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NASA Stennis Achieves Major Milestone for In-Flight Software Mission
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By European Space Agency
Video: 00:01:43 An essential part of ESA’s Space Safety programme is dedicated to getting and keeping Earth’s orbits clean from space debris. In the long run, the Agency aspires to stimulate a true circular economy in space, minimising the impact of spaceflight on Earth and its resources where possible. As part of ESA’s Zero Debris approach, new ESA missions will be designed for safe operations and disposal to stop the creation of new debris by 2030.
ESA has now taken another important step on the road towards sustainability in space with its first in-orbit servicing mission RISE, planned for launch in 2029.
RISE is a commercial in-orbit servicing mission that will demonstrate that it can safely rendezvous and dock to a geostationary client satellite, extending the life of geostationary satellites that need support with attitude and orbit control, but are otherwise in working order.
After verifying that it meets all the performance standards in a first demonstration, prime contractor, operator and co-founder D-Orbit will start commercial life extension services for geostationary satellites.
ESA’s RISE mission marks a promising step towards enhancing in-orbit services and technologies, such as refuelling, refurbishment and assembling – all essential elements for creating a circular economy in space.
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By NASA
5 min read
Avatars for Astronaut Health to Fly on NASA’s Artemis II
An organ chip for conducting bone marrow experiments in space. Emulate NASA announced a trailblazing experiment that aims to take personalized medicine to new heights. The experiment is part of a strategic plan to gather valuable scientific data during the Artemis II mission, enabling NASA to “know before we go” back to the lunar surface and on to Mars.
The AVATAR (A Virtual Astronaut Tissue Analog Response) investigation will use organ-on-a-chip devices, or organ chips, to study the effects of deep space radiation and microgravity on human health. The chips will contain cells from Artemis II astronauts and fly side-by-side with crew on their approximately 10-day journey around the Moon. This research, combined with other studies on the health and performance of Artemis II astronauts, will give NASA insight into how to best protect astronauts as exploration expands to the surface of the Moon, Mars, and beyond.
AVATAR is NASA’s visionary tissue chip experiment that will revolutionize the very way we will do science, medicine, and human multi-planetary exploration.”
Nicky Fox
Associate Administrator, NASA Science Mission Directorate
“AVATAR is NASA’s visionary tissue chip experiment that will revolutionize the very way we will do science, medicine, and human multi-planetary exploration,” said Nicky Fox, associate administrator, Science Mission Directorate at NASA Headquarters in Washington. “Each tissue chip is a tiny sample uniquely created so that we can examine how the effects of deep space act on each human explorer before we go to ensure we pack the appropriate medical supplies tailored to each individual’s needs as we travel back to the Moon, and onward to Mars.”
The investigation is a collaboration between NASA, government agencies, and industry partners, leveraging commercial expertise to gain a deeper understanding of human biology and disease. This research could accelerate innovations in personalized healthcare, both for astronauts in space and patients on Earth.
Organ-on-a-chip: mimic for human health
Organ chips, also referred to as tissue chips or microphysiological systems, are roughly the size of a USB thumb drive and used to help understand — and then predict — how an individual might respond to a variety of stressors, such as radiation or medical treatments, including pharmaceuticals. Essentially, these small devices serve as “avatars” for human organs.
Organ chips contain living human cells that are grown to model the structures and functions of specific regions in human organs, such as the brain, lungs, heart, pancreas, and liver — they can beat like a heart, breathe like a lung, or metabolize like a liver. Tissue chips can be linked together to mimic how organs interact with each other, which is important for understanding how the whole human body responds to stressors or treatments.
Researchers and oncologists use human tissue chips today to understand how a specific patient’s cancer might react to different drugs or radiation treatments. To date, a standard milestone for organs-on-chips has been to keep human cells healthy for 30 days. However, NASA and other research institutions are pushing these boundaries by increasing the longevity of organ chips to a minimum of six months so that scientists can observe diseases and drug therapies over a longer period.
Bone marrow as bellwether
The Artemis II mission will use organ chips created using blood-forming stem and progenitor cells, which originate in the bone marrow, from Artemis II crew members.
Bone marrow is among the organs most sensitive to radiation exposure and, therefore, of central importance to human spaceflight. It also plays a vital role in the immune system, as it is the origin of all adult red and white blood cells, which is why researchers aim to understand how deep space radiation affects this organ.
