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By NASA
CSA (Canadian Space Agency) astronaut Jeremy Hansen, alongside NASA astronauts Victor Glover, Reid Wiseman, and Christina Koch, will launch on the Artemis II mission early next year. The crew will participate in human research studies to provide insights about how the body performs in deep space as part of this mission. Credit: (NASA/James Blair) A sweeping collection of astronaut health studies planned for NASA’s Artemis II mission around the Moon will soon provide agency researchers with a glimpse into how deep space travel influences the human body, mind, and behavior.
During an approximately 10-day mission set to launch in 2026, NASA astronauts Reid Wiseman, Victor Glover, and Christina Koch, and CSA (Canadian Space Agency) astronaut Jeremy Hansen will collect and store their saliva, don wrist monitors that track movement and sleep, and offer other essential data for NASA’s Human Research Program and other agency science teams.
“The findings are expected to provide vital insights for future missions to destinations beyond low Earth orbit, including Mars,” said Laurie Abadie, an aerospace engineer for the program at NASA’s Johnson Space Center in Houston, who strategizes about how to carry out studies on Artemis missions. “The lessons we learn from this crew will help us to more safely accomplish deep space missions and research,” she said.
One study on the Artemis II mission, titled Immune Biomarkers, will explore how the immune system reacts to spaceflight. Another study, ARCHeR (Artemis Research for Crew Health and Readiness), will evaluate how crew members perform individually and as a team throughout the mission, including how easily they can move around within the confined space of their Orion spacecraft. Astronauts also will collect a standardized set of measurements spanning multiple physiological systems to provide a comprehensive snapshot of how spaceflight affects the human body as part of a third study called Artemis II Standard Measures. What’s more, radiation sensors placed inside the Orion capsule cells will collect additional information about radiation shielding functionality and organ-on-a-chip devices containing astronaut cells will study how deep space travel affects humans at a cellular level.
“Artemis missions present unique opportunities, and challenges, for scientific research,” said Steven Platts, chief scientist for human research at NASA Johnson.
Platts explained the mission will need to protect against challenges including exposure to higher radiation levels than on the International Space Station, since the crew will be farther from Earth.
“Together, these studies will allow scientists to better understand how the immune system performs in deep space, teach us more about astronauts’ overall well-being ahead of a Mars mission, and help scientists develop ways to ensure the health and success of crew members,” he said.
Another challenge is the relatively small quarters. The habitable volume inside Orion is about the size of a studio apartment, whereas the space station is larger than a six-bedroom house with six sleeping quarters, two bathrooms, a gym, and a 360-degree view bay window. That limitation affects everything from exercise equipment selection to how to store saliva samples.
Previous research has shown that spaceflight missions can weaken the immune system, reactivate dormant viruses in astronauts, and put the health of the crew at risk. Saliva samples from space-based missions have enabled scientists to assess various viruses, hormones, and proteins that reveal how well the immune system works throughout the mission.
But refrigeration to store such samples will not be an option on this mission due to limited space. Instead, for the Immune Biomarkers study, crew members will supply liquid saliva on Earth and dry saliva samples in space and on Earth to assess changes over time. The dry sample process involves blotting saliva onto special paper that’s stored in pocket-sized booklets.
“We store the samples in dry conditions before rehydrating and reconstituting them,” said Brian Crucian, an immunologist with NASA Johnson who’s leading the study. After landing, those samples will be analyzed by agency researchers.
For the ARCHeR study, participating crew members will wear movement and sleep monitors, called actigraphy devices, before, during, and after the mission. The monitors will enable crew members and flight controllers in mission control to study real-time health and behavioral information for crew safety, and help scientists study how crew members’ sleep and activity patterns affect overall health and performance. Other data related to cognition, behavior, and team dynamics will also be gathered before and after the mission.
“Artemis missions will be the farthest NASA astronauts have ventured into space since the Apollo era,” said Suzanne Bell, a NASA psychologist based at Johnson who is leading the investigation. “The study will help clarify key mission challenges, how astronauts work as a team and with mission control, and the usability of the new space vehicle system.”
Another human research study, Artemis II Standard Measures, will involve collecting survey and biological data before, during, and after the Artemis II mission, though blood collection will only occur before and after the mission. Collecting dry saliva samples, conducting psychological assessments, and testing head, eye, and body movements will also be part of the work. In addition, tasks will include exiting a capsule and conducting simulated moonwalk activities in a pressurized spacesuit shortly after return to Earth to investigate how quickly astronauts recover their sense of balance following a mission.
Crew members will provide data for these Artemis II health studies beginning about six months before the mission and extending for about a month after they return to Earth.
NASA also plans to use the Artemis II mission to help scientists characterize the radiation environment in deep space. Several CubeSats, shoe-box sized satellites that will be deployed into high-Earth orbit during Orion’s transit to the Moon, will probe the near-Earth and deep space radiation environment. Data gathered by these CubeSats will help scientists understand how best to shield crew and equipment from harmful space radiation at various distances from Earth.
Crew members will also keep dosimeters in their pockets that measure radiation exposure in real time. Two additional radiation-sensing technologies will also be affixed to the inside of the Orion spacecraft. One type of device will monitor the radiation environment at different shielding locations and alert crew if they need to seek shelter, such as during a solar storm. A separate collection of four radiation monitors, enabled through a partnership with the German Space Agency DLR, will be placed at various points around the cabin by the crew after launch to gather further information.
Other technologies also positioned inside the spacecraft will gather information about the potential biological effects of the deep space radiation environment. These will include devices called organ chips that house human cells derived from the Artemis II astronauts, through a project called AVATAR (A Virtual Astronaut Tissue Analog Response). After the Artemis II lands, scientists will analyze how these organ chips responded to deep space radiation and microgravity on a cellular level.
