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Europa Clipper: NASA’s Mission to Jupiter's Ocean Moon (Mission Trailer)
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By NASA
A host of scientific investigations await the crew of NASA’s SpaceX Crew-11 mission during their long-duration expedition aboard the International Space Station. NASA astronauts Zena Cardman and Mike Fincke, and JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui, are set to study plant cell division and microgravity’s effects on bacteria-killing viruses, as well as perform experiments to produce a higher volume of human stem cells and generate on-demand nutrients.
Here are details on some of the research scheduled during the Crew-11 mission:
Making more stem cells
Cultures of stem cells grown in 2D on Earth, left, and as 3D spheres in simulated microgravity on Earth.BioServe A stem cell investigation called StemCellEx-IP1 evaluates using microgravity to produce large numbers of induced pluripotent stem cells. Made by reprogramming skin or blood cells, these stem cells can transform into any type of cell in the body and are used in regenerative medicine therapies for many diseases. However, producing enough cells on the ground is a challenge.
Researchers plan to use the microgravity environment aboard the space station to demonstrate whether generating 1,000 times more cells is possible and whether these cells are of higher quality and better for clinical use than those made on Earth. If proven, this could significantly improve future patient outcomes.
“This type of stem cell research is a chance to find treatments and maybe even cures for diseases that currently have none,” said Tobias Niederwieser of BioServe Space Technologies, which developed the investigation. “This represents an incredible potential to make life here on Earth better for all of us. We can take skin or blood cells from a patient, convert them into stem cells, and produce custom cell-therapy with little risk for rejection, as they are the person’s own cells.”
Alternative to antibiotics
Genes in Space-12 student investigators Isabella Chuang, left, and Julia Gross, middle, with mentor Kayleigh Ingersoll Omdahl.Genes in Space Genes in Space is a series of competitions in which students in grades 7 through 12 design DNA experiments that are flown to the space station. Genes in Space-12 examines the effects of microgravity on interactions between certain bacteria and bacteriophages, which are viruses that infect and kill bacteria. Bacteriophages already are used to treat bacterial infections on Earth.
“Boeing and miniPCR bio co-founded this competition to bring real-world scientific experiences to the classroom and promote molecular biology investigations on the space station,” said Scott Copeland of Boeing, and co-founder of Genes in Space. “This
investigation could establish a foundation for using these viruses to treat bacterial infections in space, potentially decreasing the dependence on antibiotics.”
“Previous studies indicate that bacteria may display increased growth rates and virulence in space, while the antibiotics used to combat them may be less effective,” said Dr. Ally Huang, staff scientist at miniPCR bio. “Phages produced in space could have profound implications for human health, microbial control, and the sustainability of long-duration remote missions. Phage therapy tools also could revolutionize how we manage bacterial infections and microbial ecosystems on Earth.”
Edible organisms
A purple, pre-incubation BioNutrients-3 bag, left, and a pink bag, right, which has completed incubation, on a purple and pink board used for comparison.NASA Some vitamins and nutrients in foods and supplements lose their potency during prolonged storage, and insufficient intake of even a single nutrient can lead to serious diseases, such as a vitamin C deficiency, causing scurvy. The BioNutrients-3 experiment builds on previous investigations looking at ways to produce on-demand nutrients in space using genetically engineered organisms that remain viable for years. These include yogurt and a yeast-based beverage made from yeast strains previously tested aboard station, as well as a new, engineered co-culture that produces multiple nutrients in one sample bag.
“BioNutrients-3 includes multiple food safety features, including pasteurization to kill microorganisms in the sample and a demonstration of the feasibility of using a sensor called E-Nose that simulates an ultra-sensitive nose to detect pathogens,” said Kevin Sims, project manager at NASA’s Ames Research Center in California’s Silicon Valley.
Another food safety feature is a food-grade pH indicator to track bacterial growth.
“These pH indicators help the crew visualize the progress of the yogurt and kefir samples,” Sims said. “As the organisms grow, they generate lactic acid, which lowers the pH and turns the indicator pink.”
