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By NASA
NASA’s SpaceX 33rd commercial resupply mission will launch on the company’s Dragon spacecraft on the SpaceX Falcon 9 rocket to deliver research and supplies to the International Space StationNASA NASA and SpaceX are targeting no earlier than 2:45 a.m. EDT on Sunday, Aug. 24, for the next launch to deliver scientific investigations, supplies, and equipment to the International Space Station.
Filled with more than 5,000 pounds of supplies, the SpaceX Dragon spacecraft, on the company’s Falcon 9 rocket, will lift off from Launch Complex 40 at Cape Canaveral Space Force Station in Florida. Dragon will dock autonomously about 7:30 a.m. on Monday, Aug. 25, to the forward port of the space station’s Harmony module.
NASA’s SpaceX 33rd commercial resupply mission will launch from Launch Complex 40 at Cape Canaveral Space Force Station in Florida.NASA This launch is the 33rd SpaceX commercial resupply services mission to the orbital laboratory for the agency, and the 13th SpaceX launch under the Commercial Resupply Services-2 contract. The first 20 launches were under the original resupply services contract.
Watch agency launch and arrival coverage on NASA+, Netflix, Amazon Prime, and more. Learn how to watch NASA content through a variety of platforms, including social media.
NASA’s live launch coverage will begin at 2:25 a.m. on Aug 24. Dragon’s arrival coverage will begin at 6 a.m. on Aug. 25. For nearly 25 years, the International Space Station has provided research capabilities used by scientists from over 110 countries to conduct more than 4,000 groundbreaking experiments in microgravity. Research conducted aboard the space station advances Artemis missions to the Moon and human exploration of Mars, while providing multiple benefits to humanity.
Arrival & Departure
The SpaceX Dragon spacecraft will arrive at the space station and dock autonomously to the forward port of the station’s Harmony module at approximately 7:30 a.m. on Monday, Aug. 25. NASA astronauts Mike Fincke and Jonny Kim will monitor the spacecraft’s arrival. It will stay docked to the orbiting laboratory for about four months before splashing down and returning critical science and hardware to teams on Earth.
NASA astronauts Mike Fincke and Jonny Kim will monitor the arrival of the SpaceX Dragon cargo spacecraft from the International Space Station.NASA Research Highlights
Preventing bone loss in space
Microgravity Associated Bone Loss-B (MABL-B) assesses the effects of microgravity on bone marrow stem cells and may provide a better understanding of the basic molecular mechanisms of bone loss that occurs during spaceflight and from normal aging on Earth.NASA A study of bone-forming stem cells in microgravity could provide insight into the basic mechanisms of the bone loss astronauts experience during long-duration space flight ahead of future exploration of the Moon and Mars.
Researchers identified a protein in the body called IL-6 that can send signals to stem cells to promote either bone formation or bone loss. This work evaluates whether blocking IL-6 signals could reduce bone loss during spaceflight. Results could improve our understanding of bone loss on Earth due to aging or disease and lead to new prevention and treatment strategies.
Printing parts, tools in space
Printing parts, tools in space
The objective of the Metal 3D printer aboard the International Space Station is to gain experience with operating and evaluating the manufacturing of spare parts in microgravity to support long duration space missions.NASA As mission duration and distance from Earth increase, resupply becomes harder. Additive manufacturing, or 3D printing, could be used to make parts and dedicated tools on demand, enhancing mission autonomy.
Research aboard the space station has made strides in 3D printing with plastic, but it is not suitable for all uses. Investigations from ESA’s (European Space Agency) Metal 3D Printer builds on recent successful printing of the first metal parts in space.
Bioprinting tissue in microgravity
Maturation of Vascularized Liver Tissue Construct in Zero Gravity (MVP Cell-07) is a biotechnology experiment studying bioprinted, or lab grown, liver tissues complete with blood vessels in space. The results could improve astronaut health on long missions and lead to new ways to treat patients on Earth.NASA Researchers plan to bioprint liver tissue containing blood vessels on the ground and examine how the tissue develops in microgravity. Results could help support the eventual production of entire functional organs for transplantation on Earth.
