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By NASA
NASA’s Artemis II SLS (Space Launch System) rocket poised to send four astronauts from Earth on a journey around the Moon next year may appear identical to the Artemis I SLS rocket. On closer inspection, though, engineers have upgraded the agency’s Moon rocket inside and out to improve performance, reliability, and safety.
SLS flew a picture perfect first mission on the Artemis I test flight, meeting or exceeding parameters for performance, attitude control, and structural stability to an accuracy of tenths or hundredths of a percent as it sent an uncrewed Orion thousands of miles beyond the Moon. It also returned volumes of invaluable flight data for SLS engineers to analyze to drive improvements.
Teams with NASA’s Exploration Ground Systems integrate the SLS (Space Launch System) Moon rocket with the solid rocket boosters onto mobile launcher 1 inside High Bay 3 of the Vehicle Assembly Building at NASA’s Kennedy Space Center in March 2025. Artemis II is the first crewed test flight under NASA’s Artemis campaign and is another step toward missions on the lunar surface and helping the agency prepare for future human missions to Mars.NASA/Frank Michaux For Artemis II, the major sections of SLS remain unchanged – a central core stage, four RS-25 main engines, two five-segment solid rocket boosters, the ICPS (interim cryogenic propulsion stage), a launch vehicle stage adapter to hold the ICPS, and an Orion stage adapter connecting SLS to the Orion spacecraft. The difference is in the details.
“While we’re proud of our Artemis I performance, which validated our overall design, we’ve looked at how SLS can give our crews a better ride,” said John Honeycutt, NASA’s SLS Program manager. “Some of our changes respond to specific Artemis II mission requirements while others reflect ongoing analysis and testing, as well as lessons learned from Artemis I.”
Engineers have outfitted the ICPS with optical targets that will serve as visual cues to the astronauts aboard Orion as they manually pilot Orion around the upper stage and practice maneuvers to inform docking operations for Artemis III.
The Artemis II rocket includes an improved navigation system compared to Artemis I. Its communications capability also has been improved by repositioning antennas on the rocket to ensure continuous communications with NASA ground stations and the U.S. Space Force’s Space Launch Delta 45 which controls launches along the Eastern Range.
An emergency detection system on the ICPS allows the rocket to sense and respond to problems and notify the crew. The flight safety system adds a time delay to the self-destruct system to allow time for Orion’s escape system to pull the capsule to safety in event of an abort.
The separation motors that push the solid rocket booster away after the elements are no longer needed were angled an additional 15 degrees to increase separation clearance as the rest of the rocket speeds by.
Additionally, SLS will jettison the spent boosters four seconds earlier during Artemis II ascent than occurred during Artemis I. Dropping the boosters several seconds closer to the end of their burn will give engineers flight data to correlate with projections that shedding the boosters several seconds sooner will yield approximately 1,600 pounds of payload to Earth orbit for future SLS flights.
Engineers have incorporated additional improvements based on lessons learned from Artemis I. During the Artemis I test flight the SLS rocket experienced higher-than-expected vibrations near the solid rocket booster attachment points that was caused by unsteady airflow.
To steady the airflow, a pair of six-foot-long strakes flanking each booster’s forward connection points on the SLS intertank will smooth vibrations induced by airflow during ascent, and the rocket’s electronics system was requalified to endure higher levels of vibrations.
Engineers updated the core stage power distribution control unit, mounted in the intertank, which controls power to the rocket’s other electronics and protects against electrical hazards.
These improvements have led to an enhanced rocket to support crew as part of NASA’s Golden Age of innovation and exploration.
The approximately 10-day Artemis II test flight is the first crewed flight under NASA’s Artemis campaign. It is another step toward new U.S.-crewed missions on the Moon’s surface that will help the agency prepare to send the first astronauts – Americans – to Mars.
https://www.nasa.gov/artemis
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Jonathan Deal
Marshall Space Flight Center, Huntsville, Ala.
256.631.9126
jonathan.e.deal@nasa.gov
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Last Updated Sep 17, 2025 EditorLee MohonContactJonathan DealLocationMarshall Space Flight Center Related Terms
Space Launch System (SLS) Artemis Artemis 2 Exploration Ground Systems Marshall Space Flight Center Explore More
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By NASA
5 min read
Avatars for Astronaut Health to Fly on NASA’s Artemis II
An organ chip for conducting bone marrow experiments in space. Emulate NASA announced a trailblazing experiment that aims to take personalized medicine to new heights. The experiment is part of a strategic plan to gather valuable scientific data during the Artemis II mission, enabling NASA to “know before we go” back to the lunar surface and on to Mars.
