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By Space Force
The initiative aims to reinvigorate a holistic culture of well-being that empowers Airmen and Guardians to be more dominant, agile and lethal through physical fitness.
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By NASA
NASA and Northrop Grumman are preparing to send the company’s next cargo mission to the International Space Station, flying research to support Artemis missions to the Moon and human exploration of Mars and beyond, while improving life on Earth. SpaceX’s Falcon 9 rocket will launch Northrop Grumman’s 23rd commercial resupply services mission to the orbiting laboratory.
The investigations aboard the Cygnus spacecraft aim to refine semiconductor crystals for next-generation technologies, reduce harmful microbes, improve medication production, and manage fuel pressure.
NASA, Northrop Grumman, and SpaceX are targeting launch in mid-September from Space Launch Complex 40 at Cape Canaveral Space Force Station in Florida.
Read about some of the investigations traveling to the space station:
Better semiconductor crystals
Optical micrograph of a semiconductor composite wafer with embedded semimetal phases extracted from a space grown crystal in the SUBSA facility during Mission 1United Semiconductors LLC Researchers are continuing to fine-tune in-space production of semiconductor crystals, which are critical for modern devices like cellphones and computers.
The space station’s microgravity environment could enable large-scale manufacturing of complex materials, and leveraging the orbiting platform for crystal production is expected to lead to next-generation semiconductor technologies with higher performance, chip yield, and reliability.
“Semiconductor devices fabricated using crystals from a previous mission demonstrated performance gain by a factor of two and device yield enhanced by a factor of 10 compared to Earth-based counterparts,” said Partha S. Dutta, principal investigator, United Semiconductors LLC in Los Alamitos, California.
Dutta highlighted that three independent parties validated microgravity’s benefits for growing semiconductor crystals and that the commercial value of microgravity-enhanced crystals could be worth more than $1 million per kilogram (2.2 pounds).
Space-manufactured crystals could help meet the need for radiation-hardened, low-power, high-speed electronics and sensors for space systems. They also could provide reduced power use, increased speed, and improved safety. The technology also has ground applications, including electric vehicles, waste heat recovery, and medical tools.
Learn more about the SUBSA-InSPA-SSCug experiment.
Lethal light
Germicidal Ultraviolet (UV) light is emitted by an optical fiber running through the center of an agar plateArizona State University Researchers are examining how microgravity affects ultraviolet (UV) light’s ability to prevent the formation of biofilms — communities of microbes that form in water systems. Investigators developed special optical fibers to deliver the UV light, which could provide targeted, long-lasting, and chemical-free disinfection in space and on Earth.
“In any water-based system, bacterial biofilms can form on surfaces like pipes, valves, and sensors,” said co-investigator Paul Westerhoff, a professor at Arizona State University in Tempe. “This can cause serious problems like corrosion and equipment failure, and affect human health.”
The UV light breaks up DNA in microorganisms, preventing them from reproducing and forming biofilms. Preliminary evidence suggests biofilms behave differently in microgravity, which may affect how the UV light reaches and damages bacterial DNA.
“What we’ll learn about biofilms and UV light in microgravity could help us design safer water and air systems not just for space exploration, but for hospitals, homes, and industries back on Earth,” Westerhoff said.
Learn more about the GULBI experiment.
Sowing seeds for pharmaceuticals
NASA astronaut Loral O’Hara displays the specialized sample processor used for pharmaceutical research aboard the International Space StationNASA An investigation using a specialized pharmaceutical laboratory aboard the space station examines how microgravity may alter and enhance crystal structures of drug molecules. Crystal structure can affect the production, storage, effectiveness, and administration of medications.
“We are exploring drugs with applications in cardiovascular, immunologic, and neurodegenerative disease as well as cancer,” said principal investigator Ken Savin of Redwire Space Technologies in Greenville, Indiana. “We expect microgravity to yield larger, more uniform crystals.”
Once the samples return to Earth, researchers at Purdue University in West Lafayette, Indiana, will examine the crystal structures.
The investigators hope to use the space-made crystals as seeds to produce significant numbers of crystals on Earth.
“We have demonstrated this technique with a few examples, but need to see if it works in many examples,” Savin said. “It’s like being on a treasure hunt with every experiment.”
This research also helps enhance and expand commercial use of the space station for next-generation biotechnology research and in-space production of medications.
Learn more about the ADSEP PIL-11 experiment.
Keeping fuel cool
iss0NASA astronaut Joe Acaba installs hardware for the first effort in 2017 aboard the International Space Station to test controlling pressure in cryogenic fuel tanksNASA Many spacecraft use cryogenic or extremely cold fluids as fuel for propulsion systems. These fluids are kept at hundreds of degrees below zero to remain in a liquid state, making them difficult to use in space where ambient temperatures can vary significantly. If these fluids get too warm, they turn into gas and boiloff, or slowly evaporate and escape the tank, affecting fuel efficiency and mission planning.
A current practice to prevent this uses onboard fuel to cool systems before transferring fuel, but this practice is wasteful and not feasible for Artemis missions to the Moon and future exploration of Mars and beyond. A potential alternative is using special gases that do not turn into liquids at cold temperatures to act as a barrier in the tank and control the movement of the fuel.
