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Axiom Mission 4 Launches to the International Space Station


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      The Vented Fly Box holds and safely transports vials containing flies and fly food. It includes environmental sensors that monitor temperature and relative humidity.NASA/Dominic Hart When it comes to helping NASA scientists better understand the effects of space travel on the human body, fruit flies are the heavyweights of experiments in weightlessness. Because humans and fruit flies share a lot of similar genetic code, they squeeze a lot of scientific value into a conveniently small, light package. 
      Through a new Space Act Agreement between NASA and Axiom Space, the Vented Fly Box will enable fruit flies (Drosophila melanogaster) to launch aboard a SpaceX Dragon spacecraft from NASA’s Kennedy Space Center in Florida. These tiny crew members will join the Axiom Mission 4 crew for scientific investigations on the International Space Station. The goal is to advance research into how spaceflight impacts DNA repair, a key factor in astronaut health on long-term space missions. 
      For decades, NASA has iterated and improved these specialized habitats to safely house generations of fruit flies for their trips to and from space. As the go-to organism for many of its studies, NASA gained unique knowledge and carefully finessed the steps astronauts take to perform the most efficient and rewarding life science experiments in space.
      The study is supported by NASA’s Ames Research Center in California’s Silicon Valley and Axiom Space.
      View the full article
    • By NASA
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      A lot can change in a year for Earth’s forests and vegetation, as springtime and rainy seasons can bring new growth, while cooling temperatures and dry weather can bring a dieback of those green colors. And now, a novel type of NASA visualization illustrates those changes in a full complement of colors as seen from space.
      Researchers have now gathered a complete year of PACE data to tell a story about the health of land vegetation by detecting slight variations in leaf colors. Previous missions allowed scientists to observe broad changes in chlorophyll, the pigment that gives plants their green color and also allows them to perform photosynthesis. But PACE now allows scientists to see three different pigments in vegetation: chlorophyll, anthocyanins, and carotenoids. The combination of these three pigments helps scientists pinpoint even more information about plant health. Credit: NASA’s Goddard Space Flight Center NASA’s Plankton, Aerosol, Cloud, ocean Ecosystem (PACE) satellite is designed to view Earth’s microscopic ocean plants in a new lens, but researchers have proved its hyperspectral use over land, as well.
      Previous missions measured broad changes in chlorophyll, the pigment that gives plants their green color and also allows them to perform photosynthesis. Now, for the first time, PACE measurements have allowed NASA scientists and visualizers to show a complete year of global vegetation data using three pigments: chlorophyll, anthocyanins, and carotenoids. That multicolor imagery tells a clearer story about the health of land vegetation by detecting the smallest of variations in leaf colors.
      “Earth is amazing. It’s humbling, being able to see life pulsing in colors across the whole globe,” said Morgaine McKibben, PACE applications lead at NASA’s Goddard Space Flight Center in Greenbelt, Maryland. “It’s like the overview effect that astronauts describe when they look down at Earth, except we are looking through our technology and data.”
      Anthocyanins, carotenoids, and chlorophyll data light up North America, highlighting vegetation and its health.Credit: NASA’s Scientific Visualization Studio Anthocyanins are the red pigments in leaves, while carotenoids are the yellow pigments – both of which we see when autumn changes the colors of trees. Plants use these pigments to protect themselves from fluctuations in the weather, adapting to the environment through chemical changes in their leaves. For example, leaves can turn more yellow when they have too much sunlight but not enough of the other necessities, like water and nutrients. If they didn’t adjust their color, it would damage the mechanisms they have to perform photosynthesis.
      In the visualization, the data is highlighted in bright colors: magenta represents anthocyanins, green represents chlorophyll, and cyan represents carotenoids. The brighter the colors are, the more leaves there are in that area. The movement of these colors across the land areas show the seasonal changes over time.
      In areas like the evergreen forests of the Pacific Northwest, plants undergo less seasonal change. The data highlights this, showing comparatively steadier colors as the year progresses.
      The combination of these three pigments helps scientists pinpoint even more information about plant health.
      “Shifts in these pigments, as detected by PACE, give novel information that may better describe vegetation growth, or when vegetation changes from flourishing to stressed,” said McKibben. “It’s just one of many ways the mission will drive increased understanding of our home planet and enable innovative, practical solutions that serve society.”
      The Ocean Color Instrument on PACE collects hyperspectral data, which means it observes the planet in 100 different wavelengths of visible and near infrared light. It is the only instrument – in space or elsewhere – that provides hyperspectral coverage around the globe every one to two days. The PACE mission builds on the legacy of earlier missions, such as Landsat, which gathers higher resolution data but observes a fraction of those wavelengths.
      In a paper recently published in Remote Sensing Letters, scientists introduced the mission’s first terrestrial data products.
      “This PACE data provides a new view of Earth that will improve our understanding of ecosystem dynamics and function,” said Fred Huemmrich, research professor at the University of Maryland, Baltimore County, member of the PACE science and applications team, and first author of the paper. “With the PACE data, it’s like we’re looking at a whole new world of color. It allows us to describe pigment characteristics at the leaf level that we weren’t able to do before.”
      As scientists continue to work with these new data, available on the PACE website, they’ll be able to incorporate it into future science applications, which may include forest monitoring or early detection of drought effects.
      By Erica McNamee
      NASA’s Goddard Space Flight Center, Greenbelt, Md.
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      Last Updated Jun 05, 2025 EditorKate D. RamsayerContactKate D. Ramsayerkate.d.ramsayer@nasa.gov Related Terms
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      The SpaceX Dragon spacecraft carrying the Axiom Mission 3 crew is pictured approaching the International Space Station on Jan. 20, 2024.Credit: NASA NASA, Axiom Space, and SpaceX are targeting 8:22 a.m. EDT, Tuesday, June 10, for launch of the fourth private astronaut mission to the International Space Station, Axiom Mission 4.
      The mission will lift off from Launch Complex 39A at NASA’s Kennedy Space Center in Florida. The crew will travel to the orbiting laboratory on a new SpaceX Dragon spacecraft after launching on the company’s Falcon 9 rocket. The targeted docking time is approximately 12:30 p.m., Wednesday, June 11.
      NASA will stream live coverage of launch and arrival activities on NASA+. Learn how to watch NASA content through a variety of platforms, including social media.

