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By NASA
Space changes you. It strengthens some muscles, weakens others, shifts fluids within your body, and realigns your sense of balance. NASA’s Human Research Program works to understand—and sometimes even counter—those changes so astronauts can thrive on future deep space missions.
NASA astronaut Loral O’Hara pedals on the Cycle Ergometer Vibration Isolation System (CEVIS) inside the International Space Station’s Destiny laboratory module.NASA Astronauts aboard the International Space Station work out roughly two hours a day to protect bone density, muscle strength and the cardiovascular system, but the longer they are in microgravity, the harder it can be for the brain and body to readapt to gravity’s pull. After months in orbit, returning astronauts often describe Earth as heavy, loud, and strangely still. Some reacclimate within days, while other astronauts take longer to fully recover.
Adjusting to Gravity
NASA’s SpaceX Crew-7 astronaut Jasmin Moghbeli after landing in the Gulf of America on March 12, 2024, completing 197 days in space.NASA/Joel Kowsky The crew of NASA’s SpaceX Crew-7 mission— NASA astronaut Jasmin Moghbeli, ESA (European Space Agency) astronaut Andreas Mogensen, JAXA (Japan Aerospace Exploration Agency) astronaut Satoshi Furukawa, and Roscosmos cosmonaut Konstantin Borisov—landed in March 2024 after nearly 200 days in space. One of the first tests volunteer crew members completed was walking with their eyes open and then closed.
“With eyes closed, it was almost impossible to walk in a straight line,” Mogensen said. In space, vision is the primary way astronauts orient themselves, but back on Earth, the brain must relearn how to use inner-ear balance signals. Moghbeli joked her first attempt at the exercise looked like “a nice tap dance.”
“I felt very wobbly for the first two days,” Moghbeli said. “My neck was very tired from holding up my head.” She added that, overall, her body readapted to gravity quickly.
Astronauts each recover on their own timetable and may encounter different challenges. Mogensen said his coordination took time to return. Furukawa noted that he could not look down without feeling nauseated. “Day by day, I recovered and got more stable,” he said.
NASA astronaut Loral O’Hara after landing in a remote area near the town of Zhezkazgan, Kazakhstan, on April 6, 2024.NASA/Bill Ingalls NASA astronaut Loral O’Hara returned in April 2024 after 204 days in space. She said she felt almost completely back to normal a week after returning to Earth. O’Hara added that her prior experience as an ocean engineer gave her insight into space missions. “Having those small teams in the field working with a team somewhere else back on shore with more resources is a good analog for the space station and all the missions we’re hoping to do in the future,” she said.
NASA astronaut Nichole Ayers, who flew her first space mission with NASA’s SpaceX Crew-10, noted that the brain quickly adapts to weightlessness by tuning out the vestibular system, which controls balance. “Then, within days of being back on Earth, it remembers again—it’s amazing how fast the body readjusts,” she said.
Expedition 69 NASA astronaut Frank Rubio outside the Soyuz MS-23 spacecraft after landing near the town of Zhezkazgan, Kazakhstan, on Sept. 27, 2023. NASA/Bill Ingalls When NASA astronaut Frank Rubio landed in Kazakhstan in September 2023, he had just completed a record 371-day mission—the longest single U.S. spaceflight.
Rubio said his body adjusted to gravity right away, though his feet and lower back were sore after more than a year without weight on them. Thanks to consistent workouts, Rubio said he felt mostly recovered within a couple of weeks.
Mentally, extending his mission from six months to a year was a challenge. “It was a mixed emotional roller coaster,” he said, but regular video calls with family kept him grounded. “It was almost overwhelming how much love and support we received.”
Crew-8 astronauts Matt Dominick, Jeanette Epps, Michael Barratt, and cosmonaut Alexander Grebenkin splashed down in October 2024 after 235 days on station. Dominick found sitting on hard surfaces uncomfortable at first. Epps felt the heaviness of Earth immediately. “You have to move and exercise every day, regardless of how exhausted you feel,” she said.
Barratt, veteran astronaut and board certified in internal and aerospace medicine, explained that recovery differs for each crew member, and that every return teaches NASA something new.
