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By NASA
NASA’s Artemis II SLS (Space Launch System) rocket poised to send four astronauts from Earth on a journey around the Moon next year may appear identical to the Artemis I SLS rocket. On closer inspection, though, engineers have upgraded the agency’s Moon rocket inside and out to improve performance, reliability, and safety.
SLS flew a picture perfect first mission on the Artemis I test flight, meeting or exceeding parameters for performance, attitude control, and structural stability to an accuracy of tenths or hundredths of a percent as it sent an uncrewed Orion thousands of miles beyond the Moon. It also returned volumes of invaluable flight data for SLS engineers to analyze to drive improvements.
Teams with NASA’s Exploration Ground Systems integrate the SLS (Space Launch System) Moon rocket with the solid rocket boosters onto mobile launcher 1 inside High Bay 3 of the Vehicle Assembly Building at NASA’s Kennedy Space Center in March 2025. Artemis II is the first crewed test flight under NASA’s Artemis campaign and is another step toward missions on the lunar surface and helping the agency prepare for future human missions to Mars.NASA/Frank Michaux For Artemis II, the major sections of SLS remain unchanged – a central core stage, four RS-25 main engines, two five-segment solid rocket boosters, the ICPS (interim cryogenic propulsion stage), a launch vehicle stage adapter to hold the ICPS, and an Orion stage adapter connecting SLS to the Orion spacecraft. The difference is in the details.
“While we’re proud of our Artemis I performance, which validated our overall design, we’ve looked at how SLS can give our crews a better ride,” said John Honeycutt, NASA’s SLS Program manager. “Some of our changes respond to specific Artemis II mission requirements while others reflect ongoing analysis and testing, as well as lessons learned from Artemis I.”
Engineers have outfitted the ICPS with optical targets that will serve as visual cues to the astronauts aboard Orion as they manually pilot Orion around the upper stage and practice maneuvers to inform docking operations for Artemis III.
The Artemis II rocket includes an improved navigation system compared to Artemis I. Its communications capability also has been improved by repositioning antennas on the rocket to ensure continuous communications with NASA ground stations and the U.S. Space Force’s Space Launch Delta 45 which controls launches along the Eastern Range.
An emergency detection system on the ICPS allows the rocket to sense and respond to problems and notify the crew. The flight safety system adds a time delay to the self-destruct system to allow time for Orion’s escape system to pull the capsule to safety in event of an abort.
The separation motors that push the solid rocket booster away after the elements are no longer needed were angled an additional 15 degrees to increase separation clearance as the rest of the rocket speeds by.
Additionally, SLS will jettison the spent boosters four seconds earlier during Artemis II ascent than occurred during Artemis I. Dropping the boosters several seconds closer to the end of their burn will give engineers flight data to correlate with projections that shedding the boosters several seconds sooner will yield approximately 1,600 pounds of payload to Earth orbit for future SLS flights.
Engineers have incorporated additional improvements based on lessons learned from Artemis I. During the Artemis I test flight the SLS rocket experienced higher-than-expected vibrations near the solid rocket booster attachment points that was caused by unsteady airflow.
To steady the airflow, a pair of six-foot-long strakes flanking each booster’s forward connection points on the SLS intertank will smooth vibrations induced by airflow during ascent, and the rocket’s electronics system was requalified to endure higher levels of vibrations.
Engineers updated the core stage power distribution control unit, mounted in the intertank, which controls power to the rocket’s other electronics and protects against electrical hazards.
These improvements have led to an enhanced rocket to support crew as part of NASA’s Golden Age of innovation and exploration.
The approximately 10-day Artemis II test flight is the first crewed flight under NASA’s Artemis campaign. It is another step toward new U.S.-crewed missions on the Moon’s surface that will help the agency prepare to send the first astronauts – Americans – to Mars.
https://www.nasa.gov/artemis
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Jonathan Deal
Marshall Space Flight Center, Huntsville, Ala.