A previous mission tested whether this bioprinted liver tissue survived and functioned in space. This experimental round could show whether microgravity improves the development of the bioprinted tissue.
Biomanufacturing drug-delivery medical devices
The InSPA-Auxilium Bioprinter will test 3D printing medical implant devices designed to deliver drugs and treat various health conditions such as nerve inuries. Printing on the International Space Station may produce higher-quality devices than on Earth.NASA Scientists are creating an implantable device in microgravity that could support nerve regrowth after injuries. The device is created through bioprinting, a type of 3D printing that uses living cells or proteins as raw materials.
Traumatic injuries can create gaps between nerves, and existing treatments have a limited ability to restore nerve function and may result in impaired physical function. A bioprinted device to bridge nerve gaps could accelerate recovery and preserve function.
Cargo Highlights
NASA’s SpaceX 33rd commercial resupply mission will carry over 5,000 pounds of cargo to the International Space Station.NASA Hardware
Launch:
Reboost Kit – This kit will perform a reboost demonstration of the station to maintain its current altitude. The hardware, located in Dragon’s trunk, contains an independent propellant system, separate from the spacecraft’s main system, to fuel two Draco engines using existing hardware and propellant system design. The boost kit will demonstrate the capability to maintain the orbiting lab’s altitude starting in September with a series of burns planned periodically throughout the fall of 2025. During NASA’s SpaceX 31st commercial resupply services mission, the Dragon spacecraft first demonstrated these capabilities on Nov. 8, 2024. Poly Exercise Rope Kit – These exercise ropes distribute the desired exercise loads through a series of pulleys for the Advanced Restrictive Exercise Device. The ropes have a limited life cycle, and it will be necessary to replace them once they have reached their limit. Brine Filter – These filters remove solid particles from liquid in urine during processing as a part of the station’s water recovery system. Acoustic Monitor – A monitor that measures sound and records the data for download. This monitor will replace the sound level meter and the acoustic dosimeter currently aboard the orbiting laboratory. Multi-filtration Bed – This space unit will support the Water Processor Assembly and continue the International Space Station Program’s effort to replace a fleet of degraded units aboard the station to improve water quality through a single bed. Water Separator Orbital Unit – The unit draws air and condensate mixture from a condensing heat exchanger and separates the two components. The air is returned to the cabin air assembly outlet air-flow stream, and the water is delivered to the condensate bus. This unit launches to maintain in-orbit sparing while another is being returned for repair. Anomaly Gas Analyzer Top Assembly – This battery-powered device detects and monitors gases aboard the station, including oxygen, carbon dioxide, hydrogen chloride, hydrogen fluoride, ammonia, carbon monoxide, and hydrogen cyanide. It also measures cabin pressure, humidity, and temperature. It replaces the Compound Specific Analyzer Combustion Products as the primary tool for detecting airborne chemicals and conditions. Separator Pump (Water Recovery and Management) – This electrically-powered pump separates liquids and gases while rotating. It includes a scoop pump that moves the separated liquid into storage containers for use in other systems. The pump also contains sensor components and a filter to reduce electrical interference from the motor. Launching to maintain in-orbit sparing. Reducer Cylinder Assembly & Emergency Portable Breathing Apparatus – Together, this hardware provides 15 minutes of oxygen to a crew member in case of an emergency (smoke, fire, alarm). Two are launching to maintain a minimum in-orbit spare requirement. Passive Separator Flight Experiment – This experiment will test a new method for separating urine and air using existing technology that combines a water-repellent urine hose with an airflow separator from the station’s existing Waste Hygiene Compartment. Improved Resupply Water Tanks – Two tanks, each holding approximately 160 pounds of potable water, to supplement the Urine Processing Assembly. NORS (Nitrogen/Oxygen Recharge System) Maintenance Tank/Recharge Tank Assembly, Nitrogen – The NORS maintenance kit comprises two assemblies: the NORS recharge tank assembly and the NORS vehicle interface assembly. The recharge tank assembly will be pressurized with nitrogen gas for launch. The vehicle interface assembly will protect the recharge tank assembly for launch and stowage aboard the space station. Launching to maintain reserve oxygen levels on station. Swab Kits – These quick-disconnect cleaning kits are designed and created to replace in-orbit inventory. Return:
Oxygen Generation Assembly Pump – The assembly pump converts potable water from the water recovery system into oxygen and hydrogen. The oxygen is sent to the crew cabin, and the hydrogen is either vented or used to produce more water. The International Space Station has been using this process to produce oxygen and hydrogen for 15 years, and this unit will be retired upon its return to Earth. The flight support equipment within will be refurbished and used in a new pump launched aboard a future flight. Carbon Dioxide Monitoring Assembly – A carbon dioxide monitor that measures the gas using the infrared absorption sensor. It expired in July 2025 and will return for refurbishment. Meteoroid Debris Cover Center Section Assembly – This external multilayer insulation provides thermal and micro-meteoroid orbital debris protection on the node port. After it is removed and replaced with a new assembly launching on NASA’s Northrop Grumman 23rd commercial resupply services mission, this unit will return for repair or used for spare parts. Multi-filtration Bed – This spare unit supports the Water Processor Assembly, which improves water quality aboard the International Space Station. Its return is part of an ongoing effort to replace a degraded fleet of in-orbit units. After its use, this multi-filtration bed will be refurbished for future re-flight. Separator Pump – This electrically powered pump separates liquids and gases while rotating. It includes a scoop pump that moves the separated liquid into storage containers for use in other systems. The pump also contains sensor components and a filter to reduce electrical interference from the motor. This unit is designed to run to failure, and after investigation and testing, it will be returned for repair and future flight. Rate Gyro Enclosure Assembly – The Rate Gyro Assembly determines the space station’s rate of angular motion. It is returning for repair and refurbishment and will be used as a spare. NORS (Nitrogen/Oxygen Recharge System) Maintenance Kit (Oxygen) – The NORS Maintenance Kit comprises two assemblies: the NORS Recharge Tank Assembly and the NORS Vehicle Interface Assembly. The recharge tank assembly will be pressurized with Nitrogen gas for launch. The vehicle interface assembly will protect the recharge tank assembly for launch and stowage aboard the space station. They are routinely returned for reuse and re-flight. The kit also includes a VIA bag (vehicle interface assembly) with foam, which is used as a cargo transfer bag for launch and return to protect the tank. Watch, Engage
Watch agency launch and arrival coverage on NASA+, Netflix, Amazon Prime, and more. Learn how to watch NASA content through a variety of platforms, including social media.
NASA’s live launch coverage will begin at 2:25 a.m. on Aug 24. Dragon’s arrival coverage will begin at 6 a.m. on Aug. 25.
Read more about how to watch and engage.
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By NASA
NASA astronauts Mike Fincke (left) and Zena Cardman photographed during training for their trip to the International Space Station at SpaceX facilities in Florida. Credit: SpaceX NASA astronauts Michael Fincke and Zena Cardman will connect with students in Ohio as they answer prerecorded science, technology, engineering, and mathematics (STEM) questions aboard the International Space Station.
The Earth-to-space call will begin at 10:15 a.m. EDT on Wednesday, Aug. 27, and will stream live on the agency’s Learn With NASA YouTube channel.
Media interested in covering the event must RSVP by 5 p.m., Monday, Aug. 25, to Mary Beddell at: 330-492-3500 or at beddellm@plainlocal.org.
The STEM Academy at Glen Oak High School will host this event in Canton, Ohio for high school students. The goal of this event is to expose learners to the excitement and challenges of engineering and technology, while bringing space exploration to life through cross-curricular instruction and language arts.
