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By NASA
NASA’s SpaceX 33rd commercial resupply mission successfully launched to deliver supplies and science investigations to the International Space Station from Space Launch Complex 40 at Cape Canaveral Space Force Station in Florida on Aug. 24, 2025.Credit: NASA Following a successful launch of NASA’s SpaceX 33rd commercial resupply mission, new scientific experiments and cargo for the agency are bound for the International Space Station.
The SpaceX Dragon spacecraft, carrying more than 5,000 pounds of supplies to the orbiting laboratory, lifted off at 2:45 a.m. EDT on Sunday, on the company’s Falcon 9 rocket from Space Launch Complex 40 at Cape Canaveral Space Force Station in Florida.
“Commercial resupply missions to the International Space Station deliver science that helps prove technologies for Artemis lunar missions and beyond,” said acting NASA Administrator Sean Duffy. “This flight will test 3D printing metal parts and bioprinting tissue in microgravity – technology that could give astronauts tools and medical support on future Moon and Mars missions.”
Live coverage of the spacecraft’s arrival will begin at 6 a.m., Monday, Aug. 25, on NASA+, Netflix, Amazon Prime, and more. Learn how to watch NASA content through a variety of platforms, including social media.
The spacecraft is scheduled to dock autonomously at approximately 7:30 a.m. to the forward port of the space station’s Harmony module.
In addition to food, supplies, and equipment for the crew, Dragon will deliver several experiments, including bone-forming stem cells for studying bone loss prevention and materials, to 3D print medical implants that could advance treatments for nerve damage on Earth. Dragon also will deliver bioprinted liver tissue to study blood vessel development in microgravity, as well as supplies to 3D print metal cubes in space.
These are just a sample of the hundreds of biology and biotechnology, physical sciences, Earth and space science investigations conducted aboard the orbiting laboratory. This research benefits people on Earth while laying the groundwork for other agency deep space missions. As part of NASA’s Artemis campaign, the agency will send astronauts to the Moon to prepare for future human exploration of Mars, inspiring the world through discovery in a new Golden Age of innovation and exploration.
During the mission, Dragon also will perform a reboost demonstration of station to maintain its current altitude. The hardware, located in the trunk of Dragon, contains an independent propellant system separate from the spacecraft to fuel two Draco engines using existing hardware and propellant system design. The boost kit will help sustain the orbiting lab’s altitude starting in September with a series of burns planned periodically throughout the fall of 2025. During NASA’s SpaceX 31st commercial resupply services mission on Nov. 8, 2024, the Dragon spacecraft performed its first demonstration of these capabilities.
The Dragon spacecraft is scheduled to remain at the space station until December, when it will depart the orbiting laboratory and return to Earth with research and cargo, splashing down off the coast of California.
Learn more about the International Space Station at:
https://www.nasa.gov/international-space-station
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Joshua Finch
Headquarters, Washington
202-358-1100
joshua.a.finch@nasa.gov
Steven Siceloff
Kennedy Space Center, Fla.
321-876-2468
steven.p.siceloff@nasa.gov
Sandra Jones / Joseph Zakrzewski
Johnson Space Center, Houston
281-483-5111
sandra.p.jones@nasa.gov / joseph.a.zakrzewski@nasa.gov
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Last Updated Aug 24, 2025 EditorJessica TaveauLocationNASA Headquarters Related Terms
Commercial Resupply International Space Station (ISS) ISS Research SpaceX Commercial Resupply View the full article
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By NASA
3 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
The Lunar Environment Structural Test Rig simulates the intense cold of the lunar night, ranging from 40 Kelvin (K) to 125 K while maintaining a vacuum environment. This creates a tool by which scientists and engineers can test materials, electronics, and flight hardware for future Moon and Mars missions, characterizing their behaviors at these temperatures while also validating their ability to meet design requirements.
Cryogenic engineer Adam Rice tests the Lunar Environment Structural Test Rig to simulate the thermal-vacuum conditions of the lunar night on Thursday, May 22, 2025.NASA/Jef Janis Facility Overview
The Lunar Environment Structural Test Rig (LESTR) approaches the problem of creating a simulated lunar environment by departing from typical fluid immersion or jacketed-and-chilled chamber systems. It does this by using a cryocooler to reject heat and bring the test section to any point desired by the test engineer, as low as 40 K or as high as 125 K in a vacuum environment. By combining high vacuum and cryogenic temperatures, LESTR enables safe, accurate, and cost-effective testing of materials and hardware destined for the Moon and beyond. Its modular setup supports a wide range of components — from spacesuits to rover wheels to electronics — while laying the foundation for future Moon and Mars mission technologies.
