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By NASA
A host of scientific investigations await the crew of NASA’s SpaceX Crew-11 mission during their long-duration expedition aboard the International Space Station. NASA astronauts Zena Cardman and Mike Fincke, and JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui, are set to study plant cell division and microgravity’s effects on bacteria-killing viruses, as well as perform experiments to produce a higher volume of human stem cells and generate on-demand nutrients.
Here are details on some of the research scheduled during the Crew-11 mission:
Making more stem cells
Cultures of stem cells grown in 2D on Earth, left, and as 3D spheres in simulated microgravity on Earth.BioServe A stem cell investigation called StemCellEx-IP1 evaluates using microgravity to produce large numbers of induced pluripotent stem cells. Made by reprogramming skin or blood cells, these stem cells can transform into any type of cell in the body and are used in regenerative medicine therapies for many diseases. However, producing enough cells on the ground is a challenge.
Researchers plan to use the microgravity environment aboard the space station to demonstrate whether generating 1,000 times more cells is possible and whether these cells are of higher quality and better for clinical use than those made on Earth. If proven, this could significantly improve future patient outcomes.
“This type of stem cell research is a chance to find treatments and maybe even cures for diseases that currently have none,” said Tobias Niederwieser of BioServe Space Technologies, which developed the investigation. “This represents an incredible potential to make life here on Earth better for all of us. We can take skin or blood cells from a patient, convert them into stem cells, and produce custom cell-therapy with little risk for rejection, as they are the person’s own cells.”
Alternative to antibiotics
Genes in Space-12 student investigators Isabella Chuang, left, and Julia Gross, middle, with mentor Kayleigh Ingersoll Omdahl.Genes in Space Genes in Space is a series of competitions in which students in grades 7 through 12 design DNA experiments that are flown to the space station. Genes in Space-12 examines the effects of microgravity on interactions between certain bacteria and bacteriophages, which are viruses that infect and kill bacteria. Bacteriophages already are used to treat bacterial infections on Earth.
“Boeing and miniPCR bio co-founded this competition to bring real-world scientific experiences to the classroom and promote molecular biology investigations on the space station,” said Scott Copeland of Boeing, and co-founder of Genes in Space. “This
investigation could establish a foundation for using these viruses to treat bacterial infections in space, potentially decreasing the dependence on antibiotics.”
“Previous studies indicate that bacteria may display increased growth rates and virulence in space, while the antibiotics used to combat them may be less effective,” said Dr. Ally Huang, staff scientist at miniPCR bio. “Phages produced in space could have profound implications for human health, microbial control, and the sustainability of long-duration remote missions. Phage therapy tools also could revolutionize how we manage bacterial infections and microbial ecosystems on Earth.”
Edible organisms
A purple, pre-incubation BioNutrients-3 bag, left, and a pink bag, right, which has completed incubation, on a purple and pink board used for comparison.NASA Some vitamins and nutrients in foods and supplements lose their potency during prolonged storage, and insufficient intake of even a single nutrient can lead to serious diseases, such as a vitamin C deficiency, causing scurvy. The BioNutrients-3 experiment builds on previous investigations looking at ways to produce on-demand nutrients in space using genetically engineered organisms that remain viable for years. These include yogurt and a yeast-based beverage made from yeast strains previously tested aboard station, as well as a new, engineered co-culture that produces multiple nutrients in one sample bag.
“BioNutrients-3 includes multiple food safety features, including pasteurization to kill microorganisms in the sample and a demonstration of the feasibility of using a sensor called E-Nose that simulates an ultra-sensitive nose to detect pathogens,” said Kevin Sims, project manager at NASA’s Ames Research Center in California’s Silicon Valley.
Another food safety feature is a food-grade pH indicator to track bacterial growth.
“These pH indicators help the crew visualize the progress of the yogurt and kefir samples,” Sims said. “As the organisms grow, they generate lactic acid, which lowers the pH and turns the indicator pink.”
The research also features an investigation of yogurt passage, which seeds new cultures using a bit of yogurt from a finished bag, much like maintaining a sourdough bread starter. This method could sustain a culture over multiple generations, eliminating concerns about yogurt’s shelf life during a mission to the Moon or Mars while reducing launch mass.
Understanding cell division
Cells of green algae dividing.University of Toyama The JAXA Plant Cell Division investigation examines how microgravity affects cell division in green algae and a strain of cultured tobacco cells. Cell division is a fundamental element of plant growth, but few studies have examined it in microgravity.
“The tobacco cells divide frequently, making the process easy to observe,” said Junya Kirima of JAXA. “We are excited to reveal the effects of the space environment on plant cell division and look forward to performing time-lapse live imaging of it aboard the space station.”