Together, the insights from all the human research science collected through this mission will help keep future crews safe as humanity extends missions to the Moon and ventures onward to Mars.
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NASA’s Human Research Program
NASA’s Human Research Program pursues methods and technologies to support safe, productive human space travel. Through science conducted in laboratories, ground-based analogs, commercial missions, the International Space Station and Artemis missions, the program scrutinizes how spaceflight affects human bodies and behaviors. Such research drives the program’s quest to innovate ways that keep astronauts healthy and mission ready as human space exploration expands to the Moon, Mars, and beyond.
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By Space Force
The Department of the Air Force is aligning with a new federal initiative to overhaul how government services are designed and delivered, a move leaders say will sharpen warfighting readiness, increase lethality and save taxpayer dollars.
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By NASA
NASA’s Human Lander Challenge (HuLC) is an initiative supporting its Exploration Systems Development Mission Directorate’s (ESDMD’s) efforts to explore innovative solutions for a variety of known technology development areas for human landing systems (HLS). Landers are used to safely ferry astronauts to and from the lunar surface as part of the mission architecture for NASA’s Artemis campaign. Through this challenge, college students contribute to the advancement of HLS technologies, concepts, and approaches. Improvements in these technology areas have the potential to revolutionize NASA’s approach to space exploration, and contributions from the academic community are a valuable part of the journey to discovery. HuLC is open to teams comprised of full-time or part-time undergraduate and/or graduate students at an accredited U.S.-based community college, college, or university. HuLC projects allow students to incorporate their coursework into real aerospace design concepts and work together in a team environment. Interdisciplinary teams are encouraged.
Award: $126,000 in total prizes
Open Date: August 29, 2025
Close Date: March 4, 2026
For more information, visit: https://hulc.nianet.org/
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By NASA
Credit: NASA NASA has awarded ASCEND Aerospace & Technology of Cape Canaveral, Florida, the Contract for Organizing Spaceflight Mission Operations and Systems (COSMOS), to provide services at the agency’s Johnson Space Center in Houston.
The COSMOS is a single award, indefinite-delivery/indefinite-quantity contract valued at $1.8 billion that begins its five-year base period no earlier than Dec. 1, with two option periods that could extend until 2034. The Aerodyne Company of Cape Canaveral, Florida, and Jacobs Technology Company of Tullahoma, Tennessee, are joint venture partners.
Work performed under the contract will support NASA’s Flight Operation Directorate including the Orion and Space Launch System Programs, the International Space Station, Commercial Crew Program, and the Artemis campaign. Services include Mission Control Center systems, training systems, mockup environments, and training for astronauts, instructors, and flight controllers.
For more information about NASA and agency programs, visit:
https://www.nasa.gov
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Tiernan Doyle
Headquarters, Washington
202-358-1600
tiernan.doyle@nasa.gov
Chelsey Ballarte
Johnson Space Center, Houston
281-483-5111
chelsey.n.ballarte@nasa.gov
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Last Updated Aug 28, 2025 LocationNASA Headquarters Related Terms
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By NASA
3 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
Human-rating is a critical certification process that validates the safety, reliability, and suitability of space systems—including orbiters, launch vehicles, rovers, spacesuits, habitats, and other crewed elements—for human use and interaction. This process ensures that systems are designed not only to protect human life but also to accommodate human needs and effectively integrate human capabilities. Human-rating requires that systems can tolerate failures, provide life-sustaining environments, and offer the crew sufficient control and situational awareness. NASA’s standards, such as a maximum allowable probability of loss of crew of 1 in 500 for ascent or descent, reflect the agency’s commitment to minimizing risk in human spaceflight.
Over the decades, the concept of human-rating has evolved significantly. Early efforts focused primarily on basic crew survival and redundancy in critical systems. However, as missions became more complex and extended in duration, the scope of human-rating expanded to include human performance, health management, and the psychological and physiological demands of space travel. Today, human-rating is a multidisciplinary effort that integrates engineering, medical, and operational expertise to ensure that systems are not only survivable but also support optimal human function in extreme environments.
Modern human-rating standards—such as NASA Procedural Requirements (NPR) 8705.2C, NASA-STD-8719.29 (Technical Requirements for Human-Rating), and NASA-STD-3001 (Human System Standards)—form the foundation of NASA’s approach. These documents emphasize risk-informed design, fault tolerance, human factors engineering, and the ability to recover from hazardous situations. They also provide detailed guidance on system safety, crew control interfaces, abort capabilities, and environmental health requirements. Together, they ensure that human spaceflight systems are designed to accommodate, utilize, and protect the crew throughout all mission phases.
The human-rating certification process is rigorous and iterative. It involves extensive testing, validation, and verification of system performance, including simulations, flight tests, and integrated safety analyses. Certification also requires continuous monitoring, configuration control, and maintenance to ensure that systems remain in their certified state throughout their operational life. Importantly, human-rating is not just a checklist of technical requirements—it represents a cultural commitment to crew safety. It fosters a mindset in which every team member, from design engineers to mission operators, shares responsibility for protecting human life.
To support program and project teams in applying these standards, NASA has conducted cross-reviews of documents like NASA-STD-3001 in relation to NASA-STD-8719.29. These assessments help identify relevant human health and performance requirements that should be considered during system design and development. While not a substitute for detailed applicability assessments, such reviews provide valuable guidance for integrating human-rating principles into mission planning and vehicle architecture.
NASA/Sydney Bergen-Hill Read More About Human Rating Share
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Last Updated Aug 15, 2025 Related Terms
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