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By NASA
A host of scientific investigations await the crew of NASA’s SpaceX Crew-11 mission during their long-duration expedition aboard the International Space Station. NASA astronauts Zena Cardman and Mike Fincke, and JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui, are set to study plant cell division and microgravity’s effects on bacteria-killing viruses, as well as perform experiments to produce a higher volume of human stem cells and generate on-demand nutrients.
Here are details on some of the research scheduled during the Crew-11 mission:
Making more stem cells
Cultures of stem cells grown in 2D on Earth, left, and as 3D spheres in simulated microgravity on Earth.BioServe A stem cell investigation called StemCellEx-IP1 evaluates using microgravity to produce large numbers of induced pluripotent stem cells. Made by reprogramming skin or blood cells, these stem cells can transform into any type of cell in the body and are used in regenerative medicine therapies for many diseases. However, producing enough cells on the ground is a challenge.
Researchers plan to use the microgravity environment aboard the space station to demonstrate whether generating 1,000 times more cells is possible and whether these cells are of higher quality and better for clinical use than those made on Earth. If proven, this could significantly improve future patient outcomes.
“This type of stem cell research is a chance to find treatments and maybe even cures for diseases that currently have none,” said Tobias Niederwieser of BioServe Space Technologies, which developed the investigation. “This represents an incredible potential to make life here on Earth better for all of us. We can take skin or blood cells from a patient, convert them into stem cells, and produce custom cell-therapy with little risk for rejection, as they are the person’s own cells.”
Alternative to antibiotics
Genes in Space-12 student investigators Isabella Chuang, left, and Julia Gross, middle, with mentor Kayleigh Ingersoll Omdahl.Genes in Space Genes in Space is a series of competitions in which students in grades 7 through 12 design DNA experiments that are flown to the space station. Genes in Space-12 examines the effects of microgravity on interactions between certain bacteria and bacteriophages, which are viruses that infect and kill bacteria. Bacteriophages already are used to treat bacterial infections on Earth.
“Boeing and miniPCR bio co-founded this competition to bring real-world scientific experiences to the classroom and promote molecular biology investigations on the space station,” said Scott Copeland of Boeing, and co-founder of Genes in Space. “This
investigation could establish a foundation for using these viruses to treat bacterial infections in space, potentially decreasing the dependence on antibiotics.”
“Previous studies indicate that bacteria may display increased growth rates and virulence in space, while the antibiotics used to combat them may be less effective,” said Dr. Ally Huang, staff scientist at miniPCR bio. “Phages produced in space could have profound implications for human health, microbial control, and the sustainability of long-duration remote missions. Phage therapy tools also could revolutionize how we manage bacterial infections and microbial ecosystems on Earth.”
Edible organisms
A purple, pre-incubation BioNutrients-3 bag, left, and a pink bag, right, which has completed incubation, on a purple and pink board used for comparison.NASA Some vitamins and nutrients in foods and supplements lose their potency during prolonged storage, and insufficient intake of even a single nutrient can lead to serious diseases, such as a vitamin C deficiency, causing scurvy. The BioNutrients-3 experiment builds on previous investigations looking at ways to produce on-demand nutrients in space using genetically engineered organisms that remain viable for years. These include yogurt and a yeast-based beverage made from yeast strains previously tested aboard station, as well as a new, engineered co-culture that produces multiple nutrients in one sample bag.
“BioNutrients-3 includes multiple food safety features, including pasteurization to kill microorganisms in the sample and a demonstration of the feasibility of using a sensor called E-Nose that simulates an ultra-sensitive nose to detect pathogens,” said Kevin Sims, project manager at NASA’s Ames Research Center in California’s Silicon Valley.
Another food safety feature is a food-grade pH indicator to track bacterial growth.
“These pH indicators help the crew visualize the progress of the yogurt and kefir samples,” Sims said. “As the organisms grow, they generate lactic acid, which lowers the pH and turns the indicator pink.”
The research also features an investigation of yogurt passage, which seeds new cultures using a bit of yogurt from a finished bag, much like maintaining a sourdough bread starter. This method could sustain a culture over multiple generations, eliminating concerns about yogurt’s shelf life during a mission to the Moon or Mars while reducing launch mass.
Understanding cell division
Cells of green algae dividing.University of Toyama The JAXA Plant Cell Division investigation examines how microgravity affects cell division in green algae and a strain of cultured tobacco cells. Cell division is a fundamental element of plant growth, but few studies have examined it in microgravity.
“The tobacco cells divide frequently, making the process easy to observe,” said Junya Kirima of JAXA. “We are excited to reveal the effects of the space environment on plant cell division and look forward to performing time-lapse live imaging of it aboard the space station.”
Understanding this process could support the development of better methods for growing plants for food in space, including on the Moon and Mars. This investigation also could provide insight to help make plant production systems on Earth more efficient.
