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By NASA
Artemis II NASA astronauts (left to right) Reid Wiseman, Victor Glover, and Christina Koch, and CSA (Canadian Space Agency) astronaut Jeremy Hansen stand in the white room on the crew access arm of the mobile launcher at Launch Pad 39B as part of an integrated ground systems test at Kennedy Space Center in Florida on Wednesday, Sept. 20, 2023. The test ensures the ground systems team is ready to support the crew timeline on launch day.NASA/Frank Michaux With Artemis II, NASA is taking the science of living and working in space beyond low Earth orbit. While the test flight will help confirm the systems and hardware needed for human deep space exploration, the crew also will be serving as both scientists and volunteer research subjects, completing a suite of experiments that will allow NASA to better understand how human health may change in deep space environments. Results will help the agency build future interventions, protocols, and preventative measures to best protect astronauts on future missions to the lunar surface and to Mars.
Science on Artemis II will include seven main research areas:
ARCHeR: Artemis Research for Crew Health and Readiness
NASA’s Artemis II mission provides an opportunity to explore how deep space travel affects sleep, stress, cognition, and teamwork — key factors in astronaut health and performance. While these effects are well-documented in low Earth orbit, they’ve never been fully studied during lunar missions.
Artemis II astronauts will wear wristband devices that continuously monitor movement and sleep patterns throughout the mission. The data will be used for real-time health monitoring and safety assessments, while pre- and post-flight evaluations will provide deeper insights into cognition, behavior, sleep quality, and teamwork in the unique environment of deep space and the Orion spacecraft.
The findings from the test flight will inform future mission planning and crew support systems, helping NASA optimize human performance for the next era of exploration on the Moon and Mars.
Immune Biomarkers
Saliva provides a unique window into how the human immune system functions in a deep space environment. Tracing changes in astronauts’ saliva from before, during, and after the mission will enable researchers to investigate how the human body responds to deep space in unprecedented ways.
Dry saliva will be collected before, during, and after the mission. It will be blotted onto specialized paper in pocket-sized booklets since equipment needed to preserve wet spit samples in space – including refrigeration – will not be available due to volume constraints. To augment that information, liquid saliva and blood samples will be collected before and after the mission.
NASA Astronaut Randy Bresnik prepares to collect a dry saliva sample aboard the International Space Station. The process, which helps scientists investigate how the immune system is affected by spaceflight and will be part of the Artemis II mission, involves blotting saliva onto special paper that’s stored in pocket-sized booklets.Credit: NASA With these wet and dry saliva samples, scientists will gain insights into how the astronauts’ immune systems are affected by the increased stresses of radiation, isolation, and distance from Earth during their deep space flight. They also will examine whether otherwise dormant viruses are reactivated in space, as has been seen previously on the International Space Station with viruses that can cause chickenpox and shingles.
The information gathered from this study, when combined with data from other missions, will help researchers develop ways to keep crew members safe and healthy as we explore farther and travel for longer periods on deep space missions.
AVATAR: A Virtual Astronaut Tissue Analog Response
AVATAR is another important component of NASA’s strategy to gain a holistic understanding of how the deep space environment affects humans. Scientists plan to use organ-on-a-chip technology during Artemis II, marking the first time these devices will be used beyond the Van Allen belts.
Roughly the size of a USB thumb drive, the chips will measure how individual astronauts respond to deep space stressors, including extreme radiation and microgravity. The organ chips will contain cells developed from preflight blood donations provided by crew members to create miniature stand-ins, or “avatars,” of their bone marrow. Bone marrow plays a vital role in the immune system and is particularly sensitive to radiation, which is why scientists selected it for this study.
An organ chip for conducting bone marrow experiments in space. Credit: Emulate
A key goal for this research is to validate whether organ chips can serve as accurate tools for measuring and predicting human responses to stressors. To evaluate this, scientists will compare AVATAR data with space station findings, as well as with samples taken from the crew before and after flight.
AVATAR could inform measures to ensure crew health on future deep space missions, including personalizing medical kits to each astronaut. For citizens on Earth, it could lead to advancements in individualized treatments for diseases such as cancer.
AVATAR is a demonstration of the power of public-private partnerships. It’s a collaboration between government agencies and commercial space companies: NASA, National Center for Advancing Translational Sciences within the National Institutes of Health, Biomedical Advanced Research and Development Authority, Space Tango, and Emulate.
Artemis II Standard Measures
The crew also will become the first astronauts in deep space to participate in the Spaceflight Standard Measures study, an investigation that’s been collecting data from participating crew members aboard the space station and elsewhere since 2018. The study aims to collect a comprehensive snapshot of astronauts’ bodies and minds by gathering a consistent set of core measurements of physiological response.
