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Forest degradation primary driver of carbon loss in the Brazilian Amazon
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By NASA
The 33rd SpaceX commercial resupply services mission for NASA, scheduled to liftoff from the agency’s Kennedy Space Center in Florida in late August, is heading to the International Space Station with an important investigation for the future of bone health.
The experiment will test how microgravity affects bone-forming and bone-degrading cells and explore potential ways to prevent bone loss. This research could help protect astronauts on future long-duration missions to the Moon and Mars, while also advancing treatments for millions of people on Earth who suffer from osteoporosis.
Mesenchymal stem cells (MSCs) are derived from human bone marrow and stained with rapid red dye NASA Space’s Hidden Health Mystery
During long-duration missions, astronauts may experience a gradual reduction in bone density—typically around 1% to 2% per month—even with consistent exercise routines. While scientists understand how bones work on Earth, they aren’t sure exactly why bones weaken so quickly in microgravity.
Previous research aboard the space station revealed that microgravity changes how stem cells behave and what substances they release. Scientists now want to dig deeper into these cellular changes to better understand what causes bone loss in space and explore potential ways to prevent it.
Blocking a Potential Bone Thief
The Microgravity Associated Bone Loss-B (MABL-B) investigation focuses on special stem cells called mesenchymal stem cells, or MSCs. As these cells mature, they build new bone tissue in the body.
Scientists suspect that a protein called IL-6 might be the culprit behind bone problems in space. Data from the earlier MABL-A mission suggests that microgravity promotes the type of IL-6 signaling that enhances bone degradation. The MABL-B experiment will investigate this by testing ways to block this IL-6 signaling pathway.
The experiment will grow mesenchymal stem cells alongside other bone cells in special containers designed for space research. Cells will be cultured for 19 days aboard the space station, with crew members periodically collecting samples for analysis back on Earth.
How this benefits space exploration
The research could lead to targeted treatments that protect astronauts from bone loss during long-duration missions to the Moon, Mars, and beyond. As crews venture farther from Earth, bone health becomes increasingly critical since medical evacuation or emergency return to Earth won’t be possible during Mars missions.
How this benefits humanity
The findings could provide new insights into age-related bone loss that affects millions of people on Earth. Understanding how the IL-6 protein affects bone health may lead to new treatments for osteoporosis and other bone conditions that come with aging.
Related Resources
Microgravity Associated Bone Loss-B (MABL-B) Microgravity Associated Bone Loss-A (MABL-A) Microgravity Expanded Stem Cells About BPS
NASA’s Biological and Physical Sciences Division pioneers scientific discovery and enables exploration by using space environments to conduct investigations not possible on Earth. Studying biological and physical phenomenon under extreme conditions allows researchers to advance the fundamental scientific knowledge required to go farther and stay longer in space, while also benefitting life on Earth.
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By European Space Agency
Data from ESA’s Soil Moisture and Ocean Salinity (SMOS) mission can be used to estimate how much carbon is stored in forests – and a study has improved our understanding of how reliable this proxy is and how long-term datasets from SMOS can help us to monitor this valuable resource.
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By European Space Agency
Europe’s forests play a crucial role in removing carbon dioxide from the atmosphere, but research led by the European Commission’s Joint Research Centre has found their capacity to absorb carbon dioxide has declined in the past decade.
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By European Space Agency
Just a week after its launch, ESA’s Biomass mission has reached another critical milestone on its path to delivering unprecedented insights into the world’s forests and their vital role in Earth’s carbon cycle – the satellite’s 12-metre-diameter antenna is now fully deployed.
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By European Space Agency
As the new Biomass satellite settles into life in orbit following its launch on 29 April, ESA has released its most extensive satellite-based maps of above-ground forest carbon to date. Spanning nearly two decades, the dataset offers the clearest global picture yet of how forest carbon stocks have changed over time.
Developed through ESA’s Climate Change Initiative, this new long-term record integrates data from multiple satellite missions – and will soon be further enhanced by data from the Biomass mission itself.
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