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By NASA
NASA researchers Matt Gregory, right, Arwa Awiess, center, and Andrew Guion, left, discuss live flight data being ingested at the Mission Visualization and Research Control Center (MVRCC) at NASA’s Ames Research Center in California’s Silicon Valley on Aug. 21, 2025.NASA/ Brandon Torres-Navarrete NASA and its partners recently tested a tool for remotely piloted operations that could enable operators to transport people and goods more efficiently within urban areas.
The team’s goal is to ensure that when these remotely piloted aircraft – including electric vertical takeoff and landing vehicles (eVTOLs) – take to the skies, air traffic controllers won’t be overburdened by increased flight operations and safety is maintained across the national airspace.
On Aug. 21, NASA’s Air Traffic Management eXploration Project (ATM-X) assisted Wisk Aero when they flew a Bell 206 helicopter in Hollister, California. The purpose of the flight test was to evaluate and fine-tune a ground-based radar developed by Collins Aerospace. The radar, which provides aircraft location data, could be used during future remotely piloted operations to detect and avoid other aircraft in the vicinity. NASA, Wisk, and Collins researchers also used the flight to test data exchange capabilities across different geographic locations between the groups, a critical capability for future remotely piloted operators in a shared airspace. This work builds on a November 2024 flight test NASA performed with Reliable Robotics and Collins Aerospace.
Initial analysis of the August testing of Collins’ ground-based radar actively and accurately surveilled the airspace during the aircraft’s flight test. The Collins radar system also successfully transmitted these data to NASA’s Mission Visualization Research Command Center lab at NASA’s Ames Research Center in California’s Silicon Valley. NASA, Wisk, and Collins will further analyze the flight data to better understand the radar’s performance and data exchange capabilities for future remotely piloted flight tests. This testing is a part of ATM-X’s remotely piloted testing campaign, designed to identify the infrastructure and technologies needed for the Federal Aviation Administration to safely integrate drones and air taxis into the airspace, bringing the movement of people and goods off the ground, and into the sky.
Remotely piloted eVTOL aircraft could bridge the gap for urban communities by offering a more affordable and accessible method of transportation and delivery services in congested, highly-populated areas.
NASA and Wisk will continue to collaborate on emerging eVTOL technologies to safely integrate advanced aircraft, into the national airspace. Together, the teams will gather data on eVTOL performance and characteristics during a flight test of a helicopter, which will act as a “surrogate” simulating an eVTOL flight. This work will mark another critical step towards better connecting communities across the globe.
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By NASA
The IAU (International Astronomical Union), an international non-governmental research organization and global naming authority for celestial objects, has approved official names for features on Donaldjohanson, an asteroid NASA’s Lucy spacecraft visited on April 20. In a nod to the fossilized inspiration for the names of the asteroid and spacecraft, the IAU’s selections recognize significant sites and discoveries on Earth that further our understanding of humanity’s origins.
The asteroid was named in 2015 after paleoanthropologist Donald Johanson, discoverer of one of the most famous fossils ever found of a female hominin, or ancient human ancestor, nicknamed Lucy. Just as the Lucy fossil revolutionized our understanding of human evolution, NASA’s Lucy mission aims to revolutionize our understanding of solar system evolution by studying at least eight Trojan asteroids that share an orbit with Jupiter.
Postcard commemorating NASA’s Lucy spacecraft April 20, 2025, encounter with the asteroid Donaldjohanson. NASA’s Goddard Space Flight Center Donaldjohanson, located in the main asteroid belt between the orbits of Mars and Jupiter, was a target for Lucy because it offered an opportunity for a comprehensive “dress rehearsal” for Lucy’s main mission, with all three of its science instruments carrying out observation sequences very similar to the ones that will occur at the Trojans.
After exploring the asteroid and getting to see its features up close, the Lucy science and engineering team proposed to name the asteroid’s surface features in recognition of significant paleoanthropological sites and discoveries, which the IAU accepted.
The smaller lobe is called Afar Lobus, after the Ethiopian region where Lucy and other hominin fossils were found. The larger lobe is named Olduvai Lobus, after the Tanzanian river gorge that has also yielded many important hominin discoveries.
The asteroid’s neck, Windover Collum, which joins those two lobes, is named after the Windover Archeological Site near Cape Canaveral Space Force Station in Florida — where NASA’s Lucy mission launched in 2021. Human remains and artifacts recovered from that site revolutionized our understanding of the people who lived in Florida around 7,300 years ago.
