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NextSTEP Q: CIS Capability Studies III – Lunar User Terminals & Network Orchestration and Management System
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By Amazing Space
BLOOD MOON TONIGHT! Total Lunar Eclipse September 7, 2025 + 5 Amazing Moon Features You Can See!
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By NASA
NASA and Northrop Grumman are preparing to send the company’s next cargo mission to the International Space Station, flying research to support Artemis missions to the Moon and human exploration of Mars and beyond, while improving life on Earth. SpaceX’s Falcon 9 rocket will launch Northrop Grumman’s 23rd commercial resupply services mission to the orbiting laboratory.
The investigations aboard the Cygnus spacecraft aim to refine semiconductor crystals for next-generation technologies, reduce harmful microbes, improve medication production, and manage fuel pressure.
NASA, Northrop Grumman, and SpaceX are targeting launch in mid-September from Space Launch Complex 40 at Cape Canaveral Space Force Station in Florida.
Read about some of the investigations traveling to the space station:
Better semiconductor crystals
Optical micrograph of a semiconductor composite wafer with embedded semimetal phases extracted from a space grown crystal in the SUBSA facility during Mission 1United Semiconductors LLC Researchers are continuing to fine-tune in-space production of semiconductor crystals, which are critical for modern devices like cellphones and computers.
The space station’s microgravity environment could enable large-scale manufacturing of complex materials, and leveraging the orbiting platform for crystal production is expected to lead to next-generation semiconductor technologies with higher performance, chip yield, and reliability.
“Semiconductor devices fabricated using crystals from a previous mission demonstrated performance gain by a factor of two and device yield enhanced by a factor of 10 compared to Earth-based counterparts,” said Partha S. Dutta, principal investigator, United Semiconductors LLC in Los Alamitos, California.
Dutta highlighted that three independent parties validated microgravity’s benefits for growing semiconductor crystals and that the commercial value of microgravity-enhanced crystals could be worth more than $1 million per kilogram (2.2 pounds).
Space-manufactured crystals could help meet the need for radiation-hardened, low-power, high-speed electronics and sensors for space systems. They also could provide reduced power use, increased speed, and improved safety. The technology also has ground applications, including electric vehicles, waste heat recovery, and medical tools.
Learn more about the SUBSA-InSPA-SSCug experiment.
Lethal light
Germicidal Ultraviolet (UV) light is emitted by an optical fiber running through the center of an agar plateArizona State University Researchers are examining how microgravity affects ultraviolet (UV) light’s ability to prevent the formation of biofilms — communities of microbes that form in water systems. Investigators developed special optical fibers to deliver the UV light, which could provide targeted, long-lasting, and chemical-free disinfection in space and on Earth.
“In any water-based system, bacterial biofilms can form on surfaces like pipes, valves, and sensors,” said co-investigator Paul Westerhoff, a professor at Arizona State University in Tempe. “This can cause serious problems like corrosion and equipment failure, and affect human health.”
The UV light breaks up DNA in microorganisms, preventing them from reproducing and forming biofilms. Preliminary evidence suggests biofilms behave differently in microgravity, which may affect how the UV light reaches and damages bacterial DNA.
“What we’ll learn about biofilms and UV light in microgravity could help us design safer water and air systems not just for space exploration, but for hospitals, homes, and industries back on Earth,” Westerhoff said.
Learn more about the GULBI experiment.
Sowing seeds for pharmaceuticals
NASA astronaut Loral O’Hara displays the specialized sample processor used for pharmaceutical research aboard the International Space StationNASA An investigation using a specialized pharmaceutical laboratory aboard the space station examines how microgravity may alter and enhance crystal structures of drug molecules. Crystal structure can affect the production, storage, effectiveness, and administration of medications.
“We are exploring drugs with applications in cardiovascular, immunologic, and neurodegenerative disease as well as cancer,” said principal investigator Ken Savin of Redwire Space Technologies in Greenville, Indiana. “We expect microgravity to yield larger, more uniform crystals.”
Once the samples return to Earth, researchers at Purdue University in West Lafayette, Indiana, will examine the crystal structures.
The investigators hope to use the space-made crystals as seeds to produce significant numbers of crystals on Earth.
“We have demonstrated this technique with a few examples, but need to see if it works in many examples,” Savin said. “It’s like being on a treasure hunt with every experiment.”
This research also helps enhance and expand commercial use of the space station for next-generation biotechnology research and in-space production of medications.
Learn more about the ADSEP PIL-11 experiment.