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By NASA
6 min read
NASA’s IMAP Mission to Study Boundaries of Our Home in Space
Summary
NASA’s new Interstellar Mapping and Acceleration Probe, or IMAP, will launch no earlier than Tuesday, Sept. 23 to study the heliosphere, a giant shield created by the Sun. The mission will chart the heliosphere’s boundaries to help us better understand the protection it offers life on Earth and how it changes with the Sun’s activity. The IMAP mission will also provide near real-time measurements of the solar wind, data that can be used to improve models predicting the impacts of space weather ranging from power-line disruptions to loss of satellites, to the health of voyaging astronauts. Space is a dangerous place — one that NASA continues to explore for the benefit of all. It’s filled with radiation and high-energy particles that can damage DNA and circuit boards alike. Yet life endures in our solar system in part because of the heliosphere, a giant bubble created by the Sun that extends far beyond Neptune’s orbit.
With NASA’s new Interstellar Mapping and Acceleration Probe, or IMAP, launching no earlier than Tuesday, Sept. 23, humanity is set to get a better look at the heliosphere than ever before. The mission will chart the boundaries of the heliosphere to help us better understand the protection it offers and how it changes with the Sun’s activity. The IMAP mission will also provide near real-time measurements of space weather conditions essential for the Artemis campaign and deep space travel.
“With IMAP, we’ll push forward the boundaries of knowledge and understanding of our place not only in the solar system, but our place in the galaxy as a whole,” said Patrick Koehn, IMAP program scientist at NASA Headquarters in Washington. “As humanity expands and explores beyond Earth, missions like IMAP will add new pieces of the space weather puzzle that fills the space between Parker Solar Probe at the Sun and the Voyagers beyond the heliopause.”
Download this video from NASA’s Scientific Visualization Studio.
Domain of Sun
The heliosphere is created by the constant outflow of material and magnetic fields from the Sun called the solar wind. As the solar system moves through the Milky Way, the solar wind’s interaction with interstellar material carves out the bubble of the heliosphere. Studying the heliosphere helps scientists understand our home in space and how it came to be habitable.
As a modern-day celestial cartographer, IMAP will map the boundary of our heliosphere and study how the heliosphere interacts with the local galactic neighborhood beyond. It will chart the vast range of particles, dust, ultraviolet light, and magnetic fields in interplanetary space, to investigate the energization of charged particles from the Sun and their interaction with interstellar space.
The IMAP mission builds on NASA’s Voyager and IBEX (Interstellar Boundary Explorer) missions. In 2012 and 2018, the twin Voyager spacecraft became the first human-made objects to cross the heliosphere’s boundary and send back measurements from interstellar space. It gave scientists a snapshot of what the boundary looked like and where it was in two specific locations. While IBEX has been mapping the heliosphere, it has left many questions unanswered. With 30 times higher resolution and faster imaging, IMAP will help fill in the unknowns about the heliosphere.
Energetic neutral atoms: atomic messengers from our heliosphere’s edge
Of IMAP’s 10 instruments, three will investigate the boundaries of the heliosphere by collecting energetic neutral atoms, or ENAs. Many ENAs originate as positively charged particles released by the Sun but after racing across the solar system, these particles run into particles in interstellar space. In this collision, some of those positively charged particles become neutral, and an energetic neutral atom is born. The interaction also redirects the new ENAs, and some ricochet back toward the Sun.
Charged particles are forced to follow magnetic field lines, but ENAs travel in a straight line, unaffected by the twists, turns, and turbulences in the magnetic fields that permeate space and shape the boundary of the heliosphere. This means scientists can track where these atomic messengers came from and study distant regions of space from afar. The IMAP mission will use the ENAs it collects near Earth to trace back their origins and construct maps of the boundaries of the heliosphere, which would otherwise be invisible from such a distance.
“With its comprehensive state-of-the-art suite of instruments, IMAP will advance our understanding of two fundamental questions of how particles are energized and transported throughout the heliosphere and how the heliosphere itself interacts with our galaxy,” said Shri Kanekal, IMAP mission scientist at NASA’s Goddard Space Flight Center in Greenbelt, Maryland.
The IMAP mission will study the heliosphere, our home in space. NASA/Princeton University/Patrick McPike Space weather: monitoring solar wind
The IMAP mission will also support near real-time observations of the solar wind and energetic solar particles, which can produce hazardous conditions in the space environment near Earth. From its location at Lagrange Point 1, about 1 million miles from Earth toward the Sun, IMAP will provide around a half hour’s warning of dangerous particles headed toward our planet. The mission’s data will help with the development of models that can predict the impacts of space weather ranging from power-line disruptions to loss of satellites.