Studies have shown that microgravity affects the development of bone marrow cells. Although the International Space Station operates in low Earth orbit, which is shielded from most cosmic and solar radiation by the Earth’s magnetosphere, astronauts often experience a loss of bone density. Given that Artemis II crew will be flying beyond this protective layer, AVATAR researchers also seek to understand how the combined stressors of deep space radiation and microgravity affect the developing cells.
To make the bone marrow organ chips, Artemis II astronauts will first donate platelets to a local healthcare system. The cells remaining from their samples will contain a small percentage of bone marrow-derived stem and progenitor cells. NASA-funded scientists at Emulate, Inc., which developed the organ chip technology used in AVATAR, will purify these cells with magnetic beads that bind specifically to them. The purified cells will then be placed in the bone marrow chips next to blood vessel cells and other supporting cells to model the structure and function of the bone marrow.
Investigating how radiation affects the bone marrow can provide insights into how radiation therapy and other DNA-damaging agents, such as chemotherapeutic drugs, impair blood cell formation. Its significance for both spaceflight and medicine on Earth makes the bone marrow an ideal organ to study in the Artemis II AVATAR project.
Passenger for research
“For NASA, organ chips could provide vital data for protecting astronaut health on deep space missions,” said Lisa Carnell, director of NASA’s Biological and Physical Sciences division at NASA Headquarters. “As we go farther and stay longer in space, crew will have only limited access to on-site clinical healthcare. Therefore, it’ll be critical to understand if there are unique and specific healthcare needs of each astronaut, so that we can send the right supplies with them on future missions.”
During the Artemis II mission, the organ chips will be secured in a custom payload developed by Space Tango and mounted inside the capsule during the mission. The battery-powered payload will maintain automated environmental control and media delivery to the organ chips throughout the flight.
For NASA, organ chips could provide vital data for protecting astronaut health on deep space missions.”
Lisa Carnell
Director of NASA’s Biological and Physical Sciences Division
Upon return, researchers at Emulate will examine how spaceflight affected the bone marrow chips by performing single-cell RNA sequencing, a powerful technique that measures how thousands of genes change within individual cells. The scientists will compare data from the flight samples to measurements of crew cells used in a ground-based immunology study happening simultaneously. This will provide the most detailed look at the impact of spaceflight and deep space radiation on developing blood cells to date.
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Biological & Physical Sciences Division (BPS)
NASA’s Biological and Physical Sciences Division pioneers scientific discovery and enables exploration by using space environments to conduct investigations not possible on Earth. Studying biological and physical phenomenon under extreme conditions allows researchers to advance the fundamental scientific knowledge required to go farther and stay longer in space, while also benefitting life on Earth.
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By NASA
A SpaceX Falcon 9 rocket carrying Northrop Grumman’s Cygnus XL spacecraft is launched on NASA’s Northrop Grumman Commercial Resupply Services 23 mission to the International Space Station on Sunday, Sept. 14, 2025.Credit: NASA NASA is sending more science, technology demonstrations, and crew supplies to the International Space Station following the successful launch of the agency’s Northrop Grumman Commercial Resupply Services 23 mission, or Northrop Grumman CRS-23.
The company’s Cygnus XL spacecraft, carrying more than 11,000 pounds of cargo to the orbiting laboratory, lifted off at 6:11 p.m. EDT Sunday on a SpaceX Falcon 9 rocket from Space Launch Complex 40 at Cape Canaveral Space Force Station in Florida. This mission is the first flight of the larger, more cargo-capable version of the solar-powered spacecraft.
Cygnus XL is scheduled to be captured at 6:35 a.m. on Wednesday, Sept. 17, by the Canadarm2 robotic arm, which NASA astronaut Jonny Kim will operate with assistance from NASA astronaut Zena Cardman. Following capture, the spacecraft will be installed to the Unity module’s Earth-facing port for cargo unloading.
The resupply mission is carrying dozens of research experiments that will be conducted during Expedition 73, including materials to produce semiconductor crystals in space and equipment to develop improvements for cryogenic fuel tanks. The spacecraft also will deliver a specialized UV light system to prevent the growth of microbe communities that form in water systems and supplies to produce pharmaceutical crystals that could treat cancer and other diseases.
These are just a sample of the hundreds of scientific investigations conducted aboard the station in the areas of biology and biotechnology, Earth and space science, physical sciences, as well as technology development and demonstrations. For nearly 25 years, NASA has supported a continuous U.S. human presence aboard the orbiting laboratory, where astronauts have learned to live and work in space for extended periods of time. The space station is a springboard for developing a low Earth economy and NASA’s next great leaps in exploration, including Artemis missions to the Moon and American astronaut missions to Mars.
