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By NASA
CSA (Canadian Space Agency) astronaut Jeremy Hansen, alongside NASA astronauts Victor Glover, Reid Wiseman, and Christina Koch, will launch on the Artemis II mission early next year. The crew will participate in human research studies to provide insights about how the body performs in deep space as part of this mission. Credit: (NASA/James Blair) A sweeping collection of astronaut health studies planned for NASA’s Artemis II mission around the Moon will soon provide agency researchers with a glimpse into how deep space travel influences the human body, mind, and behavior.
During an approximately 10-day mission set to launch in 2026, NASA astronauts Reid Wiseman, Victor Glover, and Christina Koch, and CSA (Canadian Space Agency) astronaut Jeremy Hansen will collect and store their saliva, don wrist monitors that track movement and sleep, and offer other essential data for NASA’s Human Research Program and other agency science teams.
“The findings are expected to provide vital insights for future missions to destinations beyond low Earth orbit, including Mars,” said Laurie Abadie, an aerospace engineer for the program at NASA’s Johnson Space Center in Houston, who strategizes about how to carry out studies on Artemis missions. “The lessons we learn from this crew will help us to more safely accomplish deep space missions and research,” she said.
One study on the Artemis II mission, titled Immune Biomarkers, will explore how the immune system reacts to spaceflight. Another study, ARCHeR (Artemis Research for Crew Health and Readiness), will evaluate how crew members perform individually and as a team throughout the mission, including how easily they can move around within the confined space of their Orion spacecraft. Astronauts also will collect a standardized set of measurements spanning multiple physiological systems to provide a comprehensive snapshot of how spaceflight affects the human body as part of a third study called Artemis II Standard Measures. What’s more, radiation sensors placed inside the Orion capsule cells will collect additional information about radiation shielding functionality and organ-on-a-chip devices containing astronaut cells will study how deep space travel affects humans at a cellular level.
“Artemis missions present unique opportunities, and challenges, for scientific research,” said Steven Platts, chief scientist for human research at NASA Johnson.
Platts explained the mission will need to protect against challenges including exposure to higher radiation levels than on the International Space Station, since the crew will be farther from Earth.
“Together, these studies will allow scientists to better understand how the immune system performs in deep space, teach us more about astronauts’ overall well-being ahead of a Mars mission, and help scientists develop ways to ensure the health and success of crew members,” he said.
Another challenge is the relatively small quarters. The habitable volume inside Orion is about the size of a studio apartment, whereas the space station is larger than a six-bedroom house with six sleeping quarters, two bathrooms, a gym, and a 360-degree view bay window. That limitation affects everything from exercise equipment selection to how to store saliva samples.
Previous research has shown that spaceflight missions can weaken the immune system, reactivate dormant viruses in astronauts, and put the health of the crew at risk. Saliva samples from space-based missions have enabled scientists to assess various viruses, hormones, and proteins that reveal how well the immune system works throughout the mission.
But refrigeration to store such samples will not be an option on this mission due to limited space. Instead, for the Immune Biomarkers study, crew members will supply liquid saliva on Earth and dry saliva samples in space and on Earth to assess changes over time. The dry sample process involves blotting saliva onto special paper that’s stored in pocket-sized booklets.
“We store the samples in dry conditions before rehydrating and reconstituting them,” said Brian Crucian, an immunologist with NASA Johnson who’s leading the study. After landing, those samples will be analyzed by agency researchers.
For the ARCHeR study, participating crew members will wear movement and sleep monitors, called actigraphy devices, before, during, and after the mission. The monitors will enable crew members and flight controllers in mission control to study real-time health and behavioral information for crew safety, and help scientists study how crew members’ sleep and activity patterns affect overall health and performance. Other data related to cognition, behavior, and team dynamics will also be gathered before and after the mission.
“Artemis missions will be the farthest NASA astronauts have ventured into space since the Apollo era,” said Suzanne Bell, a NASA psychologist based at Johnson who is leading the investigation. “The study will help clarify key mission challenges, how astronauts work as a team and with mission control, and the usability of the new space vehicle system.”
Another human research study, Artemis II Standard Measures, will involve collecting survey and biological data before, during, and after the Artemis II mission, though blood collection will only occur before and after the mission. Collecting dry saliva samples, conducting psychological assessments, and testing head, eye, and body movements will also be part of the work. In addition, tasks will include exiting a capsule and conducting simulated moonwalk activities in a pressurized spacesuit shortly after return to Earth to investigate how quickly astronauts recover their sense of balance following a mission.