Officially recognized names of geologic features on the asteroid Donaldjohanson. NASA Goddard/SwRI/Johns Hopkins APL Two smooth areas on the asteroid’s neck are named Hadar Regio, marking the specific site of Johanson’s discovery of the Lucy fossil, and Minatogawa Regio, after the location where the oldest known hominins in Japan were found. Select boulders and craters on Donaldjohanson are named after notable fossils ranging from pre-Homo sapiens hominins to ancient modern humans. The IAU also approved a coordinate system for mapping features on this uniquely shaped small world.
As of Sept. 9, the Lucy spacecraft was nearly 300 million miles (480 million km) from the Sun en route to its August 2027 encounter with its first Trojan asteroid called Eurybates. This places Lucy about three quarters of the way through the main asteroid belt. Since its encounter with Donaldjohanson, Lucy has been cruising without passing close to any other asteroids, and without requiring any trajectory correction maneuvers.
The team continues to carefully monitor the instruments and spacecraft as it travels farther from the Sun into a cooler environment.
Stay tuned at nasa.gov/lucy for more updates as Lucy continues its journey toward the never-before-explored Jupiter Trojan asteroids.
By Katherine Kretke
Southwest Research Institute
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By NASA
NASA/Michael DeMocker NASA astronauts Matthew Dominick (left) and Mark Vande Hei (right) prepare to fly out to a landing zone in the Rocky Mountains as part of the certification run for the NASA Artemis course on Aug. 26, 2025. The mountains in northern Colorado offer similar visual illusions and flight environments to the Moon.
The newly certified lander flight training course marks a key milestone in crew training for Artemis missions to the Moon. Through Artemis, NASA will explore the lunar South Pole, paving the way for human exploration farther into the solar system, including Mars.
Learn more about the training course.
Image credit: NASA/Michael DeMocker
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By NASA
5 min read
Avatars for Astronaut Health to Fly on NASA’s Artemis II
An organ chip for conducting bone marrow experiments in space. Emulate NASA announced a trailblazing experiment that aims to take personalized medicine to new heights. The experiment is part of a strategic plan to gather valuable scientific data during the Artemis II mission, enabling NASA to “know before we go” back to the lunar surface and on to Mars.
The AVATAR (A Virtual Astronaut Tissue Analog Response) investigation will use organ-on-a-chip devices, or organ chips, to study the effects of deep space radiation and microgravity on human health. The chips will contain cells from Artemis II astronauts and fly side-by-side with crew on their approximately 10-day journey around the Moon. This research, combined with other studies on the health and performance of Artemis II astronauts, will give NASA insight into how to best protect astronauts as exploration expands to the surface of the Moon, Mars, and beyond.
AVATAR is NASA’s visionary tissue chip experiment that will revolutionize the very way we will do science, medicine, and human multi-planetary exploration.”
Nicky Fox
Associate Administrator, NASA Science Mission Directorate
“AVATAR is NASA’s visionary tissue chip experiment that will revolutionize the very way we will do science, medicine, and human multi-planetary exploration,” said Nicky Fox, associate administrator, Science Mission Directorate at NASA Headquarters in Washington. “Each tissue chip is a tiny sample uniquely created so that we can examine how the effects of deep space act on each human explorer before we go to ensure we pack the appropriate medical supplies tailored to each individual’s needs as we travel back to the Moon, and onward to Mars.”
The investigation is a collaboration between NASA, government agencies, and industry partners, leveraging commercial expertise to gain a deeper understanding of human biology and disease. This research could accelerate innovations in personalized healthcare, both for astronauts in space and patients on Earth.
Organ-on-a-chip: mimic for human health
Organ chips, also referred to as tissue chips or microphysiological systems, are roughly the size of a USB thumb drive and used to help understand — and then predict — how an individual might respond to a variety of stressors, such as radiation or medical treatments, including pharmaceuticals. Essentially, these small devices serve as “avatars” for human organs.
Organ chips contain living human cells that are grown to model the structures and functions of specific regions in human organs, such as the brain, lungs, heart, pancreas, and liver — they can beat like a heart, breathe like a lung, or metabolize like a liver. Tissue chips can be linked together to mimic how organs interact with each other, which is important for understanding how the whole human body responds to stressors or treatments.
Researchers and oncologists use human tissue chips today to understand how a specific patient’s cancer might react to different drugs or radiation treatments. To date, a standard milestone for organs-on-chips has been to keep human cells healthy for 30 days. However, NASA and other research institutions are pushing these boundaries by increasing the longevity of organ chips to a minimum of six months so that scientists can observe diseases and drug therapies over a longer period.
Bone marrow as bellwether
The Artemis II mission will use organ chips created using blood-forming stem and progenitor cells, which originate in the bone marrow, from Artemis II crew members.