The research also features an investigation of yogurt passage, which seeds new cultures using a bit of yogurt from a finished bag, much like maintaining a sourdough bread starter. This method could sustain a culture over multiple generations, eliminating concerns about yogurt’s shelf life during a mission to the Moon or Mars while reducing launch mass.
Understanding cell division
Cells of green algae dividing.University of Toyama The JAXA Plant Cell Division investigation examines how microgravity affects cell division in green algae and a strain of cultured tobacco cells. Cell division is a fundamental element of plant growth, but few studies have examined it in microgravity.
“The tobacco cells divide frequently, making the process easy to observe,” said Junya Kirima of JAXA. “We are excited to reveal the effects of the space environment on plant cell division and look forward to performing time-lapse live imaging of it aboard the space station.”
Understanding this process could support the development of better methods for growing plants for food in space, including on the Moon and Mars. This investigation also could provide insight to help make plant production systems on Earth more efficient.
For nearly 25 years, people have lived and worked continuously aboard the International Space Station, advancing scientific knowledge and conducting critical research for the benefit of humanity and our home planet. Space station research supports the future of human spaceflight as NASA looks toward deep space missions to the Moon under the Artemis campaign and in preparation for future human missions to Mars, as well as expanding commercial opportunities in low Earth orbit and beyond.
Learn more about the International Space Station at:
https://www.nasa.gov/station
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By European Space Agency
After 20 days in space, ESA project astronaut Sławosz Uznański-Wiśniewski and his Axiom Mission 4 (Ax-4) crewmates returned safely to Earth today, 15 July 2025.
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By NASA
6 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
NASA Ames research scientist Kristina Pistone monitors instrument data while onboard the Twin Otter aircraft, flying over Monterey Bay during the October 2024 deployment of the AirSHARP campaign. NASA/Samuel Leblanc In autumn 2024, California’s Monterey Bay experienced an outsized phytoplankton bloom that attracted fish, dolphins, whales, seabirds, and – for a few weeks in October – scientists. A team from NASA’s Ames Research Center in Silicon Valley, with partners at the University of California, Santa Cruz (UCSC), and the Naval Postgraduate School, spent two weeks on the California coast gathering data on the atmosphere and the ocean to verify what satellites see from above. In spring 2025, the team returned to gather data under different environmental conditions.
Scientists call this process validation.
Setting up the Campaign
The PACE mission, which stands for Plankton, Aerosol, Cloud, ocean Ecosystem, was launched in February 2024 and designed to transform our understanding of ocean and atmospheric environments. Specifically, the satellite will give scientists a finely detailed look at life near the ocean surface and the composition and abundance of aerosol particles in the atmosphere.
Whenever NASA launches a new satellite, it sends validation science teams around the world to confirm that the data from instruments in space match what traditional instruments can see at the surface. AirSHARP (Airborne aSsessment of Hyperspectral Aerosol optical depth and water-leaving Reflectance Product Performance for PACE) is one of these teams, specifically deployed to validate products from the satellite’s Ocean Color Instrument (OCI).
The OCI spectrometer works by measuring reflected sunlight. As sunlight bounces off of the ocean’s surface, it creates specific shades of color that researchers use to determine what is in the water column below. To validate the OCI data, research teams need to confirm that measurements directly at the surface match those from the satellite. They also need to understand how the atmosphere is changing the color of the ocean as the reflected light is traveling back to the satellite.
In October 2024 and May 2025, the AirSHARP team ran simultaneous airborne and seaborne campaigns. Going into the field during different seasons allows the team to collect data under different environmental conditions, validating as much of the instrument’s range as possible.
Over 13 days of flights on a Twin Otter aircraft, the NASA-led team used instruments called 4STAR-B (Spectrometer for sky-scanning sun Tracking Atmospheric Research B), and the C-AIR (Coastal Airborne In-situ Radiometer) to gather data from the air. At the same time, partners from UCSC used a host of matching instruments onboard the research vessel R/V Shana Rae to gather data from the water’s surface.
Ocean Color and Water Leaving Reflectance
The Ocean Color Instrument measures something called water leaving reflectance, which provides information on the microscopic composition of the water column, including water molecules, phytoplankton, and particulates like sand, inorganic materials, and even bubbles. Ocean color varies based on how these materials absorb and scatter sunlight. This is especially useful for determining the abundance and types of phytoplankton.