“The IMAP mission will provide very important information for deep space travel, where astronauts will be directly exposed to the dangers of the solar wind,” said David McComas, IMAP principal investigator at Princeton University.
Cosmic dust: hints of the galaxy beyond
In addition to measuring ENAs and solar wind particles, IMAP will also make direct measurements of interstellar dust — clumps of particles originating outside of the solar system that are smaller than a grain of sand. This space dust is largely composed of rocky or carbon-rich grains leftover from the aftermath of supernova explosions.
The specific elemental composition of this space dust is a postmark for where it comes from in the galaxy. Studying cosmic dust can provide insight into the compositions of stars from far outside our solar system. It will also help scientists significantly advance what we know about these basic cosmic building materials and provide information on what the material between stars is made of.
David McComas leads the mission with an international team of 27 partner institutions. APL is managing the development phase and building the spacecraft, and it will operate the mission. IMAP is the fifth mission in NASA’s Solar Terrestrial Probes Program portfolio. The Explorers and Heliophysics Projects Division at NASA Goddard manages the STP Program for the agency’s Heliophysics Division of NASA’s Science Mission Directorate. NASA’s Launch Services Program, based at NASA’s Kennedy Space Center in Florida, manages the launch service for the mission.
By Mara Johnson-Groh
NASA’s Goddard Space Flight Center, Greenbelt, Md.
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Last Updated Sep 17, 2025 Related Terms
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By NASA
NASA’s Nancy Grace Roman Space Telescope will help scientists better understand our Milky Way galaxy’s less sparkly components — gas and dust strewn between stars, known as the interstellar medium.
One of Roman’s major observing programs, called the Galactic Plane Survey, will peer through our galaxy to its most distant edge, mapping roughly 20 billion stars—about four times more than have currently been mapped. Scientists will use data from these stars to study and map the dust their light travels through, contributing to the most complete picture yet of the Milky Way’s structure, star formation, and the origins of our solar system.
Our Milky Way galaxy is home to more than 100 billion stars that are often separated by trillions of miles. The spaces in between, called the interstellar medium, aren’t empty — they’re sprinkled with gas and dust that are both the seeds of new stars and the leftover crumbs from stars long dead. Studying the interstellar medium with observatories like NASA’s upcoming Nancy Grace Roman Space Telescope will reveal new insight into the galactic dust recycling system.
Credit: NASA/Laine Havens; Music credit: Building Heroes by Enrico Cacace [BMI], Universal Production Music “With Roman, we’ll be able to turn existing artist’s conceptions of the Milky Way into more data-driven models using new constraints on the 3D distribution of interstellar dust,” said Catherine Zucker, an astrophysicist at the Center for Astrophysics | Harvard & Smithsonian in Cambridge, Massachusetts.
Solving Milky Way mystery
Scientists know how our galaxy likely looks by combining observations of the Milky Way and other spiral galaxies. But dust clouds make it hard to work out the details on the opposite side of our galaxy. Imagine trying to map a neighborhood while looking through the windows of a house surrounded by a dense fog.
Roman will see through the “fog” of dust using a specialized camera and filters that observe infrared light — light with longer wavelengths than our eyes can detect. Infrared light is more likely to pass through dust clouds without scattering.
This artist’s concept visualizes different types of light moving through a cloud of particles. Since infrared light has a longer wavelength, it can pass more easily through the dust. That means astronomers observing in infrared light can peer deeper into dusty regions.Credit: NASA’s Goddard Space Flight Center Light with shorter wavelengths, including blue light produced by stars, more easily scatters. That means stars shining through dust appear dimmer and redder than they actually are.
By comparing the observations with information on the source star’s characteristics, astronomers can disentangle the star’s distance from how much its colors have been reddened. Studying those effects reveals clues about the dust’s properties.
“I can ask, ‘how much redder and dimmer is the starlight that Roman detects at different wavelengths?’ Then, I can take that information and relate it back to the properties of the dust grains themselves, and in particular their size,” said Brandon Hensley, a scientist who studies interstellar dust at NASA’s Jet Propulsion Laboratory in Southern California.