Understanding this process could support the development of better methods for growing plants for food in space, including on the Moon and Mars. This investigation also could provide insight to help make plant production systems on Earth more efficient.
For nearly 25 years, people have lived and worked continuously aboard the International Space Station, advancing scientific knowledge and conducting critical research for the benefit of humanity and our home planet. Space station research supports the future of human spaceflight as NASA looks toward deep space missions to the Moon under the Artemis campaign and in preparation for future human missions to Mars, as well as expanding commercial opportunities in low Earth orbit and beyond.
Learn more about the International Space Station at:
https://www.nasa.gov/station
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By Space Force
Colorado Springs is playing host to the DOD Warrior Games July 18-26, and for the first time, Guardians are among the nearly 200 wounded, ill and injured athletes competing in 11 adaptive sports over nine days.
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By NASA
The Axiom Mission 4 crew launched on June 25, 2025, aboard a SpaceX Dragon spacecraft to the International Space Station from NASA’s Kennedy Space Center in Florida. From left to right: Tibor Kapu of Hungary, ISRO (Indian Space Research Organization) astronaut Shubhanshu Shukla, former NASA astronaut Peggy Whitson, and ESA (European Space Agency) astronaut Sławosz Uznański-Wiśniewski of Poland (Credit: Axiom Space). The NASA-supported fourth private astronaut mission to the International Space Station, Axiom Mission 4, completed its flight as part of the agency’s efforts to demonstrate demand and build operational knowledge for future commercial space stations.
The four-person crew safely returned to Earth, splashing down off the coast of California at 5:31 a.m. EDT on Tuesday, aboard a SpaceX Dragon spacecraft. Teams aboard SpaceX recovery vessels retrieved the spacecraft and astronauts.
Peggy Whitson, former NASA astronaut and director of human spaceflight at Axiom Space, ISRO (Indian Space Research Organization) astronaut Shubhanshu Shukla, and ESA (European Space Agency) project astronaut Sławosz Uznański-Wiśniewski of Poland, and Hungarian to Orbit (HUNOR) astronaut Tibor Kapu of Hungary, completed about two and a half weeks in space.
The Axiom Mission 4 crew launched at 2:31 a.m. on June 25, on a Falcon 9 rocket from NASA’s Kennedy Space Center in Florida. Approximately 28 hours later, Dragon docked to the space-facing port of the space station’s Harmony module. The astronauts undocked at 7:15 a.m. on July 14, to begin the trip home.
The crew conducted microgravity research, educational outreach, and commercial activities. The spacecraft will return to Florida for inspection and processing at SpaceX’s refurbishing facilities. Throughout their mission, the astronauts conducted about 60 science experiments, and returned science, including NASA cargo, back to Earth.
A collaboration between NASA and ISRO allowed Axiom Mission 4 to deliver on a commitment highlighted by President Trump and Indian Prime Minister Narendra Modi to send the first ISRO astronaut to the station. The space agencies participated in five joint science investigations and two in-orbit science, technology, engineering, and mathematics demonstrations. NASA and ISRO have a long-standing relationship built on a shared vision to advance scientific knowledge and expand space collaboration.
The private mission also carried the first astronauts from Poland and Hungary to stay aboard the space station.
The International Space Station is a springboard for developing a low Earth orbit economy. NASA’s goal is to achieve a strong economy off the Earth where the agency can purchase services as one of many customers to meet its science and research objectives in microgravity. NASA’s commercial strategy for low Earth orbit provides the government with reliable and safe services at a lower cost, enabling the agency to focus on Artemis missions to the Moon in preparation for Mars while also continuing to use low Earth orbit as a training and proving ground for those deep space missions.
Learn more about NASA’s commercial space strategy at:
https://www.nasa.gov/commercial-space
News Media Contacts:
Claire O’Shea
Headquarters, Washington
202-358-1100
claire.a.o’shea@nasa.gov
Anna Schneider
Johnson Space Center, Houston
281-483-5111
anna.c.schneider@nasa.gov
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By Amazing Space
Massive Solar Prominence "The Beast" Threatens Eruption? Space Weather Update July 14 2025 NASA SDO
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By NASA
Teresa Sindelar always knew she wanted to be a part of human spaceflight, but she was unsure how to make that dream a reality until a chance encounter with former NASA astronaut Tom Stafford when she was 11 years old.
The pair met in a local jewelry shop near Sindelar’s Nebraska home, where Gen. Stafford was signing autographs. In addition to his photo, Gen. Stafford gave Sindelar a valuable tip – she should check out the Kansas Cosmosphere, a space museum in Hutchinson, Kansas. “I proceeded to attend every camp the Cosmosphere offered as a student, interned during college, and worked there full time while earning my graduate degree,” Sindelar said.