The crew will provide biological samples including blood, urine, and saliva for evaluating nutritional status, cardiovascular health, and immunological function starting about six months before their launch. The crew also will participate in tests and surveys evaluating balance, vestibular function, muscle performance, changes in their microbiome, as well as ocular and brain health. While in space, data gathering will include an assessment of motion sickness symptoms. After landing, there will be additional tests of head, eye, and body movements, among other functional performance tasks. Data collection will continue for a month after their return.
All this information will be available for scientists interested in studying the effects of spaceflight via request to NASA’s Life Sciences Data Archive. The results from this work could lead to future interventions, technologies, and studies that help predict the adaptability of crews on a Mars mission.
Radiation Sensors Inside Orion
During the uncrewed Artemis I mission, Orion was blanketed in 5,600 passive and 34 active radiation sensors. The information they gathered assured researchers Orion’s design can provide protection for crew members from hazardous radiation levels during lunar missions. That doesn’t mean that scientists don’t want more information, however.
Similar to Artemis I, six active radiation sensors, collectively called the Hybrid Electronic Radiation Assessors, will be deployed at various locations inside the Orion crew module. Crew also will wear dosimeters in their pockets. These sensors will provide warnings of hazardous radiation levels caused by space weather events made by the Sun. If necessary, this data will be used by mission control to drive decisions for the crew to build a shelter to protect from radiation exposure due to space weather.
Additionally, NASA has again partnered the German Space Agency DLR for an updated model of their M-42 sensor – an M-42 EXT – for Artemis II. The new version offers six times more resolution to distinguish between different types of energy, compared to the Artemis I version. This will allow it to accurately measure the radiation exposure from heavy ions which are thought to be particularly hazardous for radiation risk. Artemis II will carry four of the monitors, affixed at points around the cabin by the crew.
Collectively, sensor data will paint a full picture of radiation exposures inside Orion and provide context for interpreting the results of the ARCHeR, AVATAR, Artemis II Standard Measures, and Immune Biomarkers experiments.
Lunar Observations Campaign
The Artemis II crew will take advantage of their location to explore the Moon from above. As the first humans to see the lunar surface up close since 1972, they’ll document their observations through photographs and audio recordings to inform scientists’ understanding of the Moon and share their experience of being far from Earth. It’s possible the crew could be the first humans to see certain areas of the Moon’s far side, though this will depend on the time and date of launch, which will affect which areas of the Moon will be illuminated and therefore visible when the spacecraft flies by.
Spacecraft such as NASA’s Lunar Reconnaissance Orbiter have been surveying and mapping the Moon for decades, but Artemis II provides a unique opportunity for humans to evaluate the lunar surface from above. Human eyes and brains are highly sensitive to subtle changes in color, texture, and other surface characteristics. Having the crew observe the lunar surface directly – equipped with questions that scientists didn’t even know to ask during Apollo missions – could form the basis for future scientific investigations into the Moon’s geological history, the lunar environment, or new impact sites.
This visualization simulates what the crew of Artemis II might see out the Orion windows on the day of their closest approach to the Moon. It compresses 36 hours into a little more than a minute as it flies the virtual camera on a realistic trajectory that swings the spacecraft around the Moon’s far side. This sample trajectory is timed so that the far side is fully illuminated when the astronauts fly by, but other lighting conditions are possible depending on the exact Artemis II launch date. The launch is scheduled for no later than April of 2026. NASA Goddard/Ernie Wright
It will also offer the first opportunity for an Artemis mission to integrate science flight control operations. From their console in the flight control room in mission control, a science officer will consult with a team of scientists with expertise in impact cratering, volcanism, tectonism, and lunar ice, to provide real-time data analysis and guidance to the Artemis II crew in space. During the mission, the lunar science team will be located in mission control’s Science Evaluation Room at NASA’s Johnson Space Center in Houston.
Lessons learned during Artemis II will pave the way for lunar science operations on future missions.
CubeSats
Several additional experiments are hitching a ride to space onboard Artemis II in the form of CubeSats – shoe-box-sized technology demonstrations and scientific experiments. Though separate from the objectives of the Artemis II mission, they may enhance understanding of the space environment.
Technicians install the Korea AeroSpace Administration (KASA) K-Rad Cube within the Orion stage adapter inside the Multi-Payload Processing Facility at NASA’s Kennedy Space Center in Florida on Tuesday, Sept. 2, 2025. The K-Rad Cube, about the size of a shoebox, is one of the CubeSats slated to fly on NASA’s Artemis II test flight in 2026. Credit: NASA Four international space agencies have signed agreements to send CubeSats into space aboard the SLS (Space Launch System) rocket, each with their own objectives. All will be released from an adapter on the SLS upper stage into a high-Earth orbit, where they will conduct an orbital maneuver to reach their desired orbit.