Scientists will also learn about the dust’s composition and probe clouds to investigate the physical processes behind changing dust properties.
Clues in dust-influenced starlight hint at the amount of dust between us and a star. Piecing together results from many stars allows astronomers to construct detailed 3D dust maps. That would enable scientists like Zucker to create a model of the Milky Way, which will show us how it looks from the outside. Then scientists can better compare the Milky Way with other galaxies that we only observe from the outside, slotting it into a cosmological perspective of galaxy evolution.
“Roman will add a whole new dimension to our understanding of the galaxy because we’ll see billions and billions more stars,” Zucker said. “Once we observe the stars, we’ll have the dust data as well because its effects are encoded in every star Roman detects.”
Galactic life cycles
The interstellar medium does more than mill about the Milky Way — it fuels star and planet formation. Dense blobs of interstellar medium form molecular clouds, which can gravitationally collapse and kick off the first stages of star development. Young stars eject hot winds that can cause surrounding dust to clump into planetary building blocks.
“Dust carries a lot of information about our origins and how everything came to be,” said Josh Peek, an associate astronomer and head of the data science mission office at the Space Telescope Science Institute in Baltimore, Maryland. “Right now, we’re basically standing on a really large dust grain — Earth was built out of lots and lots of really tiny grains that grew together into a giant ball.”
Roman will identify young clusters of stars in new, distant star-forming regions as well as contribute data on “star factories” previously identified by missions like NASA’s retired Spitzer Space Telescope.
“If you want to understand star formation in different environments, you have to understand the interstellar landscape that seeds it,” Zucker said. “Roman will allow us to link the 3D structure of the interstellar medium with the 3D distribution of young stars across the galaxy’s disk.”
Roman’s new 3D dust maps will refine our understanding of the Milky Way’s spiral structure, the pinwheel-like pattern where stars, gas, and dust bunch up like galactic traffic jams. By combining velocity data with dust maps, scientists will compare observations with predictions from models to help identify the cause of spiral structure—currently unclear.
The role that this spiral pattern plays in star formation remains similarly uncertain. Some theories suggest that galactic congestion triggers star formation, while others contend that these traffic jams gather material but do not stimulate star birth.
Roman will help to solve mysteries like these by providing more data on dusty regions across the entire Milky Way. That will enable scientists to compare many galactic environments and study star birth in specific structures, like the galaxy’s winding spiral arms or its central stellar bar.
NASA’s Nancy Grace Roman Space Telescope will conduct a Galactic Plane Survey to explore our home galaxy, the Milky Way. The survey will map around 20 billion stars, each encoding information about intervening dust and gas called the interstellar medium. Studying the interstellar medium could offer clues about our galaxy’s spiral arms, galactic recycling, and much more.
Credit: NASA, STScI, Caltech/IPAC The astronomy community is currently in the final stages of planning for Roman’s Galactic Plane Survey.
“With Roman’s massive survey of the galactic plane, we’ll be able to have this deep technical understanding of our galaxy,” Peek said.
After processing, Roman’s data will be available to the public online via the Roman Research Nexus and the Barbara A. Mikulski Archive for Space Telescopes, which will each provide open access to the data for years to come.
“People who aren’t born yet are going to be able to do really cool analyses of this data,” Peek said. “We have a really beautiful piece of our heritage to hand down to future generations and to celebrate.”
Roman is slated to launch no later than May 2027, with the team working toward a potential early launch as soon as fall 2026.
The Nancy Grace Roman Space Telescope is managed at NASA’s Goddard Space Flight Center in Greenbelt, Maryland, with participation by NASA’s Jet Propulsion Laboratory and Caltech/IPAC in Southern California, the Space Telescope Science Institute in Baltimore, and a science team comprising scientists from various research institutions. The primary industrial partners are BAE Systems Inc. in Boulder, Colorado; L3Harris Technologies in Rochester, New York; and Teledyne Scientific & Imaging in Thousand Oaks, California.
Download additional images and video from NASA’s Scientific Visualization Studio.
For more information about the Roman Space Telescope, visit:
https://www.nasa.gov/roman
By Laine Havens
NASA’s Goddard Space Flight Center, Greenbelt, Md.