Crew members will provide data for these Artemis II health studies beginning about six months before the mission and extending for about a month after they return to Earth.
NASA also plans to use the Artemis II mission to help scientists characterize the radiation environment in deep space. Several CubeSats, shoe-box sized satellites that will be deployed into high-Earth orbit during Orion’s transit to the Moon, will probe the near-Earth and deep space radiation environment. Data gathered by these CubeSats will help scientists understand how best to shield crew and equipment from harmful space radiation at various distances from Earth.
Crew members will also keep dosimeters in their pockets that measure radiation exposure in real time. Two additional radiation-sensing technologies will also be affixed to the inside of the Orion spacecraft. One type of device will monitor the radiation environment at different shielding locations and alert crew if they need to seek shelter, such as during a solar storm. A separate collection of four radiation monitors, enabled through a partnership with the German Space Agency DLR, will be placed at various points around the cabin by the crew after launch to gather further information.
Other technologies also positioned inside the spacecraft will gather information about the potential biological effects of the deep space radiation environment. These will include devices called organ chips that house human cells derived from the Artemis II astronauts, through a project called AVATAR (A Virtual Astronaut Tissue Analog Response). After the Artemis II lands, scientists will analyze how these organ chips responded to deep space radiation and microgravity on a cellular level.
Together, the insights from all the human research science collected through this mission will help keep future crews safe as humanity extends missions to the Moon and ventures onward to Mars.
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NASA’s Human Research Program
NASA’s Human Research Program pursues methods and technologies to support safe, productive human space travel. Through science conducted in laboratories, ground-based analogs, commercial missions, the International Space Station and Artemis missions, the program scrutinizes how spaceflight affects human bodies and behaviors. Such research drives the program’s quest to innovate ways that keep astronauts healthy and mission ready as human space exploration expands to the Moon, Mars, and beyond.
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By NASA
A child of the Space Shuttle Program, Jeni Morrison grew up walking the grounds of NASA’s Johnson Space Center in Houston with her parents and listening to family stories about human spaceflight.
Now, with more than 15 years at NASA, Morrison serves as one of Johnson’s Environmental Programs managers. She ensures the center complies with laws that protect its resources by overseeing regulatory compliance for cultural and natural resources, stormwater and drinking water programs, and the National Environmental Policy Act. She also safeguards Johnson’s historic legacy as Johnson’s Cultural Resources manager.
Jeni Morrison in the mall area at NASA’s Johnson Space Center in Houston, where employees often see local wildlife, including turtles, birds, deer, and the occasional alligator. “I make sure our actions comply with the National Historic Preservation act, since the center is considered a historic district with two National Historic Landmarks onsite,” Morrison said. “I make sure we respect and document Johnson’s heritage while paving the way for new efforts and mission objectives.”
Morrison takes pride in finding solutions that increase efficiency while protecting resources. One example was a project with Johnson’s Geographic Information System team to create an interactive material and chemical spill plan map. The new system helps responders quickly trace spill paths above and underground to deploy resources faster, reducing cleanup costs and minimizing environmental impacts.
“Every improvement we make not only saves time and resources, but strengthens our ability to support NASA’s mission,” she said.
By the very nature of our work, NASA makes history all the time. That history is important for all people, both to remember the sacrifices and accomplishments of so many, but also to ensure we don’t repeat mistakes as we strive for even bolder achievements.
Jeni Morrison
Environmental Program Manager
Jeni Morrison presents an overview of environmental compliance and center initiatives to employees at NASA’s Johnson Space Center in 2014. NASA/Lauren Harnett For Morrison, success often comes down to teamwork. She has learned to adapt her style to colleagues’ needs to strengthen collaboration.
“By making the effort to accommodate others’ communication styles and learn from different perspectives, we create better, more efficient work,” she said. “Thankfully, so many people here at NASA are willing to teach and to share their experiences.”
Her message to the Artemis Generation is simple: Always keep learning!
“You never know when a side conversation could give you an answer to a problem you are facing down the line,” she said. “You must be willing to ask questions and learn something new to find those connections.”