ATENEA – Argentina’s Comisión Nacional de Actividades Espaciales will collect data on radiation doses across various shielding methods, measure the radiation spectrum around Earth, collect GPS data to help optimize future mission design, and validate a long-range communications link.
K-Rad Cube – The Korea Aerospace Administration will use a dosimeter made of material designed to mimic human tissue to measure space radiation and assess biological effects at various altitudes across the Van Allen radiation belt.
Space Weather CubeSat – The Saudi Space Agency will measure aspects of space weather, including radiation, solar X-rays, solar energetic particles, and magnetic fields, at a range of distances from Earth.
TACHELES – The Germany Space Agency DLR will collect measurements on the effects of the space environment on electrical components to inform technologies for lunar vehicles.
Together, these research areas will inform plans for future missions within NASA’s Artemis campaign. Through Artemis, NASA will send astronauts to explore the Moon for scientific discovery, economic benefits, and build the foundation for the first crewed missions to Mars.
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By NASA
NASA/Keegan Barber The members of NASA’s SpaceX Crew-10 mission – Roscosmos cosmonaut Kirill Peskov, left, NASA astronauts Nichole Ayers and Anne McClain, and JAXA (Japan Aerospace Exploration Agency) astronaut Takuya Onishi – are all smiles after having landed in the Pacific Ocean off the coast of San Diego, Calif., Saturday, Aug. 9, 2025. The crew spent seven months aboard the International Space Station.
Along the way, Crew-10 contributed hundreds of hours to scientific research, maintenance activities, and technology demonstrations. McClain, Ayers, and Onishi completed investigations on plant and microalgae growth, examined how space radiation affects DNA sequences in plants, observed how microgravity changes human eye structure and cells in the body, and more. The research conducted aboard the orbiting laboratory advances scientific knowledge and demonstrates new technologies that enable us to prepare for human exploration of the Moon and Mars.
McClain and Ayers also completed a spacewalk on May 1. It was the third spacewalk for McClain and the first for Ayers.
See more photos from Crew-10 Splashdown.
Image credit: NASA/Keegan Barber
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By European Space Agency
Image: Webb takes a fresh look at a classic deep field View the full article
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By NASA
Curiosity Navigation Curiosity Home Mission Overview Where is Curiosity? Mission Updates Science Overview Instruments Highlights Exploration Goals News and Features Multimedia Curiosity Raw Images Images Videos Audio Mosaics More Resources Mars Missions Mars Sample Return Mars Perseverance Rover Mars Curiosity Rover MAVEN Mars Reconnaissance Orbiter Mars Odyssey More Mars Missions Mars Home 3 min read
Curiosity Blog, Sols 4607-4608: Deep Dip
NASA’s Mars rover Curiosity acquired this image, looking toward the upper slopes of Mount Sharp, using its Left Navigation Camera (Left Navcam) on July 20, 2025. Curiosity captured the image on Sol 4605, or Martian day 4,605 of the Mars Science Laboratory mission, at 18:58:26 UTC. NASA/JPL-Caltech Written by Deborah Padgett, MSL OPGS Task Lead at NASA’s Jet Propulsion Laboratory
Earth planning date: Monday, July 21, 2025
Curiosity continues our exploration of the fractured boxwork terrain on the slopes of Mount Sharp. After a successful 5-meter drive (about 16 feet), our rover is resting in a hollow on its way to a boxwork ridge viewpoint. Over the weekend, Curiosity began an atmospheric observation with the SAM instrument, which will continue into today’s plan. Because the SAM instrument is complex and powerful, it uses a great deal of energy when it operates, causing what we call a “deep dip” in the battery charge level. This means that we have to wait a bit after the SAM observations complete for the battery to recharge enough for Curiosity to observe its surroundings with other science instruments, or move its arm or wheels. For this reason, the plan today does not include a drive, and contact science at this location will be done on the second sol of the plan.