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Last Updated Sep 16, 2025 EditorAshley BalzerContactAshley Balzerashley.m.balzer@nasa.govLocationGoddard Space Flight Center Related Terms
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By NASA
CSA (Canadian Space Agency) astronaut Jeremy Hansen, alongside NASA astronauts Victor Glover, Reid Wiseman, and Christina Koch, will launch on the Artemis II mission early next year. The crew will participate in human research studies to provide insights about how the body performs in deep space as part of this mission. Credit: (NASA/James Blair) A sweeping collection of astronaut health studies planned for NASA’s Artemis II mission around the Moon will soon provide agency researchers with a glimpse into how deep space travel influences the human body, mind, and behavior.
During an approximately 10-day mission set to launch in 2026, NASA astronauts Reid Wiseman, Victor Glover, and Christina Koch, and CSA (Canadian Space Agency) astronaut Jeremy Hansen will collect and store their saliva, don wrist monitors that track movement and sleep, and offer other essential data for NASA’s Human Research Program and other agency science teams.
“The findings are expected to provide vital insights for future missions to destinations beyond low Earth orbit, including Mars,” said Laurie Abadie, an aerospace engineer for the program at NASA’s Johnson Space Center in Houston, who strategizes about how to carry out studies on Artemis missions. “The lessons we learn from this crew will help us to more safely accomplish deep space missions and research,” she said.
One study on the Artemis II mission, titled Immune Biomarkers, will explore how the immune system reacts to spaceflight. Another study, ARCHeR (Artemis Research for Crew Health and Readiness), will evaluate how crew members perform individually and as a team throughout the mission, including how easily they can move around within the confined space of their Orion spacecraft. Astronauts also will collect a standardized set of measurements spanning multiple physiological systems to provide a comprehensive snapshot of how spaceflight affects the human body as part of a third study called Artemis II Standard Measures. What’s more, radiation sensors placed inside the Orion capsule cells will collect additional information about radiation shielding functionality and organ-on-a-chip devices containing astronaut cells will study how deep space travel affects humans at a cellular level.
“Artemis missions present unique opportunities, and challenges, for scientific research,” said Steven Platts, chief scientist for human research at NASA Johnson.
Platts explained the mission will need to protect against challenges including exposure to higher radiation levels than on the International Space Station, since the crew will be farther from Earth.
“Together, these studies will allow scientists to better understand how the immune system performs in deep space, teach us more about astronauts’ overall well-being ahead of a Mars mission, and help scientists develop ways to ensure the health and success of crew members,” he said.
Another challenge is the relatively small quarters. The habitable volume inside Orion is about the size of a studio apartment, whereas the space station is larger than a six-bedroom house with six sleeping quarters, two bathrooms, a gym, and a 360-degree view bay window. That limitation affects everything from exercise equipment selection to how to store saliva samples.
Previous research has shown that spaceflight missions can weaken the immune system, reactivate dormant viruses in astronauts, and put the health of the crew at risk. Saliva samples from space-based missions have enabled scientists to assess various viruses, hormones, and proteins that reveal how well the immune system works throughout the mission.
But refrigeration to store such samples will not be an option on this mission due to limited space. Instead, for the Immune Biomarkers study, crew members will supply liquid saliva on Earth and dry saliva samples in space and on Earth to assess changes over time. The dry sample process involves blotting saliva onto special paper that’s stored in pocket-sized booklets.
“We store the samples in dry conditions before rehydrating and reconstituting them,” said Brian Crucian, an immunologist with NASA Johnson who’s leading the study. After landing, those samples will be analyzed by agency researchers.
For the ARCHeR study, participating crew members will wear movement and sleep monitors, called actigraphy devices, before, during, and after the mission. The monitors will enable crew members and flight controllers in mission control to study real-time health and behavioral information for crew safety, and help scientists study how crew members’ sleep and activity patterns affect overall health and performance. Other data related to cognition, behavior, and team dynamics will also be gathered before and after the mission.
“Artemis missions will be the farthest NASA astronauts have ventured into space since the Apollo era,” said Suzanne Bell, a NASA psychologist based at Johnson who is leading the investigation. “The study will help clarify key mission challenges, how astronauts work as a team and with mission control, and the usability of the new space vehicle system.”
