyond.
Learn more about the International Space Station at:
https://www.nasa.gov/station
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By NASA
The Axiom Mission 4 crew launched on June 25, 2025, aboard a SpaceX Dragon spacecraft to the International Space Station from NASA’s Kennedy Space Center in Florida. From left to right: Tibor Kapu of Hungary, ISRO (Indian Space Research Organization) astronaut Shubhanshu Shukla, former NASA astronaut Peggy Whitson, and ESA (European Space Agency) astronaut Sławosz Uznański-Wiśniewski of Poland (Credit: Axiom Space). The NASA-supported fourth private astronaut mission to the International Space Station, Axiom Mission 4, completed its flight as part of the agency’s efforts to demonstrate demand and build operational knowledge for future commercial space stations.
The four-person crew safely returned to Earth, splashing down off the coast of California at 5:31 a.m. EDT on Tuesday, aboard a SpaceX Dragon spacecraft. Teams aboard SpaceX recovery vessels retrieved the spacecraft and astronauts.
Peggy Whitson, former NASA astronaut and director of human spaceflight at Axiom Space, ISRO (Indian Space Research Organization) astronaut Shubhanshu Shukla, and ESA (European Space Agency) project astronaut Sławosz Uznański-Wiśniewski of Poland, and Hungarian to Orbit (HUNOR) astronaut Tibor Kapu of Hungary, completed about two and a half weeks in space.
The Axiom Mission 4 crew launched at 2:31 a.m. on June 25, on a Falcon 9 rocket from NASA’s Kennedy Space Center in Florida. Approximately 28 hours later, Dragon docked to the space-facing port of the space station’s Harmony module. The astronauts undocked at 7:15 a.m. on July 14, to begin the trip home.
The crew conducted microgravity research, educational outreach, and commercial activities. The spacecraft will return to Florida for inspection and processing at SpaceX’s refurbishing facilities. Throughout their mission, the astronauts conducted about 60 science experiments, and returned science, including NASA cargo, back to Earth.
A collaboration between NASA and ISRO allowed Axiom Mission 4 to deliver on a commitment highlighted by President Trump and Indian Prime Minister Narendra Modi to send the first ISRO astronaut to the station. The space agencies participated in five joint science investigations and two in-orbit science, technology, engineering, and mathematics demonstrations. NASA and ISRO have a long-standing relationship built on a shared vision to advance scientific knowledge and expand space collaboration.
The private mission also carried the first astronauts from Poland and Hungary to stay aboard the space station.
The International Space Station is a springboard for developing a low Earth orbit economy. NASA’s goal is to achieve a strong economy off the Earth where the agency can purchase services as one of many customers to meet its science and research objectives in microgravity. NASA’s commercial strategy for low Earth orbit provides the government with reliable and safe services at a lower cost, enabling the agency to focus on Artemis missions to the Moon in preparation for Mars while also continuing to use low Earth orbit as a training and proving ground for those deep space missions.
Learn more about NASA’s commercial space strategy at:
https://www.nasa.gov/commercial-space
News Media Contacts:
Claire O’Shea
Headquarters, Washington
202-358-1100
claire.a.o’shea@nasa.gov
Anna Schneider
Johnson Space Center, Houston
281-483-5111
anna.c.schneider@nasa.gov
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By NASA
NASA/Johns Hopkins University Applied Physics Laboratory/Southwest Research Institute/Alex Parker This image, taken by NASA’s New Horizons spacecraft on July 14, 2015, is the most accurate natural color image of Pluto. This natural-color image results from refined calibration of data gathered by New Horizons’ color Multispectral Visible Imaging Camera (MVIC). The processing creates images that would approximate the colors that the human eye would perceive, bringing them closer to “true color” than the images released near the encounter. This single color MVIC scan includes no data from other New Horizons imagers or instruments added. The striking features on Pluto are clearly visible, including the bright expanse of Pluto’s icy, nitrogen-and-methane rich “heart,” Sputnik Planitia.
Image credit: NASA/Johns Hopkins University Applied Physics Laboratory/Southwest Research Institute/Alex Parker
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By NASA
The crew of NASA’s SpaceX Crew-11 mission sit inside a Dragon training spacecraft at SpaceX in Hawthorne, California. Pictured from left: Roscosmos cosmonaut Oleg Platonov, NASA astronauts Mike Fincke and Zena Cardman, and JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui (Credit: SpaceX). NASA’s SpaceX Crew-11 mission is set to launch a four-person crew to the International Space Station later this summer. Some of the crew have volunteered to participate in a series of experiments to address health challenges astronauts may face on deep space missions during NASA’s Artemis campaign and future human expeditions to Mars.