Keeping fuel cool
iss0NASA astronaut Joe Acaba installs hardware for the first effort in 2017 aboard the International Space Station to test controlling pressure in cryogenic fuel tanksNASA Many spacecraft use cryogenic or extremely cold fluids as fuel for propulsion systems. These fluids are kept at hundreds of degrees below zero to remain in a liquid state, making them difficult to use in space where ambient temperatures can vary significantly. If these fluids get too warm, they turn into gas and boiloff, or slowly evaporate and escape the tank, affecting fuel efficiency and mission planning.
A current practice to prevent this uses onboard fuel to cool systems before transferring fuel, but this practice is wasteful and not feasible for Artemis missions to the Moon and future exploration of Mars and beyond. A potential alternative is using special gases that do not turn into liquids at cold temperatures to act as a barrier in the tank and control the movement of the fuel.
Researchers are testing this method to control fuel tank pressure in microgravity. It could save an estimated 42% of propellant mass per year, according to Mohammad Kassemi, a researcher at NASA’s National Center for Space Exploration Research and Case Western Reserve University in Cleveland.
The test could provide insights that help improve the design of lightweight, efficient, long-term in-space cryogenic storage systems for future deep space exploration missions.
Learn more about the ZBOT-NC experiment.
Download high-resolution photos and videos of the research highlighted in this feature.
Learn more about the research aboard the International Space Station at:
www.nasa.gov/iss-science
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3 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
The Lunar Environment Structural Test Rig simulates the intense cold of the lunar night, ranging from 40 Kelvin (K) to 125 K while maintaining a vacuum environment. This creates a tool by which scientists and engineers can test materials, electronics, and flight hardware for future Moon and Mars missions, characterizing their behaviors at these temperatures while also validating their ability to meet design requirements.
Cryogenic engineer Adam Rice tests the Lunar Environment Structural Test Rig to simulate the thermal-vacuum conditions of the lunar night on Thursday, May 22, 2025.NASA/Jef Janis Facility Overview
The Lunar Environment Structural Test Rig (LESTR) approaches the problem of creating a simulated lunar environment by departing from typical fluid immersion or jacketed-and-chilled chamber systems. It does this by using a cryocooler to reject heat and bring the test section to any point desired by the test engineer, as low as 40 K or as high as 125 K in a vacuum environment. By combining high vacuum and cryogenic temperatures, LESTR enables safe, accurate, and cost-effective testing of materials and hardware destined for the Moon and beyond. Its modular setup supports a wide range of components — from spacesuits to rover wheels to electronics — while laying the foundation for future Moon and Mars mission technologies.
Quick Facts
LESTR is a cryogenic mechanical test system built up within a conventional load frame with the goal of providing a tool to simulate the thermal-vacuum conditions of the lunar night to engineers tasked with creating the materials, tools, and machinery to succeed in NASA’s missions.
LESTR replicates extreme lunar night environments — including temperatures as low as 40 K and high vacuum (<5×10⁻⁷ Torr) — enabling true-to-space testing without liquid cryogens. Unlike traditional “wet” methods, LESTR uses a cryocooler and vacuum system to create an environment accurate to the lunar surface. From rover wheels to spacesuits to electronics, LESTR supports static and dynamic testing across a wide range of Moon and Mars mission hardware. With scalable architecture and precision thermal control, LESTR lays critical groundwork for advancing the technologies of NASA’s Artemis missions and beyond. Capabilities
Specifications
Temperature Range: 40 K to 125 K Load Capacity: ~10 kN Vacuum Level: <5×10⁻⁷ Torr Test Volume (Cold Box Dimensions): 7.5 by 9.5 by 11.5 inches Maximum Cycle Rate: 100 Hz Time to Vacuum:10⁻⁵ Torr in less than one hour 10⁻⁶ Torr in four hours Features
Dry cryogenic testing (no fluid cryogen immersion) “Dial-a-temperature” control for precise thermal conditions Integrated optical extensometer for strain imaging Digital image correlation and electrical feedthroughs support a variety of data collection methods Native support for high-duration cyclic testing Applications
Cryogenic Lifecycle Testing: fatigue, fracture, and durability assessments Low-Frequency Vibration Testing: electronics qualification for mobility systems Static Load Testing: material behavior characterization in lunar-like environments Suspension and Drivetrain Testing: shock absorbers, wheels, springs, and textiles Textiles Testing: evaluation of spacesuits and habitat fabrics Dynamic Load Testing: up to 10 kN linear capacity, 60 mm stroke Contact
Cryogenic and Mechanical Evaluation Lab Manager: Andrew Ring
216-433-9623
Andrew.J.Ring@nasa.gov
LESTR Technical Lead: Ariel Dimston
216-433-2893
Ariel.E.Dimston@nasa.gov
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NASA’s Glenn Research Center in Cleveland provides ground test facilities to industry, government, and academia. If you are considering testing in one of our facilities or would like further information about a specific facility or capability, please let us know.