For nearly 25 years, astronauts have continuously lived and worked aboard the space station, testing technologies, performing science, and developing skills needed to explore farther from Earth. Astronauts communicate with NASA’s Mission Control Center in Houston 24 hours a day through SCaN’s (Space Communications and Navigation) Near Space Network.
Research and technology investigations taking place aboard the space station benefit people on Earth and lay the groundwork for other agency deep space missions. As part of NASA’s Artemis campaign, the agency will send astronauts to the Moon to prepare for future human exploration of Mars, inspiring the world through discovery in a new Golden Age of innovation and exploration.
See more information on NASA in-flight calls at:
https://www.nasa.gov/stemonstation
-end-
Gerelle Dodson
Headquarters, Washington
202-358-1600
gerelle.q.dodson@nasa.gov
Sandra Jones
Johnson Space Center, Houston
281-483-5111
sandra.p.jones@nasa.gov
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Last Updated Aug 21, 2025 LocationNASA Headquarters Related Terms
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By NASA
5 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
This National Aviation Day graphic shows Orville Wright surrounded by the faces of some of NASA’s aeronautical innovators.NASA / Maria Werries The first “A” in NASA stands for Aeronautics – so naturally that means today, Aug. 19, National Aviation Day, is one of our favorite days all year!
National Aviation Day was first proclaimed in 1939 by President Franklin Roosevelt to celebrate the birthday of aviation pioneer Orville Wright, who, with his brother Wilbur, in 1903, were the first humans to achieve powered flight.
Each year since the President first marked the occasion, sky-faring Americans have come together on this date in an annual celebration of flight – a time to revel in spreading our wings and slipping the surly bonds of Earth.
All of us at NASA share in that celebration. We love everything about flight, whether it’s into space or within Earth’s atmosphere.
Our aeronautical innovators are dedicated to improving the design of airplanes to carry on pioneering new technologies in high-speed flight, airframes and propulsion methods, aerospace engineering modelling, and automating airspace and safety management.
Our heritage in aviation research goes back more than 100 years. We’ve helped air travel become a safe, efficient, reliable form of transportation. If you’re heading to an airport, keep an eye out for these NASA-developed aviation technologies you might see on your flight:
WINGLETSNASA studies led to development of vertical extensions that can be attached to wing tips in order to reduce aerodynamic drag without having to increase wingspan. Winglets help increase an airplane’s range, decrease fuel use, and today can be seen on airplanes everywhere.NASA CHEVRON NOZZLESWorking with its industry partners, NASA researchers determined an effective way to reduce noise levels on the ground and in the passenger cabin was to add saw tooth-shaped cut outs, or chevrons, to structures such as exhaust nozzles and cowlings of jet engines.NASA / The Boeing Company GLASS COCKPITS NASA created and tested the concept of replacing dial and gauge instruments with flat panel digital displays. The displays present information more efficiently and provide the flight crew with a more easily understood picture of the aircraft’s health and position.NASA Langley / Sean Smith How Will You Celebrate?
How else can you celebrate National Aviation Day? Here are seven ideas:
Visit your local science museum or NASA visitor center
Explore your local science center for exhibits about aviation and how an airplane flies. And if you live within a short drive from Norfolk, Virginia; Cleveland, or San Francisco, you might consider checking out the visitor centers associated with NASA’s Langley Research Center, Glenn Research Center, or Ames Research Center, respectively. These major NASA field centers play host to the majority of NASA’s aeronautics research. (NASA’s Armstrong Flight Research Center, the fourth of NASA’s aeronautics centers, is located within the restricted area of Edwards Air Force Base in California so they do not have a public visitor’s center.)
Watch an aviation-themed movie
There’s no shortage of classic aviation-themed movies available to watch in any format (streaming, DVD, cinema, library rentals, etc.), and with any snacks (popcorn, nachos, gummies, etc.). We dare not attempt a comprehensive list, but a good place to start is our documentary “X-59: NASA’s “Quesst” for Quiet Supersonic Flight” available to stream on NASA+.