      NASA’s mission responsibility is for integrated operations, which begins during the spacecraft’s approach to the space station, continues during the crew’s approximately two-week stay aboard the orbiting laboratory while conducting science, education, and commercial activities, and concludes once the spacecraft exits the station.

      Peggy Whitson, former NASA astronaut and director of human spaceflight at Axiom Space, will command the commercial mission, while ISRO (Indian Space Research Organisation) astronaut Shubhanshu Shukla will serve as pilot. The two mission specialists are ESA (European Space Agency) project astronaut Sławosz Uznański-Wiśniewski of Poland and Tibor Kapu of Hungary.
      As part of a collaboration between NASA and ISRO, Axiom Mission 4 delivers on a commitment highlighted by President Trump and Indian Prime Minister Narendra Modi to send the first ISRO astronaut to the station. The space agencies are participating in five joint science investigations and two in-orbit science, technology, engineering, and mathematics demonstrations. NASA and ISRO have a long-standing relationship built on a shared vision to advance scientific knowledge and expand space collaboration.
      The private mission also carries the first astronauts from Poland and Hungary to stay aboard the space station.
      NASA will join the mission prelaunch teleconference hosted by Axiom Space (no earlier than one hour after completion of the Launch Readiness Review) at 6 p.m., Monday, June 9, with the following participants:
      Dana Weigel, manager, International Space Station Program, NASA Allen Flynt, chief of mission services, Axiom Space William Gerstenmaier, vice president, Build and Flight Reliability, SpaceX Arlena Moses, launch weather officer, 45th Weather Squadron, U.S. Space Force To join the teleconference, media must register with Axiom Space by 12 p.m., Sunday, June 8, at:
      https://bit.ly/4krAQHK
      NASA’s mission coverage is as follows (all times Eastern and subject to change based on real-time operations):


      Tuesday, June 10
      6:15 a.m. – Axiom Space and SpaceX launch coverage begins.
      7:25 a.m. – NASA joins the launch coverage on NASA+.

      8:22 a.m. – Launch

      NASA will end coverage following orbital insertion, which is approximately 15 minutes after launch. As it is a commercial launch, NASA will not provide a clean launch feed on its channels.


      Wednesday, June 11
      10:30 a.m. – Arrival coverage begins on NASA+, Axiom Space, and SpaceX channels.


      12:30 p.m. – Targeted docking to the space-facing port of the station’s Harmony module.
      Arrival coverage will continue through hatch opening and welcome remarks.