Photographs taken out the window of the Twin Otter aircraft during the October 2024 AirSHARP deployment showcase the variation in ocean color, which indicates different molecular composition of the water column beneath. The red color in several of these photos is due to a phytoplankton bloom – in this case a growth of red algae. NASA/Samuel Leblanc
The AirSHARP team used radiometers with matching technology – C-AIR from the air and C-OPS (Compact Optical Profiling System) from the water – to gather water leaving reflectance data.
“The C-AIR instrument is modified from an instrument that goes on research vessels and takes measurements of the water’s surface from very close range,” said NASA Ames research scientist Samuel LeBlanc. “The issue there is that you’re very local to one area at a time. What our team has done successfully is put it on an aircraft, which enables us to span the entire Monterey Bay.”
The larger PACE validation team will compare OCI measurements with observations made by the sensors much closer to the ocean to ensure that they match, and make adjustments when they don’t.
Aerosol Interference
One factor that can impact OCI data is the presence of manmade and natural aerosols, which interact with sunlight as it moves through the atmosphere. An aerosol refers to any solid or liquid suspended in the air, such as smoke from fires, salt from sea spray, particulates from fossil fuel emissions, desert dust, and pollen.
Imagine a 420 mile-long tube, with the PACE satellite at one end and the ocean at the other. Everything inside the tube is what scientists refer to as the atmospheric column, and it is full of tiny particulates that interact with sunlight. Scientists quantify this aerosol interaction with a measurement called aerosol optical depth.
“During AirSHARP, we were essentially measuring, at different wavelengths, how light is changed by the particles present in the atmosphere,” said NASA Ames research scientist Kristina Pistone. “The aerosol optical depth is a measure of light extinction, or how much light is either scattered away or absorbed by aerosol particulates.”
The team measured aerosol optical depth using the 4STAR-B spectrometer, which was engineered at NASA Ames and enables scientists to identify which aerosols are present and how they interact with sunlight.
Twin Otter Aircraft
AirSHARP principal investigator Liane Guild walks towards a Twin Otter aircraft owned and operated by the Naval Postgraduate School. The aircraft’s ability to perform complex, low-altitude flights made it the ideal platform to fly multiple instruments over Monterey Bay during the AirSHARP campaign. NASA/Samuel Leblanc
Flying these instruments required use of a Twin Otter plane, operated by the Naval Postgraduate School (NPS). The Twin Otter is unique for its ability to perform extremely low-altitude flights, making passes down to 100 feet above the water in clear conditions.
“It’s an intense way to fly. At that low height, the pilots continually watch for and avoid birds, tall ships, and even wildlife like breaching whales,” said Anthony Bucholtz, director of the Airborne Research Facility at NPS.
With the phytoplankton bloom attracting so much wildlife in a bay already full of ships, this is no small feat. “The pilots keep a close eye on the radar, and fly by hand,” Bucholtz said, “all while following careful flight plans crisscrossing Monterey Bay and performing tight spirals over the Research Vessel Shana Rae.”
Campaign Data
Data gathered from the 2024 phase of this campaign is available on two data archive systems. Data from the 4STAR instrument is available in the PACE data archive and data from C-AIR is housed in the SeaBASS data archive.
Other data from the NASA PACE Validation Science Team is available through the PACE website: https://pace.oceansciences.org/pvstdoi.htm#
Samuel LeBlanc and Kristina Pistone are funded via the Bay Area Environmental Research Institute (BAERI), which is a scientist-founded nonprofit focused on supporting Earth and space sciences.
About the Author
Milan Loiacono
Science Communication SpecialistMilan Loiacono is a science communication specialist for the Earth Science Division at NASA Ames Research Center.
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Last Updated Jun 26, 2025 Related Terms
Ames Research Center's Science Directorate Ames Research Center Earth Earth Science Earth Science Division PACE (Plankton, Aerosol, Cloud, Ocean Ecosystem) Science Mission Directorate Explore More
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