The AVATAR (A Virtual Astronaut Tissue Analog Response) investigation will use organ-on-a-chip devices, or organ chips, to study the effects of deep space radiation and microgravity on human health. The chips will contain cells from Artemis II astronauts and fly side-by-side with crew on their approximately 10-day journey around the Moon. This research, combined with other studies on the health and performance of Artemis II astronauts, will give NASA insight into how to best protect astronauts as exploration expands to the surface of the Moon, Mars, and beyond.
AVATAR is NASA’s visionary tissue chip experiment that will revolutionize the very way we will do science, medicine, and human multi-planetary exploration.”
Nicky Fox
Associate Administrator, NASA Science Mission Directorate
“AVATAR is NASA’s visionary tissue chip experiment that will revolutionize the very way we will do science, medicine, and human multi-planetary exploration,” said Nicky Fox, associate administrator, Science Mission Directorate at NASA Headquarters in Washington. “Each tissue chip is a tiny sample uniquely created so that we can examine how the effects of deep space act on each human explorer before we go to ensure we pack the appropriate medical supplies tailored to each individual’s needs as we travel back to the Moon, and onward to Mars.”
The investigation is a collaboration between NASA, government agencies, and industry partners, leveraging commercial expertise to gain a deeper understanding of human biology and disease. This research could accelerate innovations in personalized healthcare, both for astronauts in space and patients on Earth.
Organ-on-a-chip: mimic for human health
Organ chips, also referred to as tissue chips or microphysiological systems, are roughly the size of a USB thumb drive and used to help understand — and then predict — how an individual might respond to a variety of stressors, such as radiation or medical treatments, including pharmaceuticals. Essentially, these small devices serve as “avatars” for human organs.
Organ chips contain living human cells that are grown to model the structures and functions of specific regions in human organs, such as the brain, lungs, heart, pancreas, and liver — they can beat like a heart, breathe like a lung, or metabolize like a liver. Tissue chips can be linked together to mimic how organs interact with each other, which is important for understanding how the whole human body responds to stressors or treatments.
Researchers and oncologists use human tissue chips today to understand how a specific patient’s cancer might react to different drugs or radiation treatments. To date, a standard milestone for organs-on-chips has been to keep human cells healthy for 30 days. However, NASA and other research institutions are pushing these boundaries by increasing the longevity of organ chips to a minimum of six months so that scientists can observe diseases and drug therapies over a longer period.
Bone marrow as bellwether
The Artemis II mission will use organ chips created using blood-forming stem and progenitor cells, which originate in the bone marrow, from Artemis II crew members.
Bone marrow is among the organs most sensitive to radiation exposure and, therefore, of central importance to human spaceflight. It also plays a vital role in the immune system, as it is the origin of all adult red and white blood cells, which is why researchers aim to understand how deep space radiation affects this organ.
Studies have shown that microgravity affects the development of bone marrow cells. Although the International Space Station operates in low Earth orbit, which is shielded from most cosmic and solar radiation by the Earth’s magnetosphere, astronauts often experience a loss of bone density. Given that Artemis II crew will be flying beyond this protective layer, AVATAR researchers also seek to understand how the combined stressors of deep space radiation and microgravity affect the developing cells.
To make the bone marrow organ chips, Artemis II astronauts will first donate platelets to a local healthcare system. The cells remaining from their samples will contain a small percentage of bone marrow-derived stem and progenitor cells. NASA-funded scientists at Emulate, Inc., which developed the organ chip technology used in AVATAR, will purify these cells with magnetic beads that bind specifically to them. The purified cells will then be placed in the bone marrow chips next to blood vessel cells and other supporting cells to model the structure and function of the bone marrow.
Investigating how radiation affects the bone marrow can provide insights into how radiation therapy and other DNA-damaging agents, such as chemotherapeutic drugs, impair blood cell formation. Its significance for both spaceflight and medicine on Earth makes the bone marrow an ideal organ to study in the Artemis II AVATAR project.