      All times are estimates and could be adjusted based on real-time operations after launch. Follow the space station blog for the most up-to-date operations information.
      The International Space Station is a springboard for developing a low Earth economy. NASA’s goal is to achieve a strong economy off the Earth where the agency can purchase services as one of many customers to meet its science and research objectives in microgravity. NASA’s commercial strategy for low Earth orbit provides the government with reliable and safe services at a lower cost, enabling the agency to focus on Artemis missions to the Moon in preparation for Mars while also continuing to use low Earth orbit as a training and proving ground for those deep space missions.
      Learn more about NASA’s commercial space strategy at:
      https://www.nasa.gov/commercial-space
      -end-
      Claire O’Shea
      Headquarters, Washington
      202-358-1100
      claire.a.o’shea@nasa.gov
      Anna Schneider
      Johnson Space Center, Houston
      281-483-5111
      anna.c.schneider@nasa.gov
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      Last Updated Jun 04, 2025 EditorJessica TaveauLocationNASA Headquarters Related Terms
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    • By NASA
      NASA and ISRO (Indian Space Research Organisation) are collaborating to launch scientific investigations aboard Axiom Mission 4, the fourth private astronaut mission to the International Space Station. These studies include examining muscle regeneration, growth of sprouts and edible microalgae, survival of tiny aquatic organisms, and human interaction with electronic displays in microgravity.
      The mission is targeted to launch no earlier than Tuesday, June 10, aboard a SpaceX Dragon spacecraft on the company’s Falcon 9 rocket from NASA’s Kennedy Space Center in Florida
      Regenerating muscle tissue
      Immunofluorescent image of human muscle fibers for Myogenesis-ISRO, showing nuclei (blue) and proteins (red).Institute for Stem Cell Science and Regenerative Medicine, India During long-duration spaceflights, astronauts lose muscle mass, and their muscle cells’ regenerative ability declines. Researchers suspect this may happen because microgravity interferes with metabolism in mitochondria, tiny structures within cells that produce energy. The Myogenesis-ISRO investigation uses muscle stem cell cultures to examine the muscle repair process and test chemicals known to support mitochondrial function. Results could lead to interventions that maintain muscle health during long-duration space missions, help people on Earth with age-related muscle loss and muscle-wasting diseases, and assist athletes and people recovering from surgery.
      Sprouting seeds
      This preflight image shows sprouted fenugreek seeds for the Sprouts-ISRO investigation.Ravikumar Hosamani Lab, University of Agricultural Sciences, India The Sprouts-ISRO investigation looks at the germination and growth in microgravity of seeds from greengram and fenugreek, nutritious plants commonly eaten on the Indian subcontinent. Bioactive compounds in fenugreek seeds also have therapeutic properties, and the leaves contain essential vitamins and minerals. Learning more about how space affects the genetics, nutritional content, and other characteristics over multiple generations of plants could inform the development of ways for future missions to reliably produce plants as a food source. 
      Microalgae growth
      Culture bags for Space Microalgae-ISRO.Redwire Space Microalgae-ISRO studies how microgravity affects microalgae growth and genetics. Highly digestible microalgae species packed with nutrients could be a food source on future space missions. These organisms also grow quickly, produce energy and oxygen, and consume carbon dioxide, traits that could be employed in life support and fuel systems on spacecraft and in certain scenarios on Earth.  
      Tiny but tough
      NASA astronaut Peggy Whitson sets up the BioServe microscope, which will be used by the Voyager Tardigrade-ISRO investigation.NASA Tardigrades are tiny aquatic organisms that can tolerate extreme conditions on Earth. Voyager Tardigrade-ISRO tests the survival of a strain of tardigrades in the harsh conditions of space, including cosmic radiation and ultra-low temperatures, which kill most life forms. Researchers plan to revive dormant tardigrades, count the number of eggs laid and hatched during the mission, and compare the gene expression patterns of populations in space and on the ground. Results could help identify what makes these organisms able to survive extreme conditions and support development of technology to protect astronauts on future missions and those in harsh environments on Earth. 
      Improving electronic interactions
      NASA astronaut Loral O’Hara interacts with a touchscreen. Voyager Displays-ISRO examines how spaceflight affects use of such devices.NASA Research shows that humans interact with touchscreen devices differently in space. Voyager Displays – ISRO examines how spaceflight affects interactions with electronic displays such as pointing tasks, gaze fixation, and rapid eye movements along with how these interactions affect the user’s feelings of stress or wellbeing. Results could support improved design of control devices for spacecraft and habitats on future space missions as well as for aviation and other uses on Earth.
      Download high-resolution photos and videos of the research mentioned in this article.
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