Jeni Morrison (second from right) with the Biobased Coolant Project Team at NASA’s Johnson Space Center in 2018. The team tested biobased metalworking coolants and identified a product that outperformed petroleum-based options, meeting flight hardware specifications while reducing waste disposal costs and labor hours. Even as a young child visiting NASA Johnson, I could feel the sense of adventure, accomplishment, and the drive to reach new heights of human capability. I realize that those experiences gave me a fascination with learning and an inherent need to find ways to do things better.
jENI mORRISON
Environmental Program Manager
Her passion for learning and discovery connects to a family tradition at NASA. Her grandfather contributed to multiple Apollo missions, including helping solve the oxygen tank malfunction on Apollo 13. Her mother worked at the center transcribing astronaut recordings and writing proposals, and her father flew experiments aboard the space shuttle and International Space Station. Morrison’s sister and extended family also worked at Johnson.
Now her son is growing up on the center grounds while attending the JSC Child Care Center. “As the fourth generation to be at Johnson, he is already talking about how he loves science and can’t wait to do his own experiments,” she said.
For Morrison, carrying that family legacy forward through environmental stewardship is a privilege. “Being able to contribute to NASA’s mission through environmental compliance feels like the best of both worlds for me,” Morrison said. “It combines my love of science and NASA with my drive to find more efficient ways to operate while protecting this incredible site and everything it represents.”
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By NASA
NASA’s Human Lander Challenge (HuLC) is an initiative supporting its Exploration Systems Development Mission Directorate’s (ESDMD’s) efforts to explore innovative solutions for a variety of known technology development areas for human landing systems (HLS). Landers are used to safely ferry astronauts to and from the lunar surface as part of the mission architecture for NASA’s Artemis campaign. Through this challenge, college students contribute to the advancement of HLS technologies, concepts, and approaches. Improvements in these technology areas have the potential to revolutionize NASA’s approach to space exploration, and contributions from the academic community are a valuable part of the journey to discovery. HuLC is open to teams comprised of full-time or part-time undergraduate and/or graduate students at an accredited U.S.-based community college, college, or university. HuLC projects allow students to incorporate their coursework into real aerospace design concepts and work together in a team environment. Interdisciplinary teams are encouraged.
Award: $126,000 in total prizes
Open Date: August 29, 2025
Close Date: March 4, 2026
For more information, visit: https://hulc.nianet.org/
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By NASA
Advancing Single-Photon Sensing Image Sensors to Enable the Search for Life Beyond Earth
A NASA-sponsored team is advancing single-photon sensing Complementary Metal-Oxide-Semiconductor (CMOS) detector technology that will enable future NASA astrophysics space missions to search for life on other planets. As part of their detector maturation program, the team is characterizing sensors before, during, and after high-energy radiation exposure; developing novel readout modes to mitigate radiation-induced damage; and simulating a near-infrared CMOS pixel prototype capable of detecting individual photons.
Single-photon sensing and photon-number resolving CMOS image sensors: a 9.4 Mpixel sensor (left) and a 16.7 Mpixel sensor (right). Credit: CfD, RIT Are we alone in the universe? This age-old question has inspired scientific exploration for centuries. If life on other planets evolves similarly to life on Earth, it can imprint its presence in atmospheric spectral features known asbiosignatures. They include absorption and emission lines in the spectrum produced by oxygen, carbon dioxide, methane, and other molecules that could indicate conditions which can support life. A future NASA astrophysics mission, the Habitable Worlds Observatory (HWO), will seek to find biosignatures in the ultraviolet, optical, and near-infrared (NIR) spectra of exoplanet atmospheres to look for evidence that life may exist elsewhere in the universe.
HWO will need highly sensitive detector technology to detect these faint biosignatures on distant exoplanets. The Single-Photon Sensing Complementary Metal-Oxide-Semiconductor (SPSCMOS) image sensor is a promising technology for this application. These silicon-based sensors can detect and resolve individual optical-wavelength photons using a low-capacitance, high-gain floating diffusion sense node. They operate effectively over a broad temperature range, including at room temperature. They have near-zero read noise, are tolerant to radiation, and generate very little unwanted signal—such as dark current. When cooled to 250 K, the dark current drops to just one electron every half-hour. If either the read noise or dark current is too high, the sensor will fail to detect the faint signals that biosignatures produce.