Passenger for research
“For NASA, organ chips could provide vital data for protecting astronaut health on deep space missions,” said Lisa Carnell, director of NASA’s Biological and Physical Sciences division at NASA Headquarters. “As we go farther and stay longer in space, crew will have only limited access to on-site clinical healthcare. Therefore, it’ll be critical to understand if there are unique and specific healthcare needs of each astronaut, so that we can send the right supplies with them on future missions.”
During the Artemis II mission, the organ chips will be secured in a custom payload developed by Space Tango and mounted inside the capsule during the mission. The battery-powered payload will maintain automated environmental control and media delivery to the organ chips throughout the flight.
For NASA, organ chips could provide vital data for protecting astronaut health on deep space missions.”
Lisa Carnell
Director of NASA’s Biological and Physical Sciences Division
Upon return, researchers at Emulate will examine how spaceflight affected the bone marrow chips by performing single-cell RNA sequencing, a powerful technique that measures how thousands of genes change within individual cells. The scientists will compare data from the flight samples to measurements of crew cells used in a ground-based immunology study happening simultaneously. This will provide the most detailed look at the impact of spaceflight and deep space radiation on developing blood cells to date.
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NASA’s Biological and Physical Sciences Division pioneers scientific discovery and enables exploration by using space environments to conduct investigations not possible on Earth. Studying biological and physical phenomenon under extreme conditions allows researchers to advance the fundamental scientific knowledge required to go farther and stay longer in space, while also benefitting life on Earth.
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By NASA
The Artemis I SLS (Space Launch System) rocket and Orion spacecraft is pictured in the Vehicle Assembly Building at NASA’s Kennedy Space Center in Florida before rollout to launch pad 39B, in March 2022.Credit: NASA/Frank Michaux Media are invited to see NASA’s fully assembled Artemis II SLS (Space Launch System) rocket and Orion spacecraft in mid-October before its crewed test flight around the Moon next year.
The event at NASA’s Kennedy Space Center in Florida will showcase hardware for the Artemis II lunar mission, which will test capabilities needed for deep space exploration. NASA and industry subject matter experts will be available for interviews.
Attendance is open to U.S. citizens and international media. Media accreditation deadlines are as follows:
International media without U.S. citizenship must apply by 11:59 p.m. EDT on Monday, Sept. 22. U.S. media and U.S. citizens representing international media organizations must apply by 11:59 p.m. EDT on Monday, Sept. 29. Media wishing to take part in person must apply for credentials at:
https://media.ksc.nasa.gov
Credentialed media will receive a confirmation email upon approval, along with additional information about the specific date for the mid-October activities when they are determined. NASA’s media accreditation policy is available online. For questions about accreditation, please email: ksc-media-accreditat@mail.nasa.gov. For other questions, please contact the NASA Kennedy newsroom at: 321-867-2468.
Prior to the media event, the Orion spacecraft will transition from the Launch Abort System Facility to the Vehicle Assembly Building at NASA Kennedy, where it will be placed on top of the SLS rocket. The fully stacked rocket will then undergo complete integrated testing and final hardware closeouts ahead of rolling the rocket to Launch Pad 39B for launch. During this effort, technicians will conduct end-to-end communications checkouts, and the crew will practice day of launch procedures during their countdown demonstration test.
Artemis II will send NASA astronauts Reid Wiseman, Victor Glover, Christina Koch, and CSA (Canadian Space Agency) astronaut Jeremy Hansen on an approximately 10-day journey around the Moon and back. As part of a Golden Age of innovation and exploration, Artemis will pave the way for new U.S.-crewed missions on the lunar surface ahead in preparation toward the first crewed mission to Mars.
To learn more about the Artemis II mission, visit:
https://www.nasa.gov/mission/artemis-ii
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Rachel Kraft / Lauren Low
Headquarters, Washington
202-358-1100
rachel.h.kraft@nasa.gov / lauren.e.low@nasa.gov
Tiffany Fairley
Kennedy Space Center, Fla.