Another human research study, Artemis II Standard Measures, will involve collecting survey and biological data before, during, and after the Artemis II mission, though blood collection will only occur before and after the mission. Collecting dry saliva samples, conducting psychological assessments, and testing head, eye, and body movements will also be part of the work. In addition, tasks will include exiting a capsule and conducting simulated moonwalk activities in a pressurized spacesuit shortly after return to Earth to investigate how quickly astronauts recover their sense of balance following a mission.
Crew members will provide data for these Artemis II health studies beginning about six months before the mission and extending for about a month after they return to Earth.
NASA also plans to use the Artemis II mission to help scientists characterize the radiation environment in deep space. Several CubeSats, shoe-box sized satellites that will be deployed into high-Earth orbit during Orion’s transit to the Moon, will probe the near-Earth and deep space radiation environment. Data gathered by these CubeSats will help scientists understand how best to shield crew and equipment from harmful space radiation at various distances from Earth.
Crew members will also keep dosimeters in their pockets that measure radiation exposure in real time. Two additional radiation-sensing technologies will also be affixed to the inside of the Orion spacecraft. One type of device will monitor the radiation environment at different shielding locations and alert crew if they need to seek shelter, such as during a solar storm. A separate collection of four radiation monitors, enabled through a partnership with the German Space Agency DLR, will be placed at various points around the cabin by the crew after launch to gather further information.
Other technologies also positioned inside the spacecraft will gather information about the potential biological effects of the deep space radiation environment. These will include devices called organ chips that house human cells derived from the Artemis II astronauts, through a project called AVATAR (A Virtual Astronaut Tissue Analog Response). After the Artemis II lands, scientists will analyze how these organ chips responded to deep space radiation and microgravity on a cellular level.
Together, the insights from all the human research science collected through this mission will help keep future crews safe as humanity extends missions to the Moon and ventures onward to Mars.
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NASA’s Human Research Program
NASA’s Human Research Program pursues methods and technologies to support safe, productive human space travel. Through science conducted in laboratories, ground-based analogs, commercial missions, the International Space Station and Artemis missions, the program scrutinizes how spaceflight affects human bodies and behaviors. Such research drives the program’s quest to innovate ways that keep astronauts healthy and mission ready as human space exploration expands to the Moon, Mars, and beyond.
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By NASA
Artemis II NASA astronauts (left to right) Reid Wiseman, Victor Glover, and Christina Koch, and CSA (Canadian Space Agency) astronaut Jeremy Hansen stand in the white room on the crew access arm of the mobile launcher at Launch Pad 39B as part of an integrated ground systems test at Kennedy Space Center in Florida on Wednesday, Sept. 20, 2023. The test ensures the ground systems team is ready to support the crew timeline on launch day.NASA/Frank Michaux With Artemis II, NASA is taking the science of living and working in space beyond low Earth orbit. While the test flight will help confirm the systems and hardware needed for human deep space exploration, the crew also will be serving as both scientists and volunteer research subjects, completing a suite of experiments that will allow NASA to better understand how human health may change in deep space environments. Results will help the agency build future interventions, protocols, and preventative measures to best protect astronauts on future missions to the lunar surface and to Mars.
Science on Artemis II will include seven main research areas:
ARCHeR: Artemis Research for Crew Health and Readiness
NASA’s Artemis II mission provides an opportunity to explore how deep space travel affects sleep, stress, cognition, and teamwork — key factors in astronaut health and performance. While these effects are well-documented in low Earth orbit, they’ve never been fully studied during lunar missions.
Artemis II astronauts will wear wristband devices that continuously monitor movement and sleep patterns throughout the mission. The data will be used for real-time health monitoring and safety assessments, while pre- and post-flight evaluations will provide deeper insights into cognition, behavior, sleep quality, and teamwork in the unique environment of deep space and the Orion spacecraft.
The findings from the test flight will inform future mission planning and crew support systems, helping NASA optimize human performance for the next era of exploration on the Moon and Mars.
Immune Biomarkers
Saliva provides a unique window into how the human immune system functions in a deep space environment. Tracing changes in astronauts’ saliva from before, during, and after the mission will enable researchers to investigate how the human body responds to deep space in unprecedented ways.
