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By NASA
While it may sound like the opening to a punchline, this scientific question was at the heart of a research experiment that orbited the Moon aboard Artemis I.NASA astronaut and Expedition 65 Flight Engineer Mark Vande Hei caring for chili peppers aboard the International Space Station. NASA New research uncovers the connection between space agriculture and astronaut health. A study published in npj Microgravity shows how analyzing diverse datasets together can reveal insights that might otherwise be missed — in this case, linking space-grown food quality to astronaut nutrition and gut health.
The paper reviewed previous studies of plants grown aboard the International Space Station. The authors found that some edible plants grown in low Earth orbit have lower concentrations of essential nutrients, like calcium and magnesium, than those grown on Earth.
The reduced levels of these nutrients could make crops not as effective in mitigating the bone loss and reduced immune function that astronauts encounter in space.
Working Groups Uncover Hidden Health Connections
Three Analysis Working Groups from NASA’s Open Science Data Repository collaborated to make this paper possible. These discipline-specific groups typically work independently, but this project sparked conversations among researchers with different specialties.
Researchers combined plant data, crop nutrition profiles, gut studies, and astronaut blood biomarkers — a data integration effort of the Biological and Physical Sciences Division open science model. The work also draws on data from JAXA (Japan Aerospace Exploration Agency).
For NASA, these findings offer new insights into how to feed and support astronauts in space, particularly on long-duration missions to the Moon and Mars.
Seeks Ways to Improve Space Diets
The study also examined increased intestinal permeability — often called “leaky gut” — a condition that can result from poor nutrition and may be exacerbated by the space environment. Intestinal permeability may interfere with how astronauts absorb nutrients and regulate immune responses.
If properly engineered, space-grown crops could offer a solution to these health challenges. The team outlined several potential strategies, including bioengineering plants with higher nutrient content, incorporating more antioxidant-rich species, and designing personalized nutrition plans using astronauts’ genetic information.
The study suggests targeting specific biological pathways, such as using compounds like quercetin, an antioxidant found in certain crops, to address bone health challenges at the molecular level. The approach emphasizes designing nutrition plans based on individual astronaut physiology, including how well their digestive systems can absorb nutrients.
Related Resources
Open Science Data Repository
Open Science Data Repository Analysis Working Groups (AWG)
About BPS
NASA’s Biological and Physical Sciences Division pioneers scientific discovery and enables exploration by using space environments to conduct investigations not possible on Earth. Studying biological and physical phenomenon under extreme conditions allows researchers to advance the fundamental scientific knowledge required to go farther and stay longer in space, while also benefitting life on Earth.
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By NASA
Credit: NASA NASA has selected KBR Wyle Services, LLC of Fulton, Maryland, to provide services to the Human Health and Performance Directorate at the agency’s Johnson Space Center in Houston, which focuses on astronaut health, occupational health, and research that could help mitigate health risks for future human spaceflight missions.
The Human Health and Performance Contract 2 is a follow-on single-award indefinite-delivery/indefinite-quantity contract that begins its five-year period of performance on Nov. 1, with two possible option periods that could extend it through 2035. The total estimated value of the base period plus the optional periods is $3.6 billion. Leidos, Inc. of Reston, Virginia, is a subcontractor.
The contract will acquire support services for several programs, primarily at NASA Johnson. This includes the Human Research Program, International Space Station Program, Commercial Crew Program, Artemis campaign, and more. Services include ensuring crew health, safety, and performance; providing occupational health services; and conducting research into mitigating risks to the health, safety, and performance of future spaceflight crews.
The Human Health and Performance Directorate leads the global spaceflight community in protecting astronaut health and enabling human mission performance. Its vision focuses on humans living, working, and thriving in space, on the Moon and on to Mars, and its mission is to lead the global spaceflight community in protecting astronaut health and enabling human mission performance.
For more information about NASA and agency programs, visit:
https://www.nasa.gov
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Tiernan Doyle
Headquarters, Washington
202-358-1600
tiernan.doyle@nasa.gov
Victoria Segovia
Johnson Space Center, Houston
281-483-5111
victoria.segovia@nasa.gov
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Last Updated Aug 11, 2025 LocationNASA Headquarters Related Terms
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By NASA
The crew of NASA’s SpaceX Crew-11 mission sit inside a Dragon training spacecraft at SpaceX in Hawthorne, California. Pictured from left: Roscosmos cosmonaut Oleg Platonov, NASA astronauts Mike Fincke and Zena Cardman, and JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui (Credit: SpaceX). NASA’s SpaceX Crew-11 mission is set to launch a four-person crew to the International Space Station later this summer. Some of the crew have volunteered to participate in a series of experiments to address health challenges astronauts may face on deep space missions during NASA’s Artemis campaign and future human expeditions to Mars.
The research during Crew-11 includes simulated lunar landings, tactics to safeguard vision, and other human physiology studies led by NASA’s Human Research Program.
Select crew members will participate in a series of simulated Moon landings, before, during, and after their flight. Using a handheld controller and multiple screens, the astronauts will fly through simulated scenarios created to resemble the lunar South Pole region that Artemis crews plan to visit. This experiment allows researchers to evaluate how different gravitational forces may disorient astronauts and affect their ability to pilot a spacecraft, like a lunar lander.
“Even though many landing tasks are automated, astronauts must still know how to monitor the controls and know when to take over to ensure a safe landing,” said Scott Wood, a neuroscientist at NASA’s Johnson Space Center in Houston coordinating the scientific investigation. “Our study assesses exactly how changes in gravity affect spatial awareness and piloting skills that are important for navigating these scenarios.”
A ground control group completing the same tasks over a similar timeframe will help scientists better understand gravitational effects on human performance. The experiment’s results could inform the pilot training needed for future Artemis crews.
“Experiencing weightlessness for months and then feeling greater levels of gravity on a planet like Mars, for example, may increase the risk of disorientation,” said Wood. “Our goal is to help astronauts adapt to any gravitational change, whether it’s to the Moon, a new planet, or landing back on Earth.”
Other studies during the mission will explore possible ways to treat or prevent a group of eye and brain changes that can occur during long-duration space travel, called spaceflight associated neuro-ocular syndrome (SANS).
Some researchers suspect the redistribution of bodily fluids in constant weightlessness may increase pressure in the head and contribute to SANS. One study will investigate fluid pressure on the brain while another will examine how the body processes B vitamins and whether supplements can affect how astronauts respond to bodily fluid shifts. Participating crew members will test whether a daily B vitamin supplement can eliminate or ease symptoms of SANS. Specific crew members also will wear thigh cuffs to keep bodily fluids from traveling headward.
Crew members also will complete another set of experiments, called CIPHER (Complement of Integrated Protocols for Human Exploration Research), which measures how multiple systems within the human body change in space. The study includes vision assessments, MRI scans, and other medical exams to provide a complete overview of the whole body’s response to long-duration spaceflight.
Several other studies involving human health and performance are also a part of Crew-11’s science portfolio. Crew members will contribute to a core set of measurements called Spaceflight Standard Measures, which collects physical data and biological samples from astronauts and stores them for other comparative studies. Participants will supply biological samples, such as blood and urine, for a study characterizing how spaceflight alters astronauts’ genetic makeup. In addition, volunteers will test different exercise regimens to help scientists explore what activities remain essential for long-duration journeys.
After landing, participating crew members will complete surveys to track any discomfort, such as scrapes or bruises, acquired from re-entry. The data will help clarify whether mission length increases injury risks and could help NASA design landing systems on future spacecraft as NASA prepares to travel to the Moon, Mars, and beyond.
NASA’s Human Research Program pursues methods and technologies to support safe, productive human space travel. Through science conducted in laboratories, ground-based analogs, and aboard the International Space Station, the program investigates how spaceflight affects human bodies and behaviors. Such research drives NASA’s quest to innovate ways that keep astronauts healthy and mission-ready.
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By Space Force
The Department of the Air Force launched its Pacific-focused first-in-a-generation Department-Level Exercise series today in multiple locations across the United States and Indo-Pacific areas of responsibility.
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By Space Force
Ahead of the movie's theatrical release, Disney/Pixar invited military families to special screenings across the country, including at an event hosted by the Motion Picture Association in Washington, D.C.
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