On Sol 4607, Curiosity will begin the day with SAM atmospheric composition activity, which will run for several hours. After it finishes, we will use the rover’s navigation camera to perform a cloud altitude observation, looking for cloud shadows on the upper reaches of Mount Sharp, and clouds drifting by overhead at the zenith. Overnight, Curiosity’s battery will recharge, allowing us to perform a targeted science block on the morning of Sol 4608. This starts with Navcam observations of dust opacity across the floor of Gale Crater, then a measurement of dust in the air toward the Sun with Mastcam. Curiosity then turns Mastcam toward the ridge ahead to obtain a 15×1 mosaic on target “Cueva De Los Vencejos Y Murcielagos (Cave of Swifts and Bats).” Afterwards, Mastcam will look back along Curiosity’s tracks, hoping to see freshly broken rocks and determine the texture of disturbed ground. Next, ChemCam’s laser spectrograph will zap a nodular rock pillar named for the famous high-altitude “Lake Titicaca” bordering Bolivia and Peru. A second ChemCam observation with the RMI telescopic camera will study stratigraphy on the Mishe Mokwa butte with a 5×2 image mosaic. Mastcam will finish off this science block by looking at the pits left behind by the ChemCam laser on target “Lake Titicaca.”
In the afternoon, Curiosity’s arm will reach out to brush the dust from the bedrock target “La Tranquita,” then observe it with the MAHLI microscopic imager and APXS. MAHLI and APXS will also investigate plate-like rock formations at target “Aqua Dulce.” A third target with more complex rock structures dubbed “Paposo,” after a natural monument along the Pacific Coast of northern Chile, will be imaged only by MAHLI. The next morning will include another targeted science block. Curiosity will then drive away toward the next viewpoint in the boxwork terrain of Mars.
For more Curiosity blog posts, visit MSL Mission Updates
Learn more about Curiosity’s science instruments
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Curiosity Navigation Curiosity Home Mission Overview Where is Curiosity? Mission Updates Science Overview Instruments Highlights Exploration Goals News and Features Multimedia Curiosity Raw Images Images Videos Audio Mosaics More Resources Mars Missions Mars Sample Return Mars Perseverance Rover Mars Curiosity Rover MAVEN Mars Reconnaissance Orbiter Mars Odyssey More Mars Missions Mars Home NASA’s Mars rover Curiosity acquired this image, looking south across the large boxwork structures, using its Left Navigation Camera on July 17, 2025. A series of ridges and hollows forms the dramatic topography in the foreground, while the distant buttes expose additional sedimentary structures. Curiosity acquired this image on Sol 4602, or Martian day 4,602 of the Mars Science Laboratory mission, at 17:49:18 UTC. NASA/JPL-Caltech Written by Lauren Edgar, Planetary Geologist at USGS Astrogeology Science Center
Earth planning date: Friday, July 18, 2025
Curiosity has started to investigate the main exposure of the boxwork structures! What was once a distant target is now on our doorstep, and Curiosity is beginning to explore the ridges and hollows that make up this terrain, to better understand their chemistry, morphology, and sedimentary structures.
I was on shift as Long Term Planner during this three-sol weekend plan, and the team put together a very full set of activities to thoroughly investigate this site — from the sky to the sand. The plan starts with Navcam and Mastcam observations to assess the amount of dust in the atmosphere, followed by a large Mastcam mosaic to characterize the resistant ridge on which the rover is parked. ChemCam will also acquire a LIBS observation on a target named “Vicuna” to assess the chemistry of a well-exposed vein. The team chose this parking location to characterize the chemistry and textures of this topographic ridge (to compare with topographic lows), so the next part of the plan involves contact science using APXS and MAHLI to look at different parts of the nodular bedrock in our workspace, at targets named “Totoral” and “Sillar.” There’s also a MAHLI observation of the same vein that ChemCam targeted.
The second sol involves more Mastcam imaging to look at different parts of this prominent ridge, along with a ChemCam LIBS observation on top of the ridge, and a ChemCam RMI mosaic to document the sedimentary structures in a distant boxwork feature. Navcam will also be used to look for dust devils. Then Curiosity will take a short drive of about 5 meters (about 16 feet) to explore the adjacent hollow (seen as the low point in the foreground of the above Navcam image). After the drive we’ll take more images for context, and to prepare for targeting in Monday’s plan.
After all of this work it’s time to pause and take a deep breath… of Martian atmosphere. The weekend plan involves an exciting campaign to look for variations in atmospheric chemistry between night and day. So Curiosity will take an overnight APXS atmospheric observation at the same time that two instruments within SAM assess its chemical and isotopic abundance.
On the third sol Curiosity will acquire a ChemCam passive sky observation, leading to a great set of atmospheric data. These measurements will be compared to even more atmospheric activities in Monday’s plan to get the full picture. As you can imagine, this plan requires a lot of power, but it’s worth it for all of the exciting science that we can accomplish here.
The road ahead has many highs and lows (literally), but I can’t wait to see what Curiosity will accomplish. The distant buttes remind us that there’s so much more to explore, and I look forward to continuing to see where Curiosity will take us.
For more Curiosity blog posts, visit MSL Mission Updates
Learn more about Curiosity’s science instruments
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