Build an airplane
Why not? It doesn’t have to be big enough to actually fly in – plastic model kits of the world’s most historic aircraft can be just as rewarding and just as educational, especially for kids who might be thinking about a career as an engineer or technician. In fact, many astronauts will tell you their love of aviation and space began with putting models together as a child. Another idea: Grab some LEGO bricks and build the airplane of your dreams. Or make it easy on yourself, fold a paper airplane and shoot it across the room.
Take an introductory flight lesson
Pilots will tell you there is a wonderful sense of freedom in flying, not to mention the incredible views and the personal sense of accomplishment. At the same time, being a pilot is not for everyone, but you won’t know unless you try! Many general aviation airports in the nation have a flight school that may offer an introductory flight lesson at a discounted price. And if you want a taste of flight without leaving the ground, computer desktop flight simulators such as Microsoft Flight Simulator or X-Plane are popular choices and can get you into the virtual sky in short order.
Visit your local library or download a NASA e-book
Aviation-themed books, whether fact or fiction, are all over the shelves of your local library – literally. That’s because there’s no single Dewey Decimal number for aviation. A book about aviation history will be in a different section of the library than a book about how to design an airplane. And creative nonfiction books such as the Mark Vanhoenacker’s “Skyfaring,” or autobiographies such as Eileen Collins’ “Through the Glass Ceiling to the Stars,” are off on yet another shelf. Don’t hesitate to ask your librarian for help. And when you get back from the library, or while still there, jump online and check out the NASA e-books you can download and own for free.
Have a plane spotting picnic near an airport
At Washington’s National Airport, it’s Gravelly Point. In Tampa, Florida it’s International Mall. If you live near a major international airport, chances are you know the best place where the locals can go to watch aircraft take off and land up close. Be sure to take heed of any security restrictions about where you can and can’t go. But once you have your spot picked out, then load up your picnic basket and camp out for an evening of plane spotting. See how many different types of airplanes you can count or identify.
Follow what we’re doing to transform aviation
NASA’s aeronautical innovators are working to transform air transportation to meet the future needs of the global aviation community. Sounds like a big job, right? It is and there are many ways in which NASA is doing this. Improving an airplane’s aerodynamics, making airplanes more efficient and quieter, working with the Federal Aviation Administration to improve air traffic control – the list could go on for many thousands of more words. Bookmark our NASA Aeronautics topic page and follow us on social media @NASAaero.
So remember this National Aviation Day, NASA is with you when you fly!
About the Author
John Gould
Aeronautics Research Mission DirectorateJohn Gould is a member of NASA Aeronautics' Strategic Communications team at NASA Headquarters in Washington, DC. He is dedicated to public service and NASA’s leading role in scientific exploration. Prior to working for NASA Aeronautics, he was a spaceflight historian and writer, having a lifelong passion for space and aviation.
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By NASA
The 33rd SpaceX commercial resupply services mission for NASA, scheduled to liftoff from the agency’s Kennedy Space Center in Florida in late August, is heading to the International Space Station with an important investigation for the future of bone health.
The experiment will test how microgravity affects bone-forming and bone-degrading cells and explore potential ways to prevent bone loss. This research could help protect astronauts on future long-duration missions to the Moon and Mars, while also advancing treatments for millions of people on Earth who suffer from osteoporosis.
Mesenchymal stem cells (MSCs) are derived from human bone marrow and stained with rapid red dye NASA Space’s Hidden Health Mystery
During long-duration missions, astronauts may experience a gradual reduction in bone density—typically around 1% to 2% per month—even with consistent exercise routines. While scientists understand how bones work on Earth, they aren’t sure exactly why bones weaken so quickly in microgravity.
Previous research aboard the space station revealed that microgravity changes how stem cells behave and what substances they release. Scientists now want to dig deeper into these cellular changes to better understand what causes bone loss in space and explore potential ways to prevent it.
Blocking a Potential Bone Thief
The Microgravity Associated Bone Loss-B (MABL-B) investigation focuses on special stem cells called mesenchymal stem cells, or MSCs. As these cells mature, they build new bone tissue in the body.