321-867-2468
tiffany.l.fairley@nasa.gov
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Last Updated Sep 10, 2025 LocationNASA Headquarters Related Terms
Artemis 2 Artemis Orion Multi-Purpose Crew Vehicle Space Launch System (SLS) View the full article
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By NASA
NASA’s IMAP (Interstellar Mapping and Acceleration Probe) mission will map the boundaries of the heliosphere, the bubble created by the solar wind that protects our solar system from cosmic radiation. Credit: NASA/Princeton/Patrick McPike NASA will hold a media teleconference at 12 p.m. EDT on Thursday, Sept. 4, to discuss the agency’s upcoming Sun and space weather missions, IMAP (Interstellar Mapping and Acceleration Probe) and Carruthers Geocorona Observatory. The two missions are targeting launch on the same rocket no earlier than Tuesday, Sept. 23.
The IMAP mission will map the boundaries of our heliosphere, the vast bubble created by the Sun’s wind that encapsulates our entire solar system. As a modern-day celestial cartographer, IMAP will explore how the heliosphere interacts with interstellar space, as well as chart the range of particles that fill the space between the planets. The IMAP mission also will support near real-time observations of the solar wind and energetic particles. These energetic particles can produce hazardous space weather that can impact spacecraft and other NASA hardware as the agency explores deeper into space, including at the Moon under the Artemis campaign.
NASA’s Carruthers Geocorona Observatory will image the ultraviolet glow of Earth’s exosphere, the outermost region of our planet’s atmosphere. This data will help scientists understand how space weather from the Sun shapes the exosphere and ultimately impacts our planet. The first observation of this glow – called the geocorona – was captured during Apollo 16, when a telescope designed and built by George Carruthers was deployed on the Moon.
Audio of the teleconference will stream live on the agency’s website at:
https://www.nasa.gov/live
Participants include:
Nicky Fox, associate administrator, Science Mission Directorate, NASA Headquarters in Washington Teresa Nieves-Chinchilla, director, Moon to Mars Space Weather Analysis Office, NASA’s Goddard Space Flight Center in Greenbelt, Maryland David J. McComas, IMAP principal investigator, Princeton University Lara Waldrop, Carruthers Geocorona Observatory principal investigator, University of Illinois Urbana-Champaign To participate in the media teleconference, media must RSVP no later than 11 a.m. on Sept. 4 to Sarah Frazier at: sarah.frazier@nasa.gov. NASA’s media accreditation policy is available online.
The IMAP and Carruthers Geocorona Observatory missions will launch on a SpaceX Falcon 9 rocket from Launch Complex 39A at NASA’s Kennedy Space Center in Florida. Also launching on this flight will be the National Oceanic and Atmospheric Administration’s (NOAA) Space Weather Follow On – Lagrange 1 (SWFO-L1), which will monitor solar wind disturbances and detect and track coronal mass ejections before they reach Earth.
David McComas, professor, Princeton University, leads the IMAP mission with an international team of 27 partner institutions. The Johns Hopkins Applied Physics Laboratory in Laurel, Maryland, built the spacecraft and will operate the mission. NASA’s IMAP is the fifth mission in NASA’s Solar Terrestrial Probes Program portfolio.
The Carruthers Geocorona Observatory mission is led by Lara Waldrop from the University of Illinois Urbana-Champaign. Mission implementation is led by the Space Sciences Laboratory at University of California, Berkeley, which also designed and built the two ultraviolet imagers. BAE Systems designed and built the Carruthers spacecraft.
The Solar Terrestrial Probes Program Office, part of the Explorers and Heliophysics Project Division at NASA Goddard, manages the IMAP and Carruthers Geocorona Observatory missions for NASA’s Science Mission Directorate.
NASA’s Launch Services Program, based at NASA Kennedy, manages the launch service for the mission.
To learn more about IMAP, please visit:
https://www.nasa.gov/imap
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Abbey Interrante / Karen Fox
Headquarters, Washington
301-201-0124 / 202-358-1600
abbey.a.interrante@nasa.gov / karen.c.fox@nasa.gov
Sarah Frazier
Goddard Space Flight Center, Greenbelt, Md.
202-853-7191
sarah.frazier@nasa.gov
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Last Updated Aug 28, 2025 EditorJessica TaveauLocationNASA Headquarters Related Terms
Heliophysics Carruthers Geocorona Observatory (GLIDE) Goddard Space Flight Center Heliophysics Division Heliosphere IMAP (Interstellar Mapping and Acceleration Probe) Kennedy Space Center Launch Services Program Science Mission Directorate Solar Terrestrial Probes Program View the full article
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