Bone marrow is among the organs most sensitive to radiation exposure and, therefore, of central importance to human spaceflight. It also plays a vital role in the immune system, as it is the origin of all adult red and white blood cells, which is why researchers aim to understand how deep space radiation affects this organ.
Studies have shown that microgravity affects the development of bone marrow cells. Although the International Space Station operates in low Earth orbit, which is shielded from most cosmic and solar radiation by the Earth’s magnetosphere, astronauts often experience a loss of bone density. Given that Artemis II crew will be flying beyond this protective layer, AVATAR researchers also seek to understand how the combined stressors of deep space radiation and microgravity affect the developing cells.
To make the bone marrow organ chips, Artemis II astronauts will first donate platelets to a local healthcare system. The cells remaining from their samples will contain a small percentage of bone marrow-derived stem and progenitor cells. NASA-funded scientists at Emulate, Inc., which developed the organ chip technology used in AVATAR, will purify these cells with magnetic beads that bind specifically to them. The purified cells will then be placed in the bone marrow chips next to blood vessel cells and other supporting cells to model the structure and function of the bone marrow.
Investigating how radiation affects the bone marrow can provide insights into how radiation therapy and other DNA-damaging agents, such as chemotherapeutic drugs, impair blood cell formation. Its significance for both spaceflight and medicine on Earth makes the bone marrow an ideal organ to study in the Artemis II AVATAR project.
Passenger for research
“For NASA, organ chips could provide vital data for protecting astronaut health on deep space missions,” said Lisa Carnell, director of NASA’s Biological and Physical Sciences division at NASA Headquarters. “As we go farther and stay longer in space, crew will have only limited access to on-site clinical healthcare. Therefore, it’ll be critical to understand if there are unique and specific healthcare needs of each astronaut, so that we can send the right supplies with them on future missions.”
During the Artemis II mission, the organ chips will be secured in a custom payload developed by Space Tango and mounted inside the capsule during the mission. The battery-powered payload will maintain automated environmental control and media delivery to the organ chips throughout the flight.
For NASA, organ chips could provide vital data for protecting astronaut health on deep space missions.”
Lisa Carnell
Director of NASA’s Biological and Physical Sciences Division
Upon return, researchers at Emulate will examine how spaceflight affected the bone marrow chips by performing single-cell RNA sequencing, a powerful technique that measures how thousands of genes change within individual cells. The scientists will compare data from the flight samples to measurements of crew cells used in a ground-based immunology study happening simultaneously. This will provide the most detailed look at the impact of spaceflight and deep space radiation on developing blood cells to date.
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Biological & Physical Sciences Division (BPS)
NASA’s Biological and Physical Sciences Division pioneers scientific discovery and enables exploration by using space environments to conduct investigations not possible on Earth. Studying biological and physical phenomenon under extreme conditions allows researchers to advance the fundamental scientific knowledge required to go farther and stay longer in space, while also benefitting life on Earth.
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By NASA
CSA (Canadian Space Agency) astronaut Jeremy Hansen, alongside NASA astronauts Victor Glover, Reid Wiseman, and Christina Koch, will launch on the Artemis II mission early next year. The crew will participate in human research studies to provide insights about how the body performs in deep space as part of this mission. Credit: (NASA/James Blair) A sweeping collection of astronaut health studies planned for NASA’s Artemis II mission around the Moon will soon provide agency researchers with a glimpse into how deep space travel influences the human body, mind, and behavior.
During an approximately 10-day mission set to launch in 2026, NASA astronauts Reid Wiseman, Victor Glover, and Christina Koch, and CSA (Canadian Space Agency) astronaut Jeremy Hansen will collect and store their saliva, don wrist monitors that track movement and sleep, and offer other essential data for NASA’s Human Research Program and other agency science teams.
“The findings are expected to provide vital insights for future missions to destinations beyond low Earth orbit, including Mars,” said Laurie Abadie, an aerospace engineer for the program at NASA’s Johnson Space Center in Houston, who strategizes about how to carry out studies on Artemis missions. “The lessons we learn from this crew will help us to more safely accomplish deep space missions and research,” she said.
One study on the Artemis II mission, titled Immune Biomarkers, will explore how the immune system reacts to spaceflight. Another study, ARCHeR (Artemis Research for Crew Health and Readiness), will evaluate how crew members perform individually and as a team throughout the mission, including how easily they can move around within the confined space of their Orion spacecraft. Astronauts also will collect a standardized set of measurements spanning multiple physiological systems to provide a comprehensive snapshot of how spaceflight affects the human body as part of a third study called Artemis II Standard Measures. What’s more, radiation sensors placed inside the Orion capsule cells will collect additional information about radiation shielding functionality and organ-on-a-chip devices containing astronaut cells will study how deep space travel affects humans at a cellular level.