Dry saliva will be collected before, during, and after the mission. It will be blotted onto specialized paper in pocket-sized booklets since equipment needed to preserve wet spit samples in space – including refrigeration – will not be available due to volume constraints. To augment that information, liquid saliva and blood samples will be collected before and after the mission.
NASA Astronaut Randy Bresnik prepares to collect a dry saliva sample aboard the International Space Station. The process, which helps scientists investigate how the immune system is affected by spaceflight and will be part of the Artemis II mission, involves blotting saliva onto special paper that’s stored in pocket-sized booklets.Credit: NASA With these wet and dry saliva samples, scientists will gain insights into how the astronauts’ immune systems are affected by the increased stresses of radiation, isolation, and distance from Earth during their deep space flight. They also will examine whether otherwise dormant viruses are reactivated in space, as has been seen previously on the International Space Station with viruses that can cause chickenpox and shingles.
The information gathered from this study, when combined with data from other missions, will help researchers develop ways to keep crew members safe and healthy as we explore farther and travel for longer periods on deep space missions.
AVATAR: A Virtual Astronaut Tissue Analog Response
AVATAR is another important component of NASA’s strategy to gain a holistic understanding of how the deep space environment affects humans. Scientists plan to use organ-on-a-chip technology during Artemis II, marking the first time these devices will be used beyond the Van Allen belts.
Roughly the size of a USB thumb drive, the chips will measure how individual astronauts respond to deep space stressors, including extreme radiation and microgravity. The organ chips will contain cells developed from preflight blood donations provided by crew members to create miniature stand-ins, or “avatars,” of their bone marrow. Bone marrow plays a vital role in the immune system and is particularly sensitive to radiation, which is why scientists selected it for this study.
An organ chip for conducting bone marrow experiments in space. Credit: Emulate
A key goal for this research is to validate whether organ chips can serve as accurate tools for measuring and predicting human responses to stressors. To evaluate this, scientists will compare AVATAR data with space station findings, as well as with samples taken from the crew before and after flight.
AVATAR could inform measures to ensure crew health on future deep space missions, including personalizing medical kits to each astronaut. For citizens on Earth, it could lead to advancements in individualized treatments for diseases such as cancer.
AVATAR is a demonstration of the power of public-private partnerships. It’s a collaboration between government agencies and commercial space companies: NASA, National Center for Advancing Translational Sciences within the National Institutes of Health, Biomedical Advanced Research and Development Authority, Space Tango, and Emulate.
Artemis II Standard Measures
The crew also will become the first astronauts in deep space to participate in the Spaceflight Standard Measures study, an investigation that’s been collecting data from participating crew members aboard the space station and elsewhere since 2018. The study aims to collect a comprehensive snapshot of astronauts’ bodies and minds by gathering a consistent set of core measurements of physiological response.
The crew will provide biological samples including blood, urine, and saliva for evaluating nutritional status, cardiovascular health, and immunological function starting about six months before their launch. The crew also will participate in tests and surveys evaluating balance, vestibular function, muscle performance, changes in their microbiome, as well as ocular and brain health. While in space, data gathering will include an assessment of motion sickness symptoms. After landing, there will be additional tests of head, eye, and body movements, among other functional performance tasks. Data collection will continue for a month after their return.
All this information will be available for scientists interested in studying the effects of spaceflight via request to NASA’s Life Sciences Data Archive. The results from this work could lead to future interventions, technologies, and studies that help predict the adaptability of crews on a Mars mission.
Radiation Sensors Inside Orion
During the uncrewed Artemis I mission, Orion was blanketed in 5,600 passive and 34 active radiation sensors. The information they gathered assured researchers Orion’s design can provide protection for crew members from hazardous radiation levels during lunar missions. That doesn’t mean that scientists don’t want more information, however.
Similar to Artemis I, six active radiation sensors, collectively called the Hybrid Electronic Radiation Assessors, will be deployed at various locations inside the Orion crew module. Crew also will wear dosimeters in their pockets. These sensors will provide warnings of hazardous radiation levels caused by space weather events made by the Sun. If necessary, this data will be used by mission control to drive decisions for the crew to build a shelter to protect from radiation exposure due to space weather.