A research team at the Rochester Institute of Technology (RIT) Center for Detectors (CfD) is accelerating the readiness of these SPSCMOS sensors for use in space missions through detector technology maturation programs funded by NASA’s Strategic Astrophysics Technology and Early Stage Innovations solicitations. These development programs include several key goals:
Characterize critical detector performance metrics like dark current, quantum efficiency, and read noise before, during, and after exposure to high-energy radiation Develop new readout modes for these sensors to mitigate effects from short-term and long-term radiation damage Design a new NIR version of the sensor using Technology Computer-Aided Design (TCAD) software SPSCMOS sensors operate similarly to traditional CMOS image sensors but are optimized to detect individual photons—an essential capability for ultra-sensitive space-based observations, such as measuring the gases in the atmospheres of exoplanets. Incoming photons enter the sensor and generate free charges (electrons) in the sensor material. These charges collect in a pixel’s storage well and eventually transfer to a low-capacitance component called the floating diffusion (FD) sense node where each free charge causes a large and resolved voltage shift. This voltage shift is then digitized to read the signal.
Experiments that measure sensor performance in a space relevant environment use a vacuum Dewar and a thermally-controlled mount to allow precise tuning of the sensors temperature. The Dewar enables testing at conditions that match the expected thermal environment of the HWO instrument, and can even cool the sensor and its on-chip circuits to temperatures colder than any prior testing reported for this detector family. These tests are critical for revealing performance limitations with respect to detector metrics like dark current, quantum efficiency, and read noise. As temperatures change, the electrical properties of on-chip circuits can also change, which affects the read out of charge in a pixel.
The two figures show results for SPSCMOS devices. The figure on the left shows a photon counting histogram with peaks that correspond to photon number. The figure on the right shows the dark current for a SPSCMOS device before and after exposure to 50 krad of 60 MeV protons. Credit: CfD, RIT The radiation-rich environment for HWO will cause temporary and permanent effects in the sensor. These effects can corrupt the signal measured in a pixel, interrupt sensor clocking and digital logic, and can cause cumulative damage that gradually degrades sensor performance. To mitigate the loss of detector sensitivity throughout a mission lifetime, the RIT team is developing new readout modes that are not available in commercial CMOS sensors. These custom modes sample the signal over time (a “ramp” acquisition) to enable the detection and removal of cosmic ray artifacts. In one mode, when the system identifies an artifact, it segments the signal ramp and selectively averages the segments to reconstruct the original signal—preserving scientific data that would otherwise be lost. In addition, a real-time data acquisition system monitors the detector’s power consumption, which may change from the accumulation of damage throughout a mission. The acquisition system records these shifts and communicates with the detector electronics to adjust voltages and maintain nominal operation. These radiation damage mitigation strategies will be evaluated during a number of test programs at ground-based radiation facilities. The tests will help identify unique failure mechanisms that impact SPSCMOS technology when it is exposed to radiation equivalent to the dose expected for HWO.
Custom acquisition electronics (left) that will control the sensors during radiation tests, and an image captured using this system (right). Credit: CfD, RIT While existing SPSCMOS sensors are limited to detecting visible light due to their silicon-based design, the RIT team is developing the world’s first NIR single-photon photodiode based on the architecture used in the optical sensors. The photodiode design starts as a simulation in TCAD software to model the optical and electrical properties of the low-capacitance CMOS architecture. The model simulates light-sensitive circuits using both silicon and Mercury Cadmium Telluride (HgCdTe or MCT) material to determine how well the pixel would measure photo-generated charge if a semiconductor foundry physically fabricated it. It has 2D and 3D device structures that convert light into electrical charge, and circuits to control charge transfer and signal readout with virtual probes that can measure current flow and electric potential. These simulations help to evaluate the key mechanisms like the conversion of light into electrons, storing and transferring the electrons, and the output voltage of the photodiode sampling circuit.
In addition to laboratory testing, the project includes performance evaluations at a ground-based telescope. These tests allow the sensor to observe astronomical targets that cannot be fully replicated in lab. Star fields and diffuse nebulae challenge the detector’s full signal chain under real sky backgrounds with faint flux levels, field-dependent aberrations, and varying seeing conditions. These observations help identify performance limitations that may not be apparent in controlled laboratory measurements.