Quick Facts
LESTR is a cryogenic mechanical test system built up within a conventional load frame with the goal of providing a tool to simulate the thermal-vacuum conditions of the lunar night to engineers tasked with creating the materials, tools, and machinery to succeed in NASA’s missions.
LESTR replicates extreme lunar night environments — including temperatures as low as 40 K and high vacuum (<5×10⁻⁷ Torr) — enabling true-to-space testing without liquid cryogens. Unlike traditional “wet” methods, LESTR uses a cryocooler and vacuum system to create an environment accurate to the lunar surface. From rover wheels to spacesuits to electronics, LESTR supports static and dynamic testing across a wide range of Moon and Mars mission hardware. With scalable architecture and precision thermal control, LESTR lays critical groundwork for advancing the technologies of NASA’s Artemis missions and beyond. Capabilities
Specifications
Temperature Range: 40 K to 125 K Load Capacity: ~10 kN Vacuum Level: <5×10⁻⁷ Torr Test Volume (Cold Box Dimensions): 7.5 by 9.5 by 11.5 inches Maximum Cycle Rate: 100 Hz Time to Vacuum:10⁻⁵ Torr in less than one hour 10⁻⁶ Torr in four hours Features
Dry cryogenic testing (no fluid cryogen immersion) “Dial-a-temperature” control for precise thermal conditions Integrated optical extensometer for strain imaging Digital image correlation and electrical feedthroughs support a variety of data collection methods Native support for high-duration cyclic testing Applications
Cryogenic Lifecycle Testing: fatigue, fracture, and durability assessments Low-Frequency Vibration Testing: electronics qualification for mobility systems Static Load Testing: material behavior characterization in lunar-like environments Suspension and Drivetrain Testing: shock absorbers, wheels, springs, and textiles Textiles Testing: evaluation of spacesuits and habitat fabrics Dynamic Load Testing: up to 10 kN linear capacity, 60 mm stroke Contact
Cryogenic and Mechanical Evaluation Lab Manager: Andrew Ring
216-433-9623
Andrew.J.Ring@nasa.gov
LESTR Technical Lead: Ariel Dimston
216-433-2893
Ariel.E.Dimston@nasa.gov
Using Our Facilities
NASA’s Glenn Research Center in Cleveland provides ground test facilities to industry, government, and academia. If you are considering testing in one of our facilities or would like further information about a specific facility or capability, please let us know.
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The Lunar Environment Structural Test Rig simulates the intense cold of the lunar night on Friday, June 6, 2025.NASA/Steven Logan The Lunar Environment Structural Test Rig uses a cryocooler to reject heat and bring the test section as low as 40 Kelvin in a vacuum environment on Thursday, May 22, 2025.NASA/Jef Janis Keep Exploring Discover More Topics From NASA
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By NASA
NASA’s SpaceX 33rd commercial resupply mission will launch on the company’s Dragon spacecraft on the SpaceX Falcon 9 rocket to deliver research and supplies to the International Space StationNASA NASA and SpaceX are targeting no earlier than 2:45 a.m. EDT on Sunday, Aug. 24, for the next launch to deliver scientific investigations, supplies, and equipment to the International Space Station.
Filled with more than 5,000 pounds of supplies, the SpaceX Dragon spacecraft, on the company’s Falcon 9 rocket, will lift off from Launch Complex 40 at Cape Canaveral Space Force Station in Florida. Dragon will dock autonomously about 7:30 a.m. on Monday, Aug. 25, to the forward port of the space station’s Harmony module.
NASA’s SpaceX 33rd commercial resupply mission will launch from Launch Complex 40 at Cape Canaveral Space Force Station in Florida.NASA This launch is the 33rd SpaceX commercial resupply services mission to the orbital laboratory for the agency, and the 13th SpaceX launch under the Commercial Resupply Services-2 contract. The first 20 launches were under the original resupply services contract.
Watch agency launch and arrival coverage on NASA+, Netflix, Amazon Prime, and more. Learn how to watch NASA content through a variety of platforms, including social media.
NASA’s live launch coverage will begin at 2:25 a.m. on Aug 24. Dragon’s arrival coverage will begin at 6 a.m. on Aug. 25. For nearly 25 years, the International Space Station has provided research capabilities used by scientists from over 110 countries to conduct more than 4,000 groundbreaking experiments in microgravity. Research conducted aboard the space station advances Artemis missions to the Moon and human exploration of Mars, while providing multiple benefits to humanity.