Additionally, NASA has again partnered the German Space Agency DLR for an updated model of their M-42 sensor – an M-42 EXT – for Artemis II. The new version offers six times more resolution to distinguish between different types of energy, compared to the Artemis I version. This will allow it to accurately measure the radiation exposure from heavy ions which are thought to be particularly hazardous for radiation risk. Artemis II will carry four of the monitors, affixed at points around the cabin by the crew.
Collectively, sensor data will paint a full picture of radiation exposures inside Orion and provide context for interpreting the results of the ARCHeR, AVATAR, Artemis II Standard Measures, and Immune Biomarkers experiments.
Lunar Observations Campaign
The Artemis II crew will take advantage of their location to explore the Moon from above. As the first humans to see the lunar surface up close since 1972, they’ll document their observations through photographs and audio recordings to inform scientists’ understanding of the Moon and share their experience of being far from Earth. It’s possible the crew could be the first humans to see certain areas of the Moon’s far side, though this will depend on the time and date of launch, which will affect which areas of the Moon will be illuminated and therefore visible when the spacecraft flies by.
Spacecraft such as NASA’s Lunar Reconnaissance Orbiter have been surveying and mapping the Moon for decades, but Artemis II provides a unique opportunity for humans to evaluate the lunar surface from above. Human eyes and brains are highly sensitive to subtle changes in color, texture, and other surface characteristics. Having the crew observe the lunar surface directly – equipped with questions that scientists didn’t even know to ask during Apollo missions – could form the basis for future scientific investigations into the Moon’s geological history, the lunar environment, or new impact sites.
This visualization simulates what the crew of Artemis II might see out the Orion windows on the day of their closest approach to the Moon. It compresses 36 hours into a little more than a minute as it flies the virtual camera on a realistic trajectory that swings the spacecraft around the Moon’s far side. This sample trajectory is timed so that the far side is fully illuminated when the astronauts fly by, but other lighting conditions are possible depending on the exact Artemis II launch date. The launch is scheduled for no later than April of 2026. NASA Goddard/Ernie Wright
It will also offer the first opportunity for an Artemis mission to integrate science flight control operations. From their console in the flight control room in mission control, a science officer will consult with a team of scientists with expertise in impact cratering, volcanism, tectonism, and lunar ice, to provide real-time data analysis and guidance to the Artemis II crew in space. During the mission, the lunar science team will be located in mission control’s Science Evaluation Room at NASA’s Johnson Space Center in Houston.
Lessons learned during Artemis II will pave the way for lunar science operations on future missions.
CubeSats
Several additional experiments are hitching a ride to space onboard Artemis II in the form of CubeSats – shoe-box-sized technology demonstrations and scientific experiments. Though separate from the objectives of the Artemis II mission, they may enhance understanding of the space environment.
Technicians install the Korea AeroSpace Administration (KASA) K-Rad Cube within the Orion stage adapter inside the Multi-Payload Processing Facility at NASA’s Kennedy Space Center in Florida on Tuesday, Sept. 2, 2025. The K-Rad Cube, about the size of a shoebox, is one of the CubeSats slated to fly on NASA’s Artemis II test flight in 2026. Credit: NASA Four international space agencies have signed agreements to send CubeSats into space aboard the SLS (Space Launch System) rocket, each with their own objectives. All will be released from an adapter on the SLS upper stage into a high-Earth orbit, where they will conduct an orbital maneuver to reach their desired orbit.
ATENEA – Argentina’s Comisión Nacional de Actividades Espaciales will collect data on radiation doses across various shielding methods, measure the radiation spectrum around Earth, collect GPS data to help optimize future mission design, and validate a long-range communications link.
K-Rad Cube – The Korea Aerospace Administration will use a dosimeter made of material designed to mimic human tissue to measure space radiation and assess biological effects at various altitudes across the Van Allen radiation belt.
Space Weather CubeSat – The Saudi Space Agency will measure aspects of space weather, including radiation, solar X-rays, solar energetic particles, and magnetic fields, at a range of distances from Earth.
TACHELES – The Germany Space Agency DLR will collect measurements on the effects of the space environment on electrical components to inform technologies for lunar vehicles.
Together, these research areas will inform plans for future missions within NASA’s Artemis campaign. Through Artemis, NASA will send astronauts to explore the Moon for scientific discovery, economic benefits, and build the foundation for the first crewed missions to Mars.
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