Still a Challenge, Even for Space Veterans
NASA astronaut Suni Williams is helped out of a SpaceX Dragon spacecraft aboard the SpaceX recovery ship after splashing down off the coast of Tallahassee, Florida, March 18, 2025. NASA/Keegan Barber Veteran NASA astronauts Suni Williams and Butch Wilmore returned from a nine-month mission with Crew-9 in early 2025. Despite her extensive spaceflight experience, Williams said re-adapting to gravity can still be tough. “The weight and heaviness of things is surprising,” she said. Like others, she pushed herself to move daily to regain strength and balance.
NASA astronaut Don Pettit arrives at Ellington Field in Houston on April 20, 2025, after returning to Earth aboard the Soyuz MS-25 spacecraft. NASA/Robert Markowitz NASA astronaut Don Pettit, also a veteran flyer, came home in April 2025 after 220 days on the space station. At 70 years old, he is NASA’s oldest active astronaut—but experience did not make gravity gentler. During landing, he says he was kept busy, “emptying the contents of my stomach onto the steppes of Kazakhstan.” Microgravity had eased the aches in his joints and muscles, but Earth’s pull brought them back all at once.
Pettit said his recovery felt similar to earlier missions. “I still feel like a little kid inside,” he said. The hardest part, he explained, isn’t regaining strength in big muscle groups, but retraining the small, often-overlooked muscles unused in space. “It’s a learning process to get used to gravity again.”
Recovery happens day by day—with help from exercise, support systems, and a little humor. No matter how long an astronaut is in space, every journey back to Earth is unique.
The Human Research Program help scientists understand how spaceflight environments affect astronaut health and performance and informs strategies to keep crews healthy for future missions to the Moon, Mars, and beyond. The program studies astronauts before, during, and after spaceflight to learn how the human body adapts to living and working in space. It also collects data through Earth-based analog missions that can help keep astronauts safer for future space exploration.
To learn more about how microgravity affects the human body and develop new ways to help astronauts stay healthy, for example, its scientists conduct bedrest studies – asking dozens of volunteers to spend 60 days in bed with their heads tilted down at a specific angle. Lying in this position tricks the body into responding as it would if the body was in space which allows scientists to trial interventions to hopefully counter some of microgravity’s effects. Such studies, through led by NASA, occur at the German Aerospace Center’s Cologne campus at a facility called :envihab – a combination of “environment” and “habitat.”
Additional Earth-based insights come from the Crew Health and Performance Exploration Analog (CHAPEA) and the Human Exploration Research Analog (HERA) at NASA’s Johnson Space Center in Houston. Both analogs recreate the remote conditions and scenarios of deep space exploration here on Earth with volunteer crews who agree to live and work in the isolation of ground-based habitats and endure challenges like delayed communication that simulates the type of interactions that will occur during deep space journeys to and from Mars. Findings from these ground-based missions and others will help NASA refine its future interventions, strategies, and protocols for astronauts in space.
NASA and its partners have supported humans continuously living and working in space since November 2000. After nearly 25 years of continuous human presence, the space station remains the sole space-based proving ground for training and research for deep space missions, enabling NASA’s Artemis campaign, lunar exploration, and future Mars missions.
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By NASA
Northrop Grumman’s Cygnus cargo craft awaits its capture by the International Space Station’s Canadarm2 robotic arm, commanded by NASA astronaut Matthew Dominick on Aug. 6, 2024.Credit: NASA NASA, Northrop Grumman, and SpaceX are targeting no earlier than 6:11 p.m. EDT, Sunday, Sept. 14, for the next launch to deliver science investigations, supplies, and equipment to the International Space Station. The mission is known as NASA’s Northrop Grumman Commercial Resupply Services 23, or Northrop Grumman CRS-23.
Watch the agency’s launch and arrival coverage on NASA+, Amazon Prime, and more. Learn how to watch NASA content through a variety of platforms, including social media.
Filled with more than 11,000 pounds of supplies, the Northrop Grumman Cygnus XL spacecraft, carried on a SpaceX Falcon 9 rocket, will launch from Space Launch Complex 40 at Cape Canaveral Space Force Station in Florida. This mission will be the first flight of the Cygnus XL, the larger, more cargo-capable version of the company’s solar-powered spacecraft.