The research during Crew-11 includes simulated lunar landings, tactics to safeguard vision, and other human physiology studies led by NASA’s Human Research Program.
Select crew members will participate in a series of simulated Moon landings, before, during, and after their flight. Using a handheld controller and multiple screens, the astronauts will fly through simulated scenarios created to resemble the lunar South Pole region that Artemis crews plan to visit. This experiment allows researchers to evaluate how different gravitational forces may disorient astronauts and affect their ability to pilot a spacecraft, like a lunar lander.
“Even though many landing tasks are automated, astronauts must still know how to monitor the controls and know when to take over to ensure a safe landing,” said Scott Wood, a neuroscientist at NASA’s Johnson Space Center in Houston coordinating the scientific investigation. “Our study assesses exactly how changes in gravity affect spatial awareness and piloting skills that are important for navigating these scenarios.”
A ground control group completing the same tasks over a similar timeframe will help scientists better understand gravitational effects on human performance. The experiment’s results could inform the pilot training needed for future Artemis crews.
“Experiencing weightlessness for months and then feeling greater levels of gravity on a planet like Mars, for example, may increase the risk of disorientation,” said Wood. “Our goal is to help astronauts adapt to any gravitational change, whether it’s to the Moon, a new planet, or landing back on Earth.”
Other studies during the mission will explore possible ways to treat or prevent a group of eye and brain changes that can occur during long-duration space travel, called spaceflight associated neuro-ocular syndrome (SANS).
Some researchers suspect the redistribution of bodily fluids in constant weightlessness may increase pressure in the head and contribute to SANS. One study will investigate fluid pressure on the brain while another will examine how the body processes B vitamins and whether supplements can affect how astronauts respond to bodily fluid shifts. Participating crew members will test whether a daily B vitamin supplement can eliminate or ease symptoms of SANS. Specific crew members also will wear thigh cuffs to keep bodily fluids from traveling headward.
Crew members also will complete another set of experiments, called CIPHER (Complement of Integrated Protocols for Human Exploration Research), which measures how multiple systems within the human body change in space. The study includes vision assessments, MRI scans, and other medical exams to provide a complete overview of the whole body’s response to long-duration spaceflight.
Several other studies involving human health and performance are also a part of Crew-11’s science portfolio. Crew members will contribute to a core set of measurements called Spaceflight Standard Measures, which collects physical data and biological samples from astronauts and stores them for other comparative studies. Participants will supply biological samples, such as blood and urine, for a study characterizing how spaceflight alters astronauts’ genetic makeup. In addition, volunteers will test different exercise regimens to help scientists explore what activities remain essential for long-duration journeys.
After landing, participating crew members will complete surveys to track any discomfort, such as scrapes or bruises, acquired from re-entry. The data will help clarify whether mission length increases injury risks and could help NASA design landing systems on future spacecraft as NASA prepares to travel to the Moon, Mars, and beyond.
NASA’s Human Research Program pursues methods and technologies to support safe, productive human space travel. Through science conducted in laboratories, ground-based analogs, and aboard the International Space Station, the program investigates how spaceflight affects human bodies and behaviors. Such research drives NASA’s quest to innovate ways that keep astronauts healthy and mission-ready.
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By NASA
The four crew members of NASA’s SpaceX Crew-11 mission to the International Space Station train inside a SpaceX Dragon spacecraft in Hawthorne, California. From left to right: Roscosmos cosmonaut Oleg Platonov, NASA astronauts Mike Fincke and Zena Cardman, and JAXA astronaut Kimiya Yui.Credit: SpaceX NASA and its partners will discuss the upcoming crew rotation to the International Space Station during a pair of news conferences on Thursday, July 10, from the agency’s Johnson Space Center in Houston.
First is an overview news conference at 12 p.m. EDT with mission leadership discussing final launch and mission preparations on the agency’s YouTube channel.
Next, crew will participate in a news conference at 2 p.m. on NASA’s YouTube channel, followed by individual astronaut interviews at 3 p.m. This is the final media opportunity with Crew-11 before they travel to NASA’s Kennedy Space Center in Florida for launch.
The Crew-11 mission, targeted to launch in late July/early August, will carry NASA astronauts Zena Cardman and Mike Fincke, JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui, and Roscosmos cosmonaut Oleg Platonov to the orbiting laboratory. The crew will launch aboard a SpaceX Dragon spacecraft on the company’s Falcon 9 rocket from Launch Complex 39A.