Official portrait of Teresa Sindelar.NASA She discovered a passion for teaching and mentoring young students through her work in the museum’s education department and a stint as a high school science teacher. When she began looking for opportunities at NASA, she sought a position that melded instruction with technical work. “I like pouring into others and watching them grow,” she said.
Today, Sindelar is a chief training officer (CTO) within the Flight Operations Directorate at NASA’s Johnson Space Center in Houston. Along with her fellow CTOs, Sindelar oversees the correct and complete training of NASA astronauts, crew members representing international partners, and all flight controllers. “I put the pieces together,” she said. “It is my job to make sure instructors, schedulers, outside partners, facility managers, and others are all in sync.” She added that CTOs have a unique position because they see the big picture of a training flow and understand the long-term training goals and objectives.
Teresa Sindelar received a 2025 Space Flight Awareness Program Honoree Award, presented by NASA astronaut Randy Bresnik.NASA “I get to do a lot of cool things and go to a lot of cool places,” she said, noting that the training facilities at Johnson and other NASA centers, as well as facilities managed by international partners, are top-notch. While she does enjoy watching astronauts work through problems and learn new systems, she has a special fondness for flight controller training and mentoring young professionals. “What fills my cup the most is seeing a brand-new employee right out of college blossom into a confident flight controller, do their job well, and make our missions better,” she said. “I like knowing that I had something to do with that.”
Sindelar has been part of the Johnson team since 2010 and worked as an educator in what was then called the center’s Office of Education and as a crew training instructor in the Space Medicine Operations Directorate before becoming a CTO. In March 2025, Sindelar received a Space Flight Awareness Program Honoree Award for her outstanding leadership in the Private Astronaut Mission (PAM) program, which is an important component of NASA’s strategy for enabling a robust and competitive commercial economy in low Earth orbit. As the lead CTO for the third PAM, Axiom Mission 3, Sindelar managed training while identifying critical inefficiencies, enhancing mission safety and performance. She spearheaded a key stakeholder retreat to streamline operations, reorganized training resources for improved accessibility, and implemented efficiency improvements that optimized mission support. Sindelar’s work was recognized during an award ceremony at NASA’s Kennedy Space Center in Florida, and she got to attend the launch of NASA’s SpaceX Crew-10 mission as a special guest.
In her 15 years with the agency, she has learned the importance of leading by example. “My team needs to see that I meet the bar I set,” she said. “Leading is about motivating your people so they are committed, not just compliant.”
Teresa Sindelar (front row, third from left) and her Space Medicine Operations crew training team with the crew members of Expedition 48.NASA Keeping a team motivated and on track is particularly important to training success and safety. “We only get a matter of months to train astronauts to do the most hazardous activities that humans have done, or to train flight controllers who literally have the mission and the lives of astronauts in their hands,” Sindelar said, adding that they cannot afford to have an unfocused or indifferent team.
Sindelar observed that Johnson’s training team is acutely aware of their responsibilities. “We live and work in the same communities as the crew members,” she said. “We see them at school functions, at the grocery store, at the park. We know their families are counting on us to bring their loved ones home safely.”
She has also learned that her voice matters. “When I was a young professional, I just never felt I could be influential, but the only person holding me back was me,” she said. “I had to learn to trust in my own instincts. That was definitely outside of my comfort zone.” She credits her mentors with helping her build confidence and knowing when and how to speak up. “I have had many giants of the spaceflight community mold and shape me in my career, from my counselors at the Cosmosphere all the way to flight directors and astronauts,” she said. “It is my privilege to learn from them, and I am grateful to each of them.”
Outside of work, Sindelar uses her voice in a different way – as part of her church choir. She also plays piano, stating that she is as passionate about music and volunteerism as she is about human spaceflight. She is a member of the Friendswood Volunteer Fire Department, as well, serving on its rehab team and as the department’s chaplain
Teresa Sindelar (second from right) and her family with a Friendswood Volunteer Fire Department fire engine. Image courtesy of Teresa Sindelar As NASA prepares to return humans to the Moon and journey on to Mars, Sindelar hopes she has taught the next generation of explorers enough so they can show the world the wonders of the universe. “This next generation will see and do things my generation never even thought of,” she said, adding that it is time for them to start leading. “Use your voice. Take care of each other along the way. Reach out and help the next one in line.”
Sindelar keeps a reminder of that important message on her desk: the picture Gen. Stafford signed all those years ago.
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