Following arrival, astronauts aboard the space station will use the Canadarm2 to grapple Cygnus XL on Wednesday, Sept. 17, before robotically installing the spacecraft to the Unity module’s Earth-facing port for cargo unloading.
Highlights of space station research and technology demonstrations, facilitated by delivery aboard this Cygnus XL, include materials to produce semiconductor crystals in space and equipment to develop improvements for cryogenic fuel tanks. The spacecraft also will deliver a specialized UV light system to prevent the growth of microbe communities that form in water systems and supplies to produce pharmaceutical crystals that could treat cancer and other diseases.
Media interested in speaking to a science subject matter expert should contact Sandra Jones at: sandra.p.jones@nasa.gov. A copy of NASA’s media accreditation policy is available on the agency’s website.
The Cygnus XL spacecraft is scheduled to remain at the orbiting laboratory until March before it departs and burns up in the Earth’s atmosphere. Northrop Grumman has named the spacecraft the S.S. William “Willie” McCool, in honor of the NASA astronaut who perished in 2003 during the space shuttle Columbia accident.
NASA’s mission coverage is as follows (all times Eastern and subject to change based on real-time operations):
Wednesday, Sept. 10:
1 p.m. – International Space Station National Laboratory Science Webinar with the following participants:
Dr. Liz Warren, associate chief scientist, NASA’s International Space Station Program Research Office Phillip Irace, science program director, International Space Station National Laboratory Paul Westerhoff, regents professor, School of Sustainable Engineering and the Built Environment, Arizona State University Robert Garmise, director of formulation development; exploratory biopharmaceuticals, Bristol Myers Squibb Joel Sercel, founder and CEO, TransAstra Corporation and Mike Lewis, senior vice president, customer innovation, Voyager Technologies Mohammad Kassemi, research professor, Case Western University Media who wish to participate must register for Zoom access no later than one hour before the start of the webinar.
The webinar will be recorded and shared to the International Space Station National Lab’s YouTube channel following the event. Ask questions in advance using social accounts @ISS_CASIS and @Space_Station.
Friday, Sept 12
11:30 a.m. – Prelaunch media teleconference with the following participants:
Dina Contella, deputy manager, NASA’s International Space Station Program Dr. Liz Warren, associate chief scientist, NASA’s International Space Station Program Research Office Ryan Tintner, vice president, Civil Space Systems, Northrop Grumman Jared Metter, director, Flight Reliability, SpaceX Media who wish to participate by phone must request dial-in information by 5 p.m., Thursday, Sept. 11, by contacting the NASA Johnson newsroom at 281-483-5111 or jsccommu@mail.nasa.gov.
Audio of the teleconference will stream live on the agency’s website and YouTube.
Sunday, Sept. 14:
5:50 p.m. – Launch coverage begins on NASA+ and Amazon Prime
6:11 p.m. – Launch
Wednesday, Sept. 17:
5 a.m. – Arrival coverage begins on NASA+ and Amazon Prime
6:35 a.m. – Capture
8 a.m. – Installation coverage begins on NASA+ and Amazon Prime
NASA website launch coverage
Launch day coverage of the mission will be available on the NASA website. Coverage will include live streaming and blog updates beginning no earlier than 5:50 p.m. on Sept. 14, as the countdown milestones occur. On-demand streaming video on NASA+ and photos of the launch will be available shortly after liftoff. For questions about countdown coverage, contact the NASA Kennedy newsroom at 321-867-2468. Follow countdown coverage on our International Space Station blog for updates.
Attend Launch Virtually
Members of the public can register to attend this launch virtually. NASA’s virtual guest program for this mission also includes curated launch resources, notifications about related opportunities or changes, and a stamp for the NASA virtual guest passport following launch.
Watch, Engage on Social Media
Let people know you’re watching the mission on X, Facebook, and Instagram by following and tagging these accounts:
X: @NASA, @NASASpaceOps, @NASAKennedy, @Space_Station, @ISS_CASIS
Facebook: NASA, NASAKennedy, ISS, ISS National Lab
Instagram: @NASA, @NASAKennedy, @ISS, @ISSNationalLab
Coverage en Espanol
Did you know NASA has a Spanish section called NASA en Espanol? Check out NASA en Espanol on X, Instagram, Facebook, and YouTube for additional mission coverage.