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The Lunar Environment Structural Test Rig simulates the intense cold of the lunar night on Friday, June 6, 2025.NASA/Steven Logan The Lunar Environment Structural Test Rig uses a cryocooler to reject heat and bring the test section as low as 40 Kelvin in a vacuum environment on Thursday, May 22, 2025.NASA/Jef Janis Keep Exploring Discover More Topics From NASA
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By NASA
If you asked someone what they expected to see during a visit to NASA’s Johnson Space Center, they would probably list things like astronauts, engineers, and maybe a spacecraft or two. It might be a surprise to learn you can also spy hundreds of species of animals – from geckos and snakes to white-tailed deer and red-tailed hawks.
Ensuring those species and Johnson’s workforce can safely coexist is the main job of Matt Strausser, Johnson’s senior biologist for wildlife management. Strausser works to reduce the negative impacts animals can have on Johnson’s operations as well as the negative impact humans might have on native wildlife and their habitats.
NASA’s Johnson Space Center Senior Biologist Matt Strausser leads a nature hike to Johnson staff that detailed the native plant species and wildlife onsite, invasive species, and mitigation efforts.NASA/Lauren Harnett Strausser joined NASA in 2012, fresh out of graduate school, when he was hired on a six-month contract to write Johnson’s first Wildlife Management Plan. “My contract was extended a couple of times until I became a regular part of the facilities service contract, which is where I still am today,” he said.
Strausser remembers being interested in natural resources from a young age. “I spent a lot of my childhood poring through copies of National Geographic, hiking, and camping,” he said. When it was time for college, Strausser decided to study biology and natural resource management. He spent his summers in jobs or internships that mostly involved endangered wildlife species, including Attwater’s prairie chickens, which are bred at Johnson through a partnership with the Houston Zoo. Strausser noted that he conducted research across the country while he was a student, and even studied fish for a short time in the South Pacific.
“After all of those adventures in faraway places, I find it ironic that I ended up about 20 miles from where I grew up,” he said. “Once I got onsite, it did not take me long to find that this property has great remnant native plant communities, a fascinating land use history, and some unique natural resource challenges that come from the work done here. Those factors really drew me in and helped motivate me to build a career at Johnson.”
Matthew Strausser received a Silver Snoopy Award through NASA’s Space Flight Awareness Program in 2018, in recognition of his efforts to prevent and mitigate ant-inflicted damage to critical infrastructure electrical systems. From left: NASA astronaut Reid Weissman, Strausser, Strausser’s wife Kayla, NASA Acting Associate Administrator Vanessa Wyche. NASA Strausser’s work involves a variety of activities. First, he gathers data about Johnson’s wildlife populations and their habitats. “I use population counts, conflict records, satellite and aerial imagery, nest surveys, outside reports, and even historical data to get an understanding of what’s on the landscape and what problems we have to tackle,” he said.
With that information, Strausser works to engage project and facility managers and provide recommendations on how to prevent or reduce the impact of wildlife problems onsite. Strausser works with Johnson’s facilities maintenance group to modify buildings to keep animals on the outside, and he gets support from the Johnson veterinarian on animal health issues. He also works closely with Johnson’s pest control and groundskeeping contracts, as their work is often adjacent to wildlife management.
He supports the safety team, as well. “Our security contractors are a great resource for reporting wildlife issues as well as helping address them,” Strausser said, adding that some of Johnson’s safety groups “have been really helpful at getting the word out about how to stay safe around our wildlife” in coordination with the center’s internal communications team. His team also responds to wildlife conflict calls, which often involve capturing and relocating animals that have wandered into areas where they pose a risk to people or operations.
Additionally, Strausser runs the facilities contract’s small unmanned aircraft system, which uses drones to conduct facility inspections, support hurricane response, and survey on-site wildlife.
An on-site wildlife snapshot captured by the Johnson Space Center facilities contract’s small unmanned aircraft system. NASA The nature of his work has instilled in Strausser an appreciation for teamwork and collaboration among colleagues with distinct experiences. Each of the projects he works on involves team members from different organizations and contracts, and most of them do not have a background in biology. “Building a wildlife and natural resource program from the ground up and bringing all of these once-disconnected and diverse professionals together to effectively address problems – that is the achievement I take the most pride in,” he said.