In January 2025, a team of researchers led by PhD student Edwin Alexani used an SPSCMOS-based camera at the C.E.K. Mees Observatory in Ontario County, New York. They observed star cluster M36 to evaluate the sensor’s photometric precision, and the Bubble Nebula in a narrow-band H-alpha filter. The measured dark current and read noise were consistent with laboratory results.
The team observed photometric reference stars to estimate the quantum efficiency (QE) or the ability for the detector to convert photons into signal. The calculated QE agreed with laboratory measurements, despite differences in calibration methods.
The team also observed the satellite STARLINK-32727 as it passed through the telescope’s field of view and measured negligible persistent charge—residual signal that can remain in detector pixels after exposure to a bright source. Although the satellite briefly produced a bright streak across several pixels due to reflected sunlight, the average latent charge in affected pixels was only 0.03 e–/pix – well below both the sky-background and sensor’s read noise.
Images captured at the C.E.K. Mees Observatory. Left: The color image shows M36 in the Johnson color filters B (blue), V (green), and R (red) bands (left). Right: Edwin Alexani and the SPSCMOS camera (right). Credit: : CfD, RIT As NASA advances and matures the HWO mission, SPSCMOS technology promises to be a game-changer for exoplanet and general astrophysics research. These sensors will enhance our ability to detect and analyze distant worlds, bringing us one step closer to answering one of humanity’s most profound questions: are we alone?
For additional details, see the entry for this project on NASA TechPort.
Project Lead(s): Dr. Donald F. Figer, Future Photon Initiative and Center for Detectors, Rochester Institute of Technology (RIT), supported by engineer Justin Gallagher and a team of students.
Sponsoring Organization(s): NASA Astrophysics Division, Strategic Astrophysics Technology (SAT) Program and NASA Space Technology Mission Directorate (STMD), Early Stage Innovations (ESI) Program
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Last Updated Sep 02, 2025 Related Terms
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By NASA
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Preparations for Next Moonwalk Simulations Underway (and Underwater)
Human-rating is a critical certification process that validates the safety, reliability, and suitability of space systems—including orbiters, launch vehicles, rovers, spacesuits, habitats, and other crewed elements—for human use and interaction. This process ensures that systems are designed not only to protect human life but also to accommodate human needs and effectively integrate human capabilities. Human-rating requires that systems can tolerate failures, provide life-sustaining environments, and offer the crew sufficient control and situational awareness. NASA’s standards, such as a maximum allowable probability of loss of crew of 1 in 500 for ascent or descent, reflect the agency’s commitment to minimizing risk in human spaceflight.
Over the decades, the concept of human-rating has evolved significantly. Early efforts focused primarily on basic crew survival and redundancy in critical systems. However, as missions became more complex and extended in duration, the scope of human-rating expanded to include human performance, health management, and the psychological and physiological demands of space travel. Today, human-rating is a multidisciplinary effort that integrates engineering, medical, and operational expertise to ensure that systems are not only survivable but also support optimal human function in extreme environments.
Modern human-rating standards—such as NASA Procedural Requirements (NPR) 8705.2C, NASA-STD-8719.29 (Technical Requirements for Human-Rating), and NASA-STD-3001 (Human System Standards)—form the foundation of NASA’s approach. These documents emphasize risk-informed design, fault tolerance, human factors engineering, and the ability to recover from hazardous situations. They also provide detailed guidance on system safety, crew control interfaces, abort capabilities, and environmental health requirements. Together, they ensure that human spaceflight systems are designed to accommodate, utilize, and protect the crew throughout all mission phases.
The human-rating certification process is rigorous and iterative. It involves extensive testing, validation, and verification of system performance, including simulations, flight tests, and integrated safety analyses. Certification also requires continuous monitoring, configuration control, and maintenance to ensure that systems remain in their certified state throughout their operational life. Importantly, human-rating is not just a checklist of technical requirements—it represents a cultural commitment to crew safety. It fosters a mindset in which every team member, from design engineers to mission operators, shares responsibility for protecting human life.
To support program and project teams in applying these standards, NASA has conducted cross-reviews of documents like NASA-STD-3001 in relation to NASA-STD-8719.29. These assessments help identify relevant human health and performance requirements that should be considered during system design and development. While not a substitute for detailed applicability assessments, such reviews provide valuable guidance for integrating human-rating principles into mission planning and vehicle architecture.
NASA/Sydney Bergen-Hill Read More About Human Rating Share
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Last Updated Aug 15, 2025 Related Terms
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