“Artemis missions present unique opportunities, and challenges, for scientific research,” said Steven Platts, chief scientist for human research at NASA Johnson.
Platts explained the mission will need to protect against challenges including exposure to higher radiation levels than on the International Space Station, since the crew will be farther from Earth.
“Together, these studies will allow scientists to better understand how the immune system performs in deep space, teach us more about astronauts’ overall well-being ahead of a Mars mission, and help scientists develop ways to ensure the health and success of crew members,” he said.
Another challenge is the relatively small quarters. The habitable volume inside Orion is about the size of a studio apartment, whereas the space station is larger than a six-bedroom house with six sleeping quarters, two bathrooms, a gym, and a 360-degree view bay window. That limitation affects everything from exercise equipment selection to how to store saliva samples.
Previous research has shown that spaceflight missions can weaken the immune system, reactivate dormant viruses in astronauts, and put the health of the crew at risk. Saliva samples from space-based missions have enabled scientists to assess various viruses, hormones, and proteins that reveal how well the immune system works throughout the mission.
But refrigeration to store such samples will not be an option on this mission due to limited space. Instead, for the Immune Biomarkers study, crew members will supply liquid saliva on Earth and dry saliva samples in space and on Earth to assess changes over time. The dry sample process involves blotting saliva onto special paper that’s stored in pocket-sized booklets.
“We store the samples in dry conditions before rehydrating and reconstituting them,” said Brian Crucian, an immunologist with NASA Johnson who’s leading the study. After landing, those samples will be analyzed by agency researchers.
For the ARCHeR study, participating crew members will wear movement and sleep monitors, called actigraphy devices, before, during, and after the mission. The monitors will enable crew members and flight controllers in mission control to study real-time health and behavioral information for crew safety, and help scientists study how crew members’ sleep and activity patterns affect overall health and performance. Other data related to cognition, behavior, and team dynamics will also be gathered before and after the mission.
“Artemis missions will be the farthest NASA astronauts have ventured into space since the Apollo era,” said Suzanne Bell, a NASA psychologist based at Johnson who is leading the investigation. “The study will help clarify key mission challenges, how astronauts work as a team and with mission control, and the usability of the new space vehicle system.”
Another human research study, Artemis II Standard Measures, will involve collecting survey and biological data before, during, and after the Artemis II mission, though blood collection will only occur before and after the mission. Collecting dry saliva samples, conducting psychological assessments, and testing head, eye, and body movements will also be part of the work. In addition, tasks will include exiting a capsule and conducting simulated moonwalk activities in a pressurized spacesuit shortly after return to Earth to investigate how quickly astronauts recover their sense of balance following a mission.
Crew members will provide data for these Artemis II health studies beginning about six months before the mission and extending for about a month after they return to Earth.
NASA also plans to use the Artemis II mission to help scientists characterize the radiation environment in deep space. Several CubeSats, shoe-box sized satellites that will be deployed into high-Earth orbit during Orion’s transit to the Moon, will probe the near-Earth and deep space radiation environment. Data gathered by these CubeSats will help scientists understand how best to shield crew and equipment from harmful space radiation at various distances from Earth.
Crew members will also keep dosimeters in their pockets that measure radiation exposure in real time. Two additional radiation-sensing technologies will also be affixed to the inside of the Orion spacecraft. One type of device will monitor the radiation environment at different shielding locations and alert crew if they need to seek shelter, such as during a solar storm. A separate collection of four radiation monitors, enabled through a partnership with the German Space Agency DLR, will be placed at various points around the cabin by the crew after launch to gather further information.
Other technologies also positioned inside the spacecraft will gather information about the potential biological effects of the deep space radiation environment. These will include devices called organ chips that house human cells derived from the Artemis II astronauts, through a project called AVATAR (A Virtual Astronaut Tissue Analog Response). After the Artemis II lands, scientists will analyze how these organ chips responded to deep space radiation and microgravity on a cellular level.
Together, the insights from all the human research science collected through this mission will help keep future crews safe as humanity extends missions to the Moon and ventures onward to Mars.
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NASA’s Human Research Program
NASA’s Human Research Program pursues methods and technologies to support safe, productive human space travel. Through science conducted in laboratories, ground-based analogs, commercial missions, the International Space Station and Artemis missions, the program scrutinizes how spaceflight affects human bodies and behaviors. Such research drives the program’s quest to innovate ways that keep astronauts healthy and mission ready as human space exploration expands to the Moon, Mars, and beyond.
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