Strausser observed that accomplishing the goals of the agency’s Artemis campaign will require a tremendous amount of specialized support infrastructure, and that developing and running that infrastructure will require a wide variety of professionals. “It is going to require students and specialists with all different types of backgrounds, passions, and talents.”
Overall, Strausser said he has a very dynamic job. “Wildlife issues tend to be very seasonal, so throughout the year, the types of issues I am addressing change,” he said. “On top of that, there are always new projects, problems, and questions out there that keep the work fresh and challenging.” He has learned the value of being open to new challenges and learning new skills. “Being adaptable can be just as important as mastery in a specific field,” he said.
An on-site wildlife snapshot captured by the Johnson Space Center facilities contract’s small unmanned aircraft system. NASA A Texas Longhorn relaxes onsite at Johnson Space Center, with Space Center Houston in the background.NASA Deer are plentiful on the Johnson Space Center campus.NASA A hawk perches in a tree at Johnson Space Center.NASA Attwater’s prairie chickens are bred at Johnson Space Center through a partnership with the Houston Zoo.NASA Explore More
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By NASA
3 Min Read Space Station Cell Studies
Cells grown aboard the International Space Station. Credits: University of Connecticut Science in Space August 2025
Cells are the basic building blocks of all living things, from single-celled bacteria to plants and animals containing vast numbers of them. Cells have adapted for a wide variety of settings and functions. Nerve cells in humans and animals, for example, have long, thin extensions that rapidly transmit signals, while rigid, blocky cells support the structure of plants.
Cell biology is the study of cell structure, function, and behavior. For humans, scientists in this field explore the mechanisms of diseases from bone loss to cancer and work on developing treatments.
Cell-based experiments on The International Space Station help identify how spaceflight affects people and other living systems, with applications for future space exploration and life on Earth.
JAXA astronaut Satoshi Furukawa prepares to examine cells for Cell Gravisensing in the JAXA Confocal Microscope (COSMIC).NASA Recent experiments have revealed that individual animal cells react to the effects of gravity, but how they do so is largely unknown. Cell Gravisensing, an investigation from JAXA (Japan Aerospace Exploration Agency), examines the molecular mechanism behind the ability of cells to sense gravity. Results could support development of drugs to treat muscle atrophy and osteoporosis in space and on Earth.
Cardiovascular cells
Microscopic view of cells from the lining of blood vessels cultured for the STaARS BioScience-3 experiment. University of Florida In microgravity, some astronauts experience changes in their cardiovascular system, including reduced blood volume and diminished cardiac output. An earlier investigation, STaARS Bioscience-3, examined the mechanisms behind these changes at the cellular and genetic level. The research revealed that, after only three days of spaceflight, there were changes in the expression of more than 11,000 genes in blood vessel cells that could alter their functions. The results laid the groundwork for additional research into cell response to spaceflight that could help protect the health of crew members on future missions and people with cardiovascular diseases on Earth.
Neural cells
STaARS BioScience-4 examined microgravity’s effects on neural stem cells that give rise to central nervous system cells. Researchers found changes in production and consumption of energy and increased breakdown of cellular components in these cells, responses that likely enhance adaptation to microgravity. The finding also highlights the importance of providing astronauts with sufficient energy for cognitive and physiological function on future missions.
Fish cells
A preflight image of samples and sample chambers for the Fish Scales investigation. Mitchell/Prange Goldfish scales have many of the same proteins, minerals, and cell types as the bones of mammals. The JAXA Fish Scales investigation analyzed goldfish scales exposed to three times Earth’s gravity, simulated microgravity, and microgravity on orbit. Researchers determined that goldfish scales can be used as a model to help them understand how human bones respond to spaceflight.
Mouse cells
Research with model organisms like rodents has relevance to humans in space and makes significant contributions to understanding human aging, disease, and the effects of microgravity on biological and physical processes. JAXA’s Stem Cells studied how spaceflight affected the DNA and chromosomes of embryonic mouse stem cells, and their ability to develop into adult mice after return to Earth.
Researchers analyzed unaltered cells and cells given a mutation to increase responsiveness to radiation. They found no chromosomal differences between the unaltered space-flown cells and ground controls, but the mutated cells had more DNA abnormalities. The work could enhance the understanding of radiation effects on human cancer and improve risk assessment for long-duration missions to the Moon and Mars.
NASA astronauts Drew Morgan and Christina Koch work on rodent research hardware. NASA Another study used tissue samples from RR-1, which are available through NASA’s GeneLab open data repository. Analysis showed that the heart can adapt to the stress of spaceflight in just 30 days. The researchers observed genetic changes suggesting that this adaptation may facilitate survival in space and could have applications in treating heart disease in space and on Earth.
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