Researchers are testing this method to control fuel tank pressure in microgravity. It could save an estimated 42% of propellant mass per year, according to Mohammad Kassemi, a researcher at NASA’s National Center for Space Exploration Research and Case Western Reserve University in Cleveland.
The test could provide insights that help improve the design of lightweight, efficient, long-term in-space cryogenic storage systems for future deep space exploration missions.
Learn more about the ZBOT-NC experiment.
Download high-resolution photos and videos of the research highlighted in this feature.
Learn more about the research aboard the International Space Station at:
www.nasa.gov/iss-science
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By NASA
4 min read
Preparations for Next Moonwalk Simulations Underway (and Underwater)
Researchers Kelly Gilkey, Cy Peverill, Daniel Phan, Chase Haddix, and Ariel Tokarz test portable, handheld X-ray systems for use during future long-duration space missions at NASA’s Glenn Research Center in Cleveland on Friday, March 21, 2025. Credit: NASA/Sara Lowthian-Hanna As NASA plans future human exploration missions to the Moon, Mars, and beyond, new and unique challenges emerge — like communication delays and limited return-to-Earth options — so enhanced medical care capabilities are critical. Crews will need non-invasive imaging technology to diagnose medical conditions, like broken bones or dental injuries.
Scientists at NASA’s Glenn Research Center in Cleveland are testing portable, handheld X-ray systems for use during future extended space missions. Having portable X-ray capabilities aboard spacecraft would allow astronauts to immediately assess and treat potential injuries or identify equipment issues without having to disassemble the gear.
“Technological innovations like that of the mini-X-ray will help keep our astronauts healthy as we endeavor farther into space than ever before,” said acting NASA Administrator Sean Duffy. “Future missions to the Moon and Mars will be safer due to the research of our scientists at NASA Glenn.”
NASA reviewed more than 200 commercial systems — analyzing size, weight, image quality, ease-of-use, cost, and safety — and selected three systems for further testing: MinXray, Remedi, and Fujifilm.
“We’re working to provide evidence on why a mini-X-ray system should be included in future space exploration,” said Dr. Chase Haddix, a senior biomedical engineering research contractor working for Universities Space Research Association at NASA Glenn. “These X-rays could be used to detect both clinical and non-clinical diagnostics, meaning they can check an astronaut’s body or identify the location of a tear in an astronaut suit.”
Researchers capture X-ray images of a shape memory alloy rover tire at NASA’s Glenn Research Center in Cleveland on Friday, March 21, 2025. Credit: NASA/Sara Lowthian-Hanna NASA Glenn is collaborating with other centers, including NASA’s Johnson Space Center in Houston and NASA’s Langley Research Center in Hampton, Virginia, and radiography experts at University Hospitals and Cuyahoga Community College in Cleveland.
“We’re fortunate to have enthusiastic medical and radiography experts right here in our community,” said Dr. Cy Peverill, project task lead at NASA Glenn. “Their knowledge and experience are invaluable as we work to test medical technologies that could significantly improve management of astronaut health on future missions to the Moon or Mars.”
Cuyahoga Community College contributed anatomical phantoms, which are lifelike models of the human body, in its radiography laboratory on the Western Campus and dental hygiene clinical facility at the Metropolitan Campus. Faculty and students consulted with NASA researchers on essential imaging principles, including patient positioning, image acquisition, and image quality.
University Hospitals is partnering with NASA Glenn on a medical study with real patients to compare the performance of the X-ray systems against hospital-grade equipment, focusing on usability, image clarity, and diagnostic accuracy.
“Astronauts live and work in small quarters, much smaller spaces than in a hospital,” Haddix said. “The system must be easy to use since astronauts may not be experienced in radiography. The data from these tests will guide the selection of the most suitable system for future missions.”
Researchers capture X-ray images of an astronaut spacesuit at NASA’s Glenn Research Center in Cleveland on Friday, March 21, 2025. Credit: NASA/Sara Lowthian-Hanna Using portable X-rays to improve health care in inaccessible areas is not new, with systems deployed to diagnose medical issues in places such as base camps in Nepal and remote villages in South Africa. NASA researchers theorize that if these systems are successful in high elevations and extreme temperatures on Earth, perhaps they are durable enough for space missions.
Glenn researchers will continue to collect data from all collaborators, including from an X-ray system sourced by SpaceX that launched in April during the Fram2 mission. The crew captured the first human X-ray images in space during their four-day mission to low Earth orbit. NASA plans to select a device near the end of 2025 and will test the chosen system aboard the International Space Station in 2026 or early 2027.
The Mars Campaign Office at NASA Headquarters in Washington and the agency’s Human Research Program at NASA Johnson fund this work as both organizations focus on pursuing technologies and methods to support safe, productive human space travel.
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After a month-long series of exercises across the Indo-Pacific, The Department of the Air Force has concluded its Department-Level Exercises and looks to lessons learned.
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The U.S. Air Force and Space Force held its first National Signing Day ceremony at the historic Rayburn House Office building, Aug. 15.
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