United States-based media seeking to attend in person must contact the NASA Johnson newsroom no later than 5 p.m. on Monday, July 7, at 281-483-5111 or jsccommu@mail.nasa.gov. A copy of NASA’s media accreditation policy is available online.
Any media interested in participating in the news conferences by phone must contact the Johnson newsroom by 9:45 a.m. the day of the event. Media seeking virtual interviews with the crew must submit requests to the Johnson newsroom by 5 p.m. on Monday, July 7.
Briefing participants are as follows (all times Eastern and subject to change based on real-time operations):
12 p.m.: Mission Overview News Conference
Steve Stich, manager, Commercial Crew Program, NASA Kennedy Bill Spetch, operations integration manager, International Space Station Program, NASA Johnson NASA’s Space Operations Mission Directorate representative Sarah Walker, director, Dragon Mission Management, SpaceX Mayumi Matsuura, vice president and director general, Human Spaceflight Technology Directorate, JAXA 2 p.m.: Crew News Conference
Zena Cardman, Crew-11 commander, NASA Mike Fincke, Crew-11 pilot, NASA Kimiya Yui, Crew-11 mission specialist, JAXA Oleg Platonov, Crew-11 mission specialist, Roscosmos 3 p.m.: Crew Individual Interview Opportunities
Crew-11 members available for a limited number of interviews
Selected as a NASA astronaut in 2017, Cardman will conduct her first spaceflight. The Williamsburg, Virginia, native holds a bachelor’s degree in Biology and a master’s in Marine Sciences from the University of North Carolina at Chapel Hill. At the time of selection, she was pursuing a doctorate in geosciences. Cardman’s geobiology and geochemical cycling research focused on subsurface environments, from caves to deep sea sediments. Since completing initial training, Cardman has supported real-time station operations and lunar surface exploration planning. Follow @zenanaut on X and @zenanaut on Instagram.
This will be Fincke’s fourth trip to the space station, having logged 382 days in space and nine spacewalks during Expedition 9 in 2004, Expedition 18 in 2008, and STS-134 in 2011, the final flight of space shuttle Endeavour. Throughout the past decade, Fincke has applied his expertise to NASA’s Commercial Crew Program, advancing the development and testing of the SpaceX Dragon spacecraft and Boeing Starliner spacecraft toward operational certification. The Emsworth, Pennsylvania, native is a graduate of the United States Air Force Test Pilot School and holds bachelors’ degrees from the Massachusetts Institute of Technology, Cambridge, in both aeronautics and astronautics, as well as Earth, atmospheric and planetary sciences. He also has a master’s degree in aeronautics and astronautics from Stanford University in California. Fincke is a retired U.S. Air Force colonel with more than 2,000 flight hours in over 30 different aircraft. Follow @AstroIronMike on X and Instagram.
With 142 days in space, this will be Yui’s second trip to the space station. After his selection as a JAXA astronaut in 2009, Yui flew as a flight engineer for Expedition 44/45 and became the first Japanese astronaut to capture JAXA’s H-II Transfer Vehicle using the station’s robotic arm. In addition to constructing a new experimental environment aboard Kibo, he conducted a total of 21 experiments for JAXA. In November 2016, Yui was assigned as chief of the JAXA Astronaut Group. He graduated from the School of Science and Engineering at the National Defense Academy of Japan in 1992. He later joined the Air Self-Defense Force at the Japan Defense Agency (currently the Ministry of Defense). In 2008, Yui joined the Air Staff Office at the Ministry of Defense as a lieutenant colonel. Follow @astro_kimiya on X.
The Crew-11 mission also will be Platonov’s first spaceflight. Before his selection as a cosmonaut in 2018, Platonov earned a degree in engineering from Krasnodar Air Force Academy in aircraft operations and air traffic management. He also earned a bachelor’s degree in state and municipal management in 2016 from the Far Eastern Federal University in Vladivostok, Russia. Assigned as a test cosmonaut in 2021, he has experience in piloting aircraft, zero gravity training, scuba diving, and wilderness survival.
For more information about the mission, visit:
https://www.nasa.gov/commercialcrew
-end-
Claire O’Shea / Joshua Finch
Headquarters, Washington
202-358-1100
claire.a.o’shea@nasa.gov / joshua.a.finch@nasa.gov
Sandra Jones / Joseph Zakrzewski
Johnson Space Center, Houston
281-483-5111
sandra.p.jones@nasa.gov / Joseph.a.zakrzewski@nasa.gov
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Last Updated Jul 02, 2025 LocationNASA Headquarters Related Terms
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