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El 2021 empata como el sexto año más cálido en la tendencia de calentamiento, según un análisis de la NASA
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By NASA
5 min read
Avatars for Astronaut Health to Fly on NASA’s Artemis II
An organ chip for conducting bone marrow experiments in space. Emulate NASA announced a trailblazing experiment that aims to take personalized medicine to new heights. The experiment is part of a strategic plan to gather valuable scientific data during the Artemis II mission, enabling NASA to “know before we go” back to the lunar surface and on to Mars.
The AVATAR (A Virtual Astronaut Tissue Analog Response) investigation will use organ-on-a-chip devices, or organ chips, to study the effects of deep space radiation and microgravity on human health. The chips will contain cells from Artemis II astronauts and fly side-by-side with crew on their approximately 10-day journey around the Moon. This research, combined with other studies on the health and performance of Artemis II astronauts, will give NASA insight into how to best protect astronauts as exploration expands to the surface of the Moon, Mars, and beyond.
AVATAR is NASA’s visionary tissue chip experiment that will revolutionize the very way we will do science, medicine, and human multi-planetary exploration.”
Nicky Fox
Associate Administrator, NASA Science Mission Directorate
“AVATAR is NASA’s visionary tissue chip experiment that will revolutionize the very way we will do science, medicine, and human multi-planetary exploration,” said Nicky Fox, associate administrator, Science Mission Directorate at NASA Headquarters in Washington. “Each tissue chip is a tiny sample uniquely created so that we can examine how the effects of deep space act on each human explorer before we go to ensure we pack the appropriate medical supplies tailored to each individual’s needs as we travel back to the Moon, and onward to Mars.”
The investigation is a collaboration between NASA, government agencies, and industry partners, leveraging commercial expertise to gain a deeper understanding of human biology and disease. This research could accelerate innovations in personalized healthcare, both for astronauts in space and patients on Earth.
Organ-on-a-chip: mimic for human health
Organ chips, also referred to as tissue chips or microphysiological systems, are roughly the size of a USB thumb drive and used to help understand — and then predict — how an individual might respond to a variety of stressors, such as radiation or medical treatments, including pharmaceuticals. Essentially, these small devices serve as “avatars” for human organs.
Organ chips contain living human cells that are grown to model the structures and functions of specific regions in human organs, such as the brain, lungs, heart, pancreas, and liver — they can beat like a heart, breathe like a lung, or metabolize like a liver. Tissue chips can be linked together to mimic how organs interact with each other, which is important for understanding how the whole human body responds to stressors or treatments.
Researchers and oncologists use human tissue chips today to understand how a specific patient’s cancer might react to different drugs or radiation treatments. To date, a standard milestone for organs-on-chips has been to keep human cells healthy for 30 days. However, NASA and other research institutions are pushing these boundaries by increasing the longevity of organ chips to a minimum of six months so that scientists can observe diseases and drug therapies over a longer period.
Bone marrow as bellwether
The Artemis II mission will use organ chips created using blood-forming stem and progenitor cells, which originate in the bone marrow, from Artemis II crew members.
Bone marrow is among the organs most sensitive to radiation exposure and, therefore, of central importance to human spaceflight. It also plays a vital role in the immune system, as it is the origin of all adult red and white blood cells, which is why researchers aim to understand how deep space radiation affects this organ.
Studies have shown that microgravity affects the development of bone marrow cells. Although the International Space Station operates in low Earth orbit, which is shielded from most cosmic and solar radiation by the Earth’s magnetosphere, astronauts often experience a loss of bone density. Given that Artemis II crew will be flying beyond this protective layer, AVATAR researchers also seek to understand how the combined stressors of deep space radiation and microgravity affect the developing cells.
To make the bone marrow organ chips, Artemis II astronauts will first donate platelets to a local healthcare system. The cells remaining from their samples will contain a small percentage of bone marrow-derived stem and progenitor cells. NASA-funded scientists at Emulate, Inc., which developed the organ chip technology used in AVATAR, will purify these cells with magnetic beads that bind specifically to them. The purified cells will then be placed in the bone marrow chips next to blood vessel cells and other supporting cells to model the structure and function of the bone marrow.
Investigating how radiation affects the bone marrow can provide insights into how radiation therapy and other DNA-damaging agents, such as chemotherapeutic drugs, impair blood cell formation. Its significance for both spaceflight and medicine on Earth makes the bone marrow an ideal organ to study in the Artemis II AVATAR project.
Passenger for research
“For NASA, organ chips could provide vital data for protecting astronaut health on deep space missions,” said Lisa Carnell, director of NASA’s Biological and Physical Sciences division at NASA Headquarters. “As we go farther and stay longer in space, crew will have only limited access to on-site clinical healthcare. Therefore, it’ll be critical to understand if there are unique and specific healthcare needs of each astronaut, so that we can send the right supplies with them on future missions.”
During the Artemis II mission, the organ chips will be secured in a custom payload developed by Space Tango and mounted inside the capsule during the mission. The battery-powered payload will maintain automated environmental control and media delivery to the organ chips throughout the flight.
For NASA, organ chips could provide vital data for protecting astronaut health on deep space missions.”
Lisa Carnell
Director of NASA’s Biological and Physical Sciences Division
Upon return, researchers at Emulate will examine how spaceflight affected the bone marrow chips by performing single-cell RNA sequencing, a powerful technique that measures how thousands of genes change within individual cells. The scientists will compare data from the flight samples to measurements of crew cells used in a ground-based immunology study happening simultaneously. This will provide the most detailed look at the impact of spaceflight and deep space radiation on developing blood cells to date.
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NASA’s Biological and Physical Sciences Division pioneers scientific discovery and enables exploration by using space environments to conduct investigations not possible on Earth. Studying biological and physical phenomenon under extreme conditions allows researchers to advance the fundamental scientific knowledge required to go farther and stay longer in space, while also benefitting life on Earth.
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By NASA
A SpaceX Falcon 9 rocket carrying Northrop Grumman’s Cygnus XL spacecraft is launched on NASA’s Northrop Grumman Commercial Resupply Services 23 mission to the International Space Station on Sunday, Sept. 14, 2025.Credit: NASA NASA is sending more science, technology demonstrations, and crew supplies to the International Space Station following the successful launch of the agency’s Northrop Grumman Commercial Resupply Services 23 mission, or Northrop Grumman CRS-23.
The company’s Cygnus XL spacecraft, carrying more than 11,000 pounds of cargo to the orbiting laboratory, lifted off at 6:11 p.m. EDT Sunday on a SpaceX Falcon 9 rocket from Space Launch Complex 40 at Cape Canaveral Space Force Station in Florida. This mission is the first flight of the larger, more cargo-capable version of the solar-powered spacecraft.
Cygnus XL is scheduled to be captured at 6:35 a.m. on Wednesday, Sept. 17, by the Canadarm2 robotic arm, which NASA astronaut Jonny Kim will operate with assistance from NASA astronaut Zena Cardman. Following capture, the spacecraft will be installed to the Unity module’s Earth-facing port for cargo unloading.
The resupply mission is carrying dozens of research experiments that will be conducted during Expedition 73, including materials to produce semiconductor crystals in space and equipment to develop improvements for cryogenic fuel tanks. The spacecraft also will deliver a specialized UV light system to prevent the growth of microbe communities that form in water systems and supplies to produce pharmaceutical crystals that could treat cancer and other diseases.
These are just a sample of the hundreds of scientific investigations conducted aboard the station in the areas of biology and biotechnology, Earth and space science, physical sciences, as well as technology development and demonstrations. For nearly 25 years, NASA has supported a continuous U.S. human presence aboard the orbiting laboratory, where astronauts have learned to live and work in space for extended periods of time. The space station is a springboard for developing a low Earth economy and NASA’s next great leaps in exploration, including Artemis missions to the Moon and American astronaut missions to Mars.
NASA’s arrival, capture, and installation coverage are as follows (all times Eastern and subject to change based on real-time operations):
Wednesday, Sept. 17
5 a.m. – Arrival coverage begins on NASA+, Amazon Prime, and more.
6:35 a.m. – Capture of Cygnus XL with the space station’s robotic arm.
8 a.m. – Installation coverage begins on NASA+, Amazon Prime, and more.
All coverage times are estimates and could be adjusted based on operations after launch. Follow the space station blog for the most up-to-date information.
Cygnus XL is scheduled to remain at the orbiting laboratory until March 2026, before it departs and disposes of several thousand pounds of trash through its re-entry into Earth’s atmosphere, where it will harmlessly burn up. The spacecraft is named the S.S. William “Willie” C. McCool, in honor of the NASA astronaut who perished in 2003 during the space shuttle Columbia accident.
Learn more about this NASA commercial resupply mission at:
https://www.nasa.gov/mission/nasas-northrop-grumman-crs-23/
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Josh Finch / Jimi Russell
Headquarters, Washington
202-358-1100
joshua.a.finch@nasa.gov / james.j.russell@nasa.gov
Steven Siceloff
Kennedy Space Center, Fla.
321-876-2468
steven.p.siceloff@nasa.gov
Sandra Jones / Joseph Zakrzewski
Johnson Space Center, Houston
281-483-5111
sandra.p.jones@nasa.gov / joseph.a.zakrzewski@nasa.gov
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Last Updated Sep 14, 2025 LocationNASA Headquarters Related Terms
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By NASA
4 Min Read NASA Uses Colorado Mountains for Simulated Artemis Moon Landing Course
NASA has certified a new lander flight training course using helicopters, marking a key milestone in crew training for Artemis missions to the Moon. Through Artemis, NASA explore the lunar South Pole, paving the way for human exploration farther into the solar system, including Mars.
The mountains in northern Colorado offer similar visual illusions and flight environments to the Moon. NASA partnered with the Colorado Army National Guard at the High-Altitude Army National Guard Aviation Training Site near Gypsum, Colorado, to develop the foundational flight training course.
“Artemis astronauts who will land on the Moon will need to master crew coordination and communication with one another,” said Paul Felker, acting deputy director of flight operations at NASA’s Johnson Space Center in Houston. “Much like they will on the Moon, astronaut teams are learning how to work together efficiently in a stressful environment to identify hazards, overcome degraded visual environments, and evaluate risks to successfully land.”
During the two-week certification run in late August, NASA astronauts Mark Vande Hei and Matthew Dominick participated in flight and landing training to help certify the course. The pair took turns flying a helicopter and navigating to landing zones. Artemis flight crew trainers, mission control leads, and lunar lander operational experts from NASA Johnson joined them on each helicopter flight to assess the instruction, training environment, and technical applications for crewed lunar missions.
NASA astronauts Matthew Dominick (left) and Mark Vande Hei (right) prepare to fly out to a landing zone in the Rocky Mountains as part of the certification run for the NASA Artemis course at the High-Altitude Army National Guard Aviation Training Site in Gypsum, Colorado, Aug. 26. NASA/Michael DeMocker A LUH-72 Lakota helicopter stirs up dust at the High-Altitude Army National Guard Aviation Training Site in Gypsum, Colorado, Aug. 28. NASA/Charles Beason A member of the Colorado Army National Guard peers out of a CH-47 Chinook in preparation for landing Aug. 22. NASA and trained instructors from the Army National Guard use a range of aircraft during flight training. Chinooks are used to demonstrate challenges with landing on the Moon. NASA/Charles Beason NASA astronauts Matthew Dominick (left) and Mark Vande Hei (right) celebrate after returning from a training flight Aug. 26 during a certification run for a lander flight training course for crewed Artemis missions. NASA/Michael DeMocker Paired with trained instructors with the Army National Guard, astronauts fly to mountaintops and valleys in a range of aircraft, including LUH-72 Lakotas, CH-47 Chinooks, and UH-60 Black Hawks. NASA/Charles Beason NASA astronaut Mark Vande Hei lands a helicopter as part of flight and landing training at the High Altitude Army National Guard Aviation Training Site Aug. 28. NASA/Michael DeMocker A member of the Colorado Army National Guard looks out of a CH-47 Chinook as it lands at a steep angle Aug. 29. A crater on the Moon could have a similar incline, posing landing challenges for future crewed Artemis missions. NASA/Michael DeMocker A LUH-72 Lakota helicopter flies over the mountains of northern Colorado Aug. 28 during a certification run for a lander flight training course for crewed Artemis missions. The mountains and valleys in Colorado have similar visual illusions to the Moon. NASA/Michael DeMocker The patch for the High-Altitude Army National Guard Aviation Training Site is pictured in the cupola of the International Space Station in 2023. NASA and the Colorado Army National Guard began working together in 2021 to develop a foundational lunar lander simulated flight training course for Artemis. NASA The NASA astronauts and trained instructor pilots with the Army National Guard flew to progressively more challenging landing zones throughout the course, navigating the mountainous terrain, and working together to quickly and efficiently land the aircraft.
Teams can train year-round using the course. Depending on the season, the snowy or dusty conditions can cause visual obstruction. Lunar dust can cause similar visual impairment during future crewed missions.
“Here in Colorado, we have specifically flown to dusty areas, so we know and understand just how important dust becomes during the final descent phase,” Vande Hei said. “Dust will interact with the lander thrusters on the Moon. During our flight training, we have had to revert to our instruments – just like we would on the Moon – because astronauts may lose all their visual cues when they’re near the surface.”
During Artemis III, four astronauts inside the agency’s Orion spacecraft on top of the SLS (Space Launch System rocket) will launch to meet SpaceX’s Starship Human Landing System in lunar orbit. Orion will then dock with the Starship system and two astronauts will board the lander. Astronauts will use the Starship lander to safely transport themselves from lunar orbit to the lunar surface. Following surface operations, the two astronauts will use Starship to launch from the lunar surface, back to lunar orbit, and dock with Orion to safely journey back to Earth.
The NASA-focused course has been in development since 2021. Vande Hei and Dominick are the 24th and 25th NASA astronauts to participate in and evaluate the course based on functionality and Artemis mission needs. One ESA (European Space Agency) astronaut has also participated in the course.
“This course will likely be one of the first group flight training opportunities for the Artemis III crew,” said NASA astronaut Doug Wheelock, who helped to develop the foundational training course for the agency. “While the astronauts will also participate in ground and simulation training in Ohio and Texas, the real-world flight environment in Colorado at offers astronauts an amazing simulation of the problem solving and decision making needed to control and maneuver a lunar lander across an equally dynamic landscape.”
Though the course is now certified for Artemis, teams will continue to evaluate the training based on astronaut and technical feedback to ensure mission success and crew safety.
Through the Artemis campaign, NASA will send astronauts to explore the Moon for scientific discovery, economic benefits, and to build the foundation for the first crewed missions to Mars for the benefit of all.
For more information about Artemis visit:
https://www.nasa.gov/artemis
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Last Updated Sep 10, 2025 EditorBeth RidgewayContactCorinne M. Beckingercorinne.m.beckinger@nasa.govLocationMarshall Space Flight Center Related Terms
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