Scientists suspect that a protein called IL-6 might be the culprit behind bone problems in space. Data from the earlier MABL-A mission suggests that microgravity promotes the type of IL-6 signaling that enhances bone degradation. The MABL-B experiment will investigate this by testing ways to block this IL-6 signaling pathway.
The experiment will grow mesenchymal stem cells alongside other bone cells in special containers designed for space research. Cells will be cultured for 19 days aboard the space station, with crew members periodically collecting samples for analysis back on Earth.
How this benefits space exploration
The research could lead to targeted treatments that protect astronauts from bone loss during long-duration missions to the Moon, Mars, and beyond. As crews venture farther from Earth, bone health becomes increasingly critical since medical evacuation or emergency return to Earth won’t be possible during Mars missions.
How this benefits humanity
The findings could provide new insights into age-related bone loss that affects millions of people on Earth. Understanding how the IL-6 protein affects bone health may lead to new treatments for osteoporosis and other bone conditions that come with aging.
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NASA’s Biological and Physical Sciences Division pioneers scientific discovery and enables exploration by using space environments to conduct investigations not possible on Earth. Studying biological and physical phenomenon under extreme conditions allows researchers to advance the fundamental scientific knowledge required to go farther and stay longer in space, while also benefitting life on Earth.
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By NASA
3 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
GRX-810 is a new metal alloy developed by NASA for 3D printing parts that can withstand the extreme temperatures of rocket engines, allowing affordable printing of high-heat parts.NASA Until now, additive manufacturing, commonly known as 3D printing, of engine components was limited by the lack of affordable metal alloys that could withstand the extreme temperatures of spaceflight. Expensive metal alloys were the only option for 3D printing engine parts until NASA’s Glenn Research Center in Cleveland, Ohio, developed the GRX-810 alloy.
The primary metals in the GRX-810 alloy include nickel, cobalt, and chromium. A ceramic oxide coating on the powdered metal particles increases its heat resistance and improves performance. Known as oxide dispersion strengthened (ODS) alloys, these powders were challenging to manufacture at a reasonable cost when the project started.
However, the advanced dispersion coating technique developed at Glenn employs resonant acoustic mixing. Rapid vibration is applied to a container filled with the metal powder and nano-oxide particles. The vibration evenly coats each metal particle with the oxide, making them inseparable. Even if a manufactured part is ground down to powder and reused, the next component will have the qualities of ODS.
The benefits over common alloys are significant – GRX-10 could last up to a year at 2,000°F under stress loads that would crack any other affordable alloy within hours. Additionally, 3D printing parts using GRX-810 enables more complex shapes compared to metal parts manufactured with traditional methods.
Elementum 3D, an Erie, Colorado-based company, produces GRX-810 for customers in quantities ranging from small batches to over a ton. The company has a co-exclusive license for the NASA-patented alloy and manufacturing process and continues to work with the agency under a Space Act Agreement to improve the material.
“A material under stress or a heavy load at high temperature can start to deform and stretch almost like taffy,” said Jeremy Iten, chief technical officer with Elementum 3D. “Initial tests done on the large-scale production of our GRX-810 alloy showed a lifespan that’s twice as long as the small-batch material initially produced, and those were already fantastic.”
Commercial space and other industries, including aviation, are testing GRX-810 for additional applications. For example, one Elementum 3D customer, Vectoflow, is testing a GRX-810 flow sensor. Flow sensors monitor the speed of gases flowing through a turbine, helping engineers optimize engine performance. However, these sensors can burn out in minutes due to extreme temperatures. Using GRX-810 flow sensors could improve airplane fuel efficiency, reduce emissions and hardware replacements.
Working hand-in-hand with industry, NASA is driving technology developments that are mutually beneficial to the agency and America’s space economy. Learn more: https://spinoff.nasa.gov/
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Last Updated Aug 15, 2025 Related Terms
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