NASA’s arrival, capture, and installation coverage are as follows (all times Eastern and subject to change based on real-time operations):
Wednesday, Sept. 17
5 a.m. – Arrival coverage begins on NASA+, Amazon Prime, and more.
6:35 a.m. – Capture of Cygnus XL with the space station’s robotic arm.
8 a.m. – Installation coverage begins on NASA+, Amazon Prime, and more.
All coverage times are estimates and could be adjusted based on operations after launch. Follow the space station blog for the most up-to-date information.
Cygnus XL is scheduled to remain at the orbiting laboratory until March 2026, before it departs and disposes of several thousand pounds of trash through its re-entry into Earth’s atmosphere, where it will harmlessly burn up. The spacecraft is named the S.S. William “Willie” C. McCool, in honor of the NASA astronaut who perished in 2003 during the space shuttle Columbia accident.
Learn more about this NASA commercial resupply mission at:
https://www.nasa.gov/mission/nasas-northrop-grumman-crs-23/
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Josh Finch / Jimi Russell
Headquarters, Washington
202-358-1100
joshua.a.finch@nasa.gov / james.j.russell@nasa.gov
Steven Siceloff
Kennedy Space Center, Fla.
321-876-2468
steven.p.siceloff@nasa.gov
Sandra Jones / Joseph Zakrzewski
Johnson Space Center, Houston
281-483-5111
sandra.p.jones@nasa.gov / joseph.a.zakrzewski@nasa.gov
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Last Updated Sep 14, 2025 LocationNASA Headquarters Related Terms
International Space Station (ISS) Commercial Resupply ISS Research Johnson Space Center Northrop Grumman Commercial Resupply View the full article
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By NASA
Honolulu is pictured here beside a calm sea in 2017. A JPL technology recently detected and confirmed a tsunami up to 45 minutes prior to detection by tide gauges in Hawaii, and it estimated the speed of the wave to be over 580 miles per hour (260 meters per second) near the coast.NASA/JPL-Caltech A massive earthquake and subsequent tsunami off Russia in late July tested an experimental detection system that had deployed a critical component just the day before.
A recent tsunami triggered by a magnitude 8.8 earthquake off Russia’s Kamchatka Peninsula sent pressure waves to the upper layer of the atmosphere, NASA scientists have reported. While the tsunami did not wreak widespread damage, it was an early test for a detection system being developed at the agency’s Jet Propulsion Laboratory in Southern California.
Called GUARDIAN (GNSS Upper Atmospheric Real-time Disaster Information and Alert Network), the experimental technology “functioned to its full extent,” said Camille Martire, one of its developers at JPL. The system flagged distortions in the atmosphere and issued notifications to subscribed subject matter experts in as little as 20 minutes after the quake. It confirmed signs of the approaching tsunami about 30 to 40 minutes before waves made landfall in Hawaii and sites across the Pacific on July 29 (local time).
“Those extra minutes of knowing something is coming could make a real difference when it comes to warning communities in the path,” said JPL scientist Siddharth Krishnamoorthy.
Near-real-time outputs from GUARDIAN must be interpreted by experts trained to identify the signs of tsunamis. But already it’s one of the fastest monitoring tools of its kind: Within about 10 minutes of receiving data, it can produce a snapshot of a tsunami’s rumble reaching the upper atmosphere.
The dots in this graph indicate wave disturbances in the ionosphere as measured be-tween ground stations and navigation satellites. The initial spike shows the acoustic wave coming from the epicenter of the July 29 quake that caused the tsunami; the red squiggle shows the gravity wave the tsunami generated.NASA/JPL-Caltech The goal of GUARDIAN is to augment existing early warning systems. A key question after a major undersea earthquake is whether a tsunami was generated. Today, forecasters use seismic data as a proxy to predict if and where a tsunami could occur, and they rely on sea-based instruments to confirm that a tsunami is passing by. Deep-ocean pressure sensors remain the gold standard when it comes to sizing up waves, but they are expensive and sparse in locations.
“NASA’s GUARDIAN can help fill the gaps,” said Christopher Moore, director of the National Oceanic and Atmospheric Administration Center for Tsunami Research. “It provides one more piece of information, one more valuable data point, that can help us determine, yes, we need to make the call to evacuate.”
Moore noted that GUARDIAN adds a unique perspective: It’s able to sense sea surface motion from high above Earth, globally and in near-real-time.