For nearly 25 years, people have lived and worked continuously aboard the International Space Station, advancing scientific knowledge and conducting critical research for the benefit of humanity and our home planet. Space station research supports the future of human spaceflight as NASA looks toward deep space missions to the Moon under the Artemis campaign and in preparation for future human missions to Mars, as well as expanding commercial opportunities in low Earth orbit and beyond.
Learn more about the International Space Station at:
https://www.nasa.gov/station
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By European Space Agency
After 20 days in space, ESA project astronaut Sławosz Uznański-Wiśniewski and his Axiom Mission 4 (Ax-4) crewmates returned safely to Earth today, 15 July 2025.
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By NASA
Explore This Section Science Goddard Space Flight Center Linking Satellite Data and… Overview Learning Resources Science Activation Teams SME Map Opportunities More Science Activation Stories Citizen Science 4 min read
Linking Satellite Data and Community Knowledge to Advance Alaskan Snow Science
Seasonal snow plays a significant role in global water and energy cycles, and billions of people worldwide rely on snowmelt for water resources needs, including water supply, hydropower, agriculture, and more. Monitoring snow water equivalent (SWE) is critical for supporting these applications and for mitigating damages caused by snowmelt flooding, avalanches, and other snow-related disasters. However, our ability to measure SWE remains a challenge, particularly in northern latitudes where in situ SWE observations are sparse and satellite observations are impacted by the boreal forest and environmental conditions. Despite limited in situ SWE measurements, local residents in Arctic and sub-Arctic regions provide a vast and valuable body of place-based knowledge and observations that are essential for understanding snowpack behavior in northern regions.
As part of a joint NASA SnowEx, NASA’s Minority University Research and Education Project (MUREP) for American Indian and Alaska Native STEM (Science, Technology, Engineering, & Mathematics) Engagement (MAIANSE), and Global Learning & Observations to Benefit the Environment (GLOBE) Program partnership, a team of scientists including NASA intern Julia White (NASA Goddard Space Flight Center, University of Alaska Fairbanks), Carrie Vuyovich (NASA Goddard Space Flight Center), Alicia Joseph (NASA Goddard Space Flight Center), and Christi Buffington (University of Alaska Fairbanks, GLOBE Implementation Office) is studying snow water equivalent (SWE) across Interior Alaska. This project combines satellite-based interferometric synthetic aperture radar (InSAR) data, primarily from the Sentinel-1 satellite, with ground-based observations from the Snow Telemetry (SNOTEL) network and GLOBE (Global Learning Observations to Benefit the Environment). Together, these data sources help the team investigate how SWE varies across the landscape and how it affects local ecosystems and communities. The team is also preparing for future integration of data from NASA’s upcoming NISAR (NASA ISRO Synthetic Aperture Radar) mission, which is expected to enhance SWE retrieval capabilities.
After a collaborative visit to the classroom of Tammie Kovalenko in November 2024, Delta Junction junior and senior high school students in vocational agriculture (Vo Ag) classes, including members of Future Farmers of America (FFA), began collecting GLOBE data on a snowdrift located just outside their classroom. As the project progressed, students developed their own research questions. One student, Fianna Rooney, took the project even further — presenting research posters at both the GLOBE International Virtual Science Symposium (IVSS) and both the FFA Regional and National Conventions. Her work highlights the growing role of Alaskan youth in science, and how student-led inquiry can enrich both education and research outcomes. (This trip was funded by the NASA Science Activation Program’s Arctic and Earth SIGNs – STEM Integrating GLOBE & NASA – project at the University of Alaska Fairbanks.)
In February 2025, the team collaborated with Delta Junction Junior High and High School students, along with the Delta Junction Trails Association, to conduct a GLOBE Intensive Observation Period (IOP), “Delta Junction Snowdrifts,” to collect Landcover photos, snow depth, and snow water equivalent data. Thanks to aligned interests and research goals at the Alaska Satellite Facility (ASF), the project was further expanded into Spring 2025. Collaborators from ASF and the Alaska Center for Unmanned Aircraft Systems Integration (ACUASI) collected high resolution airborne data over the snowdrift at the Delta Junction Junior and Senior High School. This complementary dataset helped strengthen connections between satellite observations and ground-based student measurements.
This effort, led by a NASA intern, scientists, students, and Alaskan community members, highlights the power of collaboration in advancing science and education. Next steps will include collaboration with Native Alaskan communities near Delta Junction, including the Healy Lake Tribe, whose vast, generational knowledge will be of great value to deepening our understanding of Alaskan snow dynamics.
Learn more about how NASA’s Science Activation program connects NASA science experts, real content, and experiences with community leaders to do science in ways that activate minds and promote deeper understanding of our world and beyond: https://science.nasa.gov/learn/about-science-activation/
Julia White and Delta Junction student following GLOBE protocols for snow depth. Tori Brannan Share
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