Arrival & Departure
The SpaceX Dragon spacecraft will arrive at the space station and dock autonomously to the forward port of the station’s Harmony module at approximately 7:30 a.m. on Monday, Aug. 25. NASA astronauts Mike Fincke and Jonny Kim will monitor the spacecraft’s arrival. It will stay docked to the orbiting laboratory for about four months before splashing down and returning critical science and hardware to teams on Earth.
NASA astronauts Mike Fincke and Jonny Kim will monitor the arrival of the SpaceX Dragon cargo spacecraft from the International Space Station.NASA Research Highlights
Preventing bone loss in space
Microgravity Associated Bone Loss-B (MABL-B) assesses the effects of microgravity on bone marrow stem cells and may provide a better understanding of the basic molecular mechanisms of bone loss that occurs during spaceflight and from normal aging on Earth.NASA A study of bone-forming stem cells in microgravity could provide insight into the basic mechanisms of the bone loss astronauts experience during long-duration space flight ahead of future exploration of the Moon and Mars.
Researchers identified a protein in the body called IL-6 that can send signals to stem cells to promote either bone formation or bone loss. This work evaluates whether blocking IL-6 signals could reduce bone loss during spaceflight. Results could improve our understanding of bone loss on Earth due to aging or disease and lead to new prevention and treatment strategies.
Printing parts, tools in space
Printing parts, tools in space
The objective of the Metal 3D printer aboard the International Space Station is to gain experience with operating and evaluating the manufacturing of spare parts in microgravity to support long duration space missions.NASA As mission duration and distance from Earth increase, resupply becomes harder. Additive manufacturing, or 3D printing, could be used to make parts and dedicated tools on demand, enhancing mission autonomy.
Research aboard the space station has made strides in 3D printing with plastic, but it is not suitable for all uses. Investigations from ESA’s (European Space Agency) Metal 3D Printer builds on recent successful printing of the first metal parts in space.
Bioprinting tissue in microgravity
Maturation of Vascularized Liver Tissue Construct in Zero Gravity (MVP Cell-07) is a biotechnology experiment studying bioprinted, or lab grown, liver tissues complete with blood vessels in space. The results could improve astronaut health on long missions and lead to new ways to treat patients on Earth.NASA Researchers plan to bioprint liver tissue containing blood vessels on the ground and examine how the tissue develops in microgravity. Results could help support the eventual production of entire functional organs for transplantation on Earth.
A previous mission tested whether this bioprinted liver tissue survived and functioned in space. This experimental round could show whether microgravity improves the development of the bioprinted tissue.
Biomanufacturing drug-delivery medical devices
The InSPA-Auxilium Bioprinter will test 3D printing medical implant devices designed to deliver drugs and treat various health conditions such as nerve inuries. Printing on the International Space Station may produce higher-quality devices than on Earth.NASA Scientists are creating an implantable device in microgravity that could support nerve regrowth after injuries. The device is created through bioprinting, a type of 3D printing that uses living cells or proteins as raw materials.
Traumatic injuries can create gaps between nerves, and existing treatments have a limited ability to restore nerve function and may result in impaired physical function. A bioprinted device to bridge nerve gaps could accelerate recovery and preserve function.
Cargo Highlights
NASA’s SpaceX 33rd commercial resupply mission will carry over 5,000 pounds of cargo to the International Space Station.NASA Hardware
Launch:
Reboost Kit – This kit will perform a reboost demonstration of the station to maintain its current altitude. The hardware, located in Dragon’s trunk, contains an independent propellant system, separate from the spacecraft’s main system, to fuel two Draco engines using existing hardware and propellant system design. The boost kit will demonstrate the capability to maintain the orbiting lab’s altitude starting in September with a series of burns planned periodically throughout the fall of 2025. During NASA’s SpaceX 31st commercial resupply services mission, the Dragon spacecraft first demonstrated these capabilities on Nov. 8, 2024. Poly Exercise Rope Kit – These exercise ropes distribute the desired exercise loads through a series of pulleys for the Advanced Restrictive Exercise Device. The ropes have a limited life cycle, and it will be necessary to replace them once they have reached their limit. Brine Filter – These filters remove solid particles from liquid in urine during processing as a part of the station’s water recovery system. Acoustic Monitor – A monitor that measures sound and records the data for download. This monitor will replace the sound level meter and the acoustic dosimeter currently aboard the orbiting laboratory. Multi-filtration Bed – This space unit will support the Water Processor Assembly and continue the International Space Station Program’s effort to replace a fleet of degraded units