Bill Fry, chair of the United Nations technical working group responsible for tsunami early warning in the Pacific, said GUARDIAN is part of a technological “paradigm shift.” By directly observing ocean dynamics from space, “GUARDIAN is absolutely something that we in the early warning community are looking for to help underpin next generation forecasting.”
How GUARDIAN works
GUARDIAN takes advantage of tsunami physics. During a tsunami, many square miles of the ocean surface can rise and fall nearly in unison. This displaces a significant amount of air above it, sending low-frequency sound and gravity waves speeding upwards toward space. The waves interact with the charged particles of the upper atmosphere — the ionosphere — where they slightly distort the radio signals coming down to scientific ground stations of GPS and other positioning and timing satellites. These satellites are known collectively as the Global Navigation Satellite System (GNSS).
While GNSS processing methods on Earth correct for such distortions, GUARDIAN uses them as clues.
SWOT Satellite Measures Pacific Tsunami The software scours a trove of data transmitted to more than 350 continuously operating GNSS ground stations around the world. It can potentially identify evidence of a tsunami up to about 745 miles (1,200 kilometers) from a given station. In ideal situations, vulnerable coastal communities near a GNSS station could know when a tsunami was heading their way and authorities would have as much as 1 hour and 20 minutes to evacuate the low-lying areas, thereby saving countless lives and property.
Key to this effort is the network of GNSS stations around the world supported by NASA’s Space Geodesy Project and Global GNSS Network, as well as JPL’s Global Differential GPS network that transmits the data in real time.
The Kamchatka event offered a timely case study for GUARDIAN. A day before the quake off Russia’s northeast coast, the team had deployed two new elements that were years in the making: an artificial intelligence to mine signals of interest and an accompanying prototype messaging system.
Both were put to the test when one of the strongest earthquakes ever recorded spawned a tsunami traveling hundreds of miles per hour across the Pacific Ocean. Having been trained to spot the kinds of atmospheric distortions caused by a tsunami, GUARDIAN flagged the signals for human review and notified subscribed subject matter experts.
Notably, tsunamis are most often caused by large undersea earthquakes, but not always. Volcanic eruptions, underwater landslides, and certain weather conditions in some geographic locations can all produce dangerous waves. An advantage of GUARDIAN is that it doesn’t require information on what caused a tsunami; rather, it can detect that one was generated and then can alert the authorities to help minimize the loss of life and property.
While there’s no silver bullet to stop a tsunami from making landfall, “GUARDIAN has real potential to help by providing open access to this data,” said Adrienne Moseley, co-director of the Joint Australian Tsunami Warning Centre. “Tsunamis don’t respect national boundaries. We need to be able to share data around the whole region to be able to make assessments about the threat for all exposed coastlines.”
To learn more about GUARDIAN, visit:
https://guardian.jpl.nasa.gov
News Media Contacts
Jane J. Lee / Andrew Wang
Jet Propulsion Laboratory, Pasadena, Calif.
626-379-6874 / 818-354-0307
jane.j.lee@jpl.nasa.gov / andrew.wang@jpl.nasa.gov
Written by Sally Younger
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By NASA
Northrop Grumman’s Cygnus cargo craft awaits its capture by the International Space Stations’ Canadarm2 robotic arm, commanded by NASA astronaut Matthew Dominick on Aug. 6, 2024.Credit: NASA NASA’s Northrop Grumman Commercial Resupply Services 23, or Northrop Grumman CRS-23, will deliver more than 11,000 pounds of science and supplies to the International Space Station. This mission will be the first flight of the Cygnus XL, the larger, more cargo-capable version of the company’s solar-powered spacecraft.
The Cygnus XL will launch on a SpaceX Falcon 9 rocket from the Cape Canaveral Space Force Station in Florida. Following arrival, astronauts aboard the space station will use the Canadarm2 to grapple Cygnus XL before robotically installing the spacecraft to the Unity module’s Earth-facing port for cargo unloading. Stream live launch and arrival coverage on NASA+, Amazon Prime, YouTube.
Mission Infographics
NASA’s Northrop Grumman 23 commercial resupply mission will launch on a SpaceX Falcon 9 rocket to deliver research and supplies to the International Space Station.NASA NASA’s Northrop Grumman 23 commercial resupply mission will launch from Space Launch Complex 40 at Cape Canaveral Space Force Station in Florida.NASA NASA selected William “Willie” McCool as an astronaut in 1996. McCool flew as a pilot on STS-107, his first mission. The STS-107 crew, including McCool, died on February 1, 2003, when space shuttle Columbia was lost during reentry over east Texas at about 9 a.m. EST, 16 minutes prior to the scheduled touchdown and NASA’s Kennedy Space Center. NASA’s Northrop Grumman 23 spacecraft is named in his honor.NASA NASA astronauts Jonny Kim and Zena Cardman will be on duty during the Cygnus spacecraft’s approach and rendezvous. Kim will be at the controls of the Canadarm2 robotic arm ready to capture Cygnus as Cardman monitors the vehicle’s arrival.NASA Mission Hardware
IDA Planar Reflector – This is a reflective element used by visiting spacecraft during docking. The spacecraft bounces a laser off the reflector to compute relative range, velocity, and attitude on approach to the International Space Station. Due to degradation found on the installed reflector, this unit will launch to support a future spacewalk to replace the damaged reflector.
Urine Processing Assembly (UPA) Distillation Assembly – The urine processor on the space station uses filtration and distillation to separate water from wastewater to produce potable water. This unit is launching as a spare.
Reactor Health Sensor – Part of the Environmental Control and Life Support System – Water Processing Assembly, includes two sensors with inlet and outlet ports to measure reactor health. This unit is being launched as a spare.
Pressure Management Device – This is an intravehicular activity system for performing pressurization and depressurization of the space station vestibules between the space station hatch and the hatch of a visiting spacecraft or other module, like the NanoRacks Airlock. During depressurization, most of the air will be added to the space station cabin air to save the valuable resource.
Air Selector Valve – This electro-mechanical assembly is used to direct airflow through the Carbon Dioxide Removal Assembly. Two units are launching as spares.
Major Constituent Analyzer Mass Spectrometer Assembly – This assembly monitors the partial pressure levels of nitrogen, oxygen, hydrogen, methane, water vapor, and carbon dioxide aboard station. This unit is launching as a contingency spare.
Major Constituent Analyzer Mass Sample/Series Pump Assembly – This contains plumbing and a pair of solenoid valves to direct sample gas flow to either of the redundant sample pumps. It draws sample gas from the space station’s atmosphere into the analyzer. This unit is launching as a contingency spare.
Major Constituent Analyzer Sample Distribution Assembly – This isolates the gas sample going to the Mass Spectrometer Assembly. The purpose is to distribute gas samples throughout the analyzer. This unit is launching as a contingency spare.
Charcoal Bed – The bed allows the Trace Contaminant Control System to remove high molecular weight contaminants from the station’s atmosphere. This unit is launching as a spare.
Common Cabin Air Assembly Heat Exchanger – This assembly controls cabin air temperature, humidity, and airflow aboard the space station. This unit is launching as a spare.
Sequential Shunt Unit – This regulates the solar array wing voltage when experiencing high levels of direct sunlight; in doing so, it provides usable power to the station’s primary power system. This unit is launching as a spare.
Solid State Lighting Assembly – This is a specialized internal lighting assembly aboard station. NASA will use one lighting assembly to replace a failed unit and will keep the others as spares.
Remote Power Control Module Type V – This module distributes 120V/DC electrical power and provides current-limiting and fault protection to secondary loads aboard the orbiting laboratory. This module is launching as a spare.
Treadmill Isolator Assembly – The Upper, X, Y, and Z Isolator Assemblies are launching as spares for the space station’s treadmill, where they work together to reduce vibration and force transfer when astronauts are running.
Pump Fan Motor Controller – The controller is an electronic controller to modulate the power to the motor windings, which are coils of conductive wire that are wrapped around its core carrying electric current to drive the motor. Windings are commonly used in household appliances, cars (power steering), pumps, and more.
Quick Don Mask Assembly – This mask is used by the crew, along with the Pre-Breath Assembly, in emergency situations. This unit is launching to replace a unit aboard station.
Anomaly Gas Analyzer – This analyzer senses various gases, like oxygen, carbon dioxide, carbon monoxide, ammonia, and others, along with cabin pressure, water vapor and temperature. Two units are launching as an upgrade to the current analyzer system used on board.
Nitrogen, Oxygen Resupply Maintenance Kit – One tank of nitrogen and one tank of oxygen used for gas replenishment aboard the space station are launching to maintain gas reserves.
Crew and Equipment Translation Aid Luminaire – This is a lighting unit used aboard station to illuminate the astronauts’ equipment cart and surrounding work areas during spacewalks.
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