Para obtener información sobre cobertura en español en el Centro Espacial Kennedy o si desea solicitar entrevistas en español, comuníquese con Antonia Jaramillo o Messod Bendayan a: antonia.jaramillobotero@nasa.gov o messod.c.bendayan@nasa.gov.
Learn more about the mission at:
https://www.nasa.gov/mission/nasas-northrop-grumman-crs-23/
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Josh Finch / Jimi Russell
Headquarters, Washington
202-358-1100
joshua.a.finch@nasa.gov / james.j.russell@nasa.gov
Steven Siceloff
Kennedy Space Center, Fla.
321-876-2468
steven.p.siceloff@nasa.gov
Sandra Jones / Joseph Zakrzewski
Johnson Space Center, Houston
281-483-5111
sandra.p.jones@nasa.gov / joseph.a.zakrzewski@nasa.gov
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Last Updated Sep 08, 2025 EditorLauren E. LowLocationNASA Headquarters Related Terms
Northrop Grumman Commercial Resupply Commercial Resupply International Space Station (ISS) ISS Research View the full article
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By NASA
NASA NASA astronauts Jonny Kim and Zena Cardman, both Expedition 73 Flight Engineers, pose for a portrait inside the International Space Station‘s Unity module during a break in weekend housecleaning and maintenance activities. Kim and Cardman are both part of NASA Astronaut Group 22 selected in June 2017 with 12 other astronauts, including two Canadian Space Agency astronauts, and affectionately nicknamed “The Turtles.”
In its third decade of continuous human presence, the space station has a far-reaching impact as a microgravity lab hosting technology, demonstrations, and scientific investigations from a range of fields. The research done by astronauts on the orbiting laboratory will inform long-duration missions like Artemis and future human expeditions to Mars.
Learn more about station activities by following the space station blog.
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By NASA
From left to right: JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui, and NASA astronauts Jonny Kim (seated), Zena Cardman, and Mike Fincke conduct training scenarios with their instructors at NASA’s Johnson Space Center in Houston, for their upcoming mission to the International Space Station. Credit: NASA/Helen Arase Vargas NASA astronaut Jonny Kim and JAXA (Japan Aerospace Exploration Agency) astronaut Kimiya Yui will connect with students in New York as they answer prerecorded science, technology, engineering, and mathematics (STEM) questions aboard the International Space Station.
The Earth-to-space call will begin at 9:20 a.m. EDT on Friday, Sept. 5, and will stream live on the agency’s Learn With NASA YouTube channel.
Media interested in covering the event must RSVP by 5 p.m. Wednesday, Sept. 3, to Sara Sloves at: 917-441-1234 or ssloves@thecomputerschool.org.
The Computer School will host this event in New York for middle school students. The goal of this event is to extend learning by exposing students to the real-world experiences and engineering challenges of astronauts working and living aboard the International Space Station.
For nearly 25 years, astronauts have continuously lived and worked aboard the space station, testing technologies, performing science, and developing skills needed to explore farther from Earth. Astronauts communicate with NASA’s Mission Control Center in Houston 24 hours a day through SCaN’s (Space Communications and Navigation) Near Space Network.
Research and technology investigations taking place aboard the space station benefit people on Earth and lay the groundwork for other agency deep space missions. As part of NASA’s Artemis campaign, the agency will send astronauts to the Moon to prepare for future human exploration of Mars, inspiring the world through discovery in a new Golden Age of innovation and exploration.
See more information on NASA in-flight calls at:
https://www.nasa.gov/stemonstation
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Gerelle Dodson
Headquarters, Washington
202-358-1600
gerelle.q.dodson@nasa.gov
Sandra Jones
Johnson Space Center, Houston
281-483-5111
sandra.p.jones@nasa.gov
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Last Updated Aug 28, 2025 LocationNASA Headquarters Related Terms
In-flight Education Downlinks Humans in Space International Space Station (ISS) Johnson Space Center Learning Resources NASA Headquarters View the full article
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