aboard the station to improve water quality through a single bed. Water Separator Orbital Unit – The unit draws air and condensate mixture from a condensing heat exchanger and separates the two components. The air is returned to the cabin air assembly outlet air-flow stream, and the water is delivered to the condensate bus. This unit launches to maintain in-orbit sparing while another is being returned for repair. Anomaly Gas Analyzer Top Assembly – This battery-powered device detects and monitors gases aboard the station, including oxygen, carbon dioxide, hydrogen chloride, hydrogen fluoride, ammonia, carbon monoxide, and hydrogen cyanide. It also measures cabin pressure, humidity, and temperature. It replaces the Compound Specific Analyzer Combustion Products as the primary tool for detecting airborne chemicals and conditions. Separator Pump (Water Recovery and Management) – This electrically-powered pump separates liquids and gases while rotating. It includes a scoop pump that moves the separated liquid into storage containers for use in other systems. The pump also contains sensor components and a filter to reduce electrical interference from the motor. Launching to maintain in-orbit sparing. Reducer Cylinder Assembly & Emergency Portable Breathing Apparatus – Together, this hardware provides 15 minutes of oxygen to a crew member in case of an emergency (smoke, fire, alarm). Two are launching to maintain a minimum in-orbit spare requirement. Passive Separator Flight Experiment – This experiment will test a new method for separating urine and air using existing technology that combines a water-repellent urine hose with an airflow separator from the station’s existing Waste Hygiene Compartment. Improved Resupply Water Tanks – Two tanks, each holding approximately 160 pounds of potable water, to supplement the Urine Processing Assembly. NORS (Nitrogen/Oxygen Recharge System) Maintenance Tank/Recharge Tank Assembly, Nitrogen – The NORS maintenance kit comprises two assemblies: the NORS recharge tank assembly and the NORS vehicle interface assembly. The recharge tank assembly will be pressurized with nitrogen gas for launch. The vehicle interface assembly will protect the recharge tank assembly for launch and stowage aboard the space station. Launching to maintain reserve oxygen levels on station. Swab Kits – These quick-disconnect cleaning kits are designed and created to replace in-orbit inventory. Return:
Oxygen Generation Assembly Pump – The assembly pump converts potable water from the water recovery system into oxygen and hydrogen. The oxygen is sent to the crew cabin, and the hydrogen is either vented or used to produce more water. The International Space Station has been using this process to produce oxygen and hydrogen for 15 years, and this unit will be retired upon its return to Earth. The flight support equipment within will be refurbished and used in a new pump launched aboard a future flight. Carbon Dioxide Monitoring Assembly – A carbon dioxide monitor that measures the gas using the infrared absorption sensor. It expired in July 2025 and will return for refurbishment. Meteoroid Debris Cover Center Section Assembly – This external multilayer insulation provides thermal and micro-meteoroid orbital debris protection on the node port. After it is removed and replaced with a new assembly launching on NASA’s Northrop Grumman 23rd commercial resupply services mission, this unit will return for repair or used for spare parts. Multi-filtration Bed – This spare unit supports the Water Processor Assembly, which improves water quality aboard the International Space Station. Its return is part of an ongoing effort to replace a degraded fleet of in-orbit units. After its use, this multi-filtration bed will be refurbished for future re-flight. Separator Pump – This electrically powered pump separates liquids and gases while rotating. It includes a scoop pump that moves the separated liquid into storage containers for use in other systems. The pump also contains sensor components and a filter to reduce electrical interference from the motor. This unit is designed to run to failure, and after investigation and testing, it will be returned for repair and future flight. Rate Gyro Enclosure Assembly – The Rate Gyro Assembly determines the space station’s rate of angular motion. It is returning for repair and refurbishment and will be used as a spare. NORS (Nitrogen/Oxygen Recharge System) Maintenance Kit (Oxygen) – The NORS Maintenance Kit comprises two assemblies: the NORS Recharge Tank Assembly and the NORS Vehicle Interface Assembly. The recharge tank assembly will be pressurized with Nitrogen gas for launch. The vehicle interface assembly will protect the recharge tank assembly for launch and stowage aboard the space station. They are routinely returned for reuse and re-flight. The kit also includes a VIA bag (vehicle interface assembly) with foam, which is used as a cargo transfer bag for launch and return to protect the tank. Watch, Engage
Watch agency launch and arrival coverage on NASA+, Netflix, Amazon Prime, and more. Learn how to watch NASA content through a variety of platforms, including social media.
NASA’s live launch coverage will begin at 2:25 a.m. on Aug 24. Dragon’s arrival coverage will begin at 6 a.m. on Aug. 